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The diagnosis of diabetic retinopathy, which relies on fundus images, faces challenges in achieving transparency and interpretability when using a global classification approach. However, segmentation-based databases are significantly more…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Clément Playout , Renaud Duval , Marie Carole Boucher , Farida Cheriet

Machine learning is gaining significant attention as a diagnostic tool in medical imaging, particularly in the analysis of retinal fundus images. However, this approach is not yet clinically applicable, as it still depends on human…

Human-Computer Interaction · Computer Science 2025-10-03 Mattea Reid , Zuhairah Zainal , Khaing Zin Than , Danielle Chan , Jonathan Chan

A retinal trait, or phenotype, summarises a specific aspect of a retinal image in a single number. This can then be used for further analyses, e.g. with statistical methods. However, reducing an aspect of a complex image to a single,…

Quantitative Methods · Quantitative Biology 2022-07-14 Justin Engelmann , Ana Villaplana-Velasco , Amos Storkey , Miguel O. Bernabeu

Medical image segmentation is an important task for computer aided diagnosis. Pixelwise manual annotations of large datasets require high expertise and is time consuming. Conventional data augmentations have limited benefit by not fully…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Dwarikanath Mahapatra , Behzad Bozorgtabar , Jean-Philippe Thiran , Ling Shao

Retinopathy of Prematurity (ROP) is an eye disorder primarily affecting premature infants with lower weights. It causes proliferation of vessels in the retina and could result in vision loss and, eventually, retinal detachment, leading to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Alexander Ding , Qilei Chen , Yu Cao , Benyuan Liu

Due to the fractal nature of retinal blood vessels, the retinal fractal dimension is a natural parameter for researchers to explore and has garnered interest as a potential diagnostic tool. This review aims to summarize the current…

Quantitative Methods · Quantitative Biology 2021-01-25 Sam Yu , Vasudevan Lakshminarayanan

Despite the revolutionary impact of AI and the development of locally trained algorithms, achieving widespread generalized learning from multi-modal data in medical AI remains a significant challenge. This gap hinders the practical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Fatema-E Jannat , Sina Gholami , Minhaj Nur Alam , Hamed Tabkhi

Fundus photography is the primary method for retinal imaging and essential for diabetic retinopathy prevention. Automated segmentation of fundus photographs would improve the quality, capacity, and cost-effectiveness of eye care screening…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Jan Kukačka , Anja Zenz , Marcel Kollovieh , Dominik Jüstel , Vasilis Ntziachristos

Purpose: To assess whether the three-dimensional (3D) structural configuration of the central retinal vessel trunk and its branches (CRVT&B) could be used as a diagnostic marker for glaucoma. Method: We trained a deep learning network to…

Objective Automatic artery/vein (A/V) segmentation from fundus images is required to track blood vessel changes occurring with many pathologies including retinopathy and cardiovascular pathologies. One of the clinical measures that…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Fantin Girard , Conrad Kavalec , Farida Cheriet

Retinal blood vessels are considered to be the reliable diagnostic biomarkers of ophthalmologic and diabetic retinopathy. Monitoring and diagnosis totally depends on expert analysis of both thin and thick retinal vessels which has recently…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Waseem Abbas , Muhammad Haroon Shakeel , Numan Khurshid , Murtaza Taj

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Jia-Hong Huang

According to the World Health Organization, 285 million people worldwide live with visual impairment. The most commonly used imaging technique for diagnosis in ophthalmology is optical coherence tomography (OCT). However, analysis of…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Max-Heinrich Laves , Sontje Ihler , Lüder A. Kahrs , Tobias Ortmaier

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

In this work, we propose an AI-based method that intends to improve the conventional retinal disease treatment procedure and help ophthalmologists increase diagnosis efficiency and accuracy. The proposed method is composed of a deep neural…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Jia-Hong Huang , Chao-Han Huck Yang , Fangyu Liu , Meng Tian , Yi-Chieh Liu , Ting-Wei Wu , I-Hung Lin , Kang Wang , Hiromasa Morikawa , Hernghua Chang , Jesper Tegner , Marcel Worring

Automated surface segmentation of retinal layer is important and challenging in analyzing optical coherence tomography (OCT). Recently, many deep learning based methods have been developed for this task and yield remarkable performance.…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Hong Liu , Dong Wei , Donghuan Lu , Yuexiang Li , Kai Ma , Liansheng Wang , Yefeng Zheng

Segmentation of macro and microvascular structures in fundoscopic retinal images plays a crucial role in the detection of multiple retinal and systemic diseases, yet it is a difficult problem to solve. Most neural network approaches face…

Image and Video Processing · Electrical Eng. & Systems 2022-06-30 Shikhar Mohan , Saumik Bhattacharya , Sayantari Ghosh

Retinal vessel segmentation is crucial for intelligent ophthalmic diagnosis, yet it faces three major challenges: insufficient multi-scale feature fusion, disruption of contextual continuity, and noise interference. This study proposes a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Xinran Xu , Yuliang Ma , Sifu Cai , Ming Meng , Qiang Lv , Ruoyan Shi

The automatic diagnosis of various retinal diseases from fundus images is important to support clinical decision-making. However, developing such automatic solutions is challenging due to the requirement of a large amount of human-annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xiaomeng Li , Mengyu Jia , Md Tauhidul Islam , Lequan Yu , Lei Xing