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Retinal imaging is fast, non-invasive, and widely available, offering quantifiable structural and vascular signals for ophthalmic and systemic health assessment. This accessibility creates an opportunity to study how quantitative retinal…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Zhonghua Wang , Lie Ju , Sijia Li , Wei Feng , Sijin Zhou , Ming Hu , Jianhao Xiong , Xiaoying Tang , Yifan Peng , Mingquan Lin , Yaodong Ding , Yong Zeng , Wenbin Wei , Li Dong , Zongyuan Ge

Automatic segmentation of retinal blood vessels from fundus images plays an important role in the computer aided diagnosis of retinal diseases. The task of blood vessel segmentation is challenging due to the extreme variations in morphology…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Avijit Dasgupta , Sonam Singh

Retinal imaging has emerged as a promising method of addressing this challenge, taking advantage of the unique structure of the retina. The retina is an embryonic extension of the central nervous system, providing a direct in vivo window…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Syed Javed , Tariq M. Khan , Abdul Qayyum , Arcot Sowmya , Imran Razzak

Accurate retinal vessel segmentation is an important task for many computer-aided diagnosis systems. Yet, it is still a challenging problem due to the complex vessel structures of an eye. Numerous vessel segmentation methods have been…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Ali Karaali , Rozenn Dahyot , Donal J. Sexton

The study of the retinal vasculature is a fundamental stage in the screening and diagnosis of many diseases. A complete retinal vascular analysis requires to segment and classify the blood vessels of the retina into arteries and veins…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 José Morano , Álvaro S. Hervella , Jorge Novo , José Rouco

Retinal vessel segmentation plays a vital role in analyzing fundus images for the diagnosis of systemic and ocular diseases. Building on this, classifying segmented vessels into arteries and veins (A/V) further enables the extraction of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Shuang Zeng , Chee Hong Lee , Kaiwen Li , Boxu Xie , Ourui Fu , Hangzhou He , Lei Zhu , Yanye Lu , Fangxiao Cheng

This paper presents a method for retinal vasculature extraction based on biologically inspired multi-orientation analysis. We apply multi-orientation analysis via so-called invertible orientation scores, modeling the cortical columns in the…

Computer Vision and Pattern Recognition · Computer Science 2015-04-09 Erik Bekkers , Remco Duits , Tos Berendschot , Bart ter Haar Romeny

People with diabetes are at risk of developing an eye disease called diabetic retinopathy (DR). This disease occurs when high blood glucose levels cause damage to blood vessels in the retina. Computer-aided DR diagnosis is a promising tool…

Computer Vision and Pattern Recognition · Computer Science 2020-11-12 Yi Zhou , Boyang Wang , Lei Huang , Shanshan Cui , Ling Shao

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Retinal vessel segmentation plays an imaportant role in the field of retinal image analysis because changes in retinal vascular structure can aid in the diagnosis of diseases such as hypertension and diabetes. In recent research, numerous…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Changlu Guo , Márton Szemenyei , Yugen Yi , Ying Xue , Wei Zhou , Yangyuan Li

Vascular structures in the retina contain important information for the detection and analysis of ocular diseases, including age-related macular degeneration, diabetic retinopathy and glaucoma. Commonly used modalities in diagnosis of these…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Erick O. Rodrigues , Aura Conci , Panos Liatsis

Accurate retinal vessel (RV) segmentation is a crucial step in the quantitative assessment of retinal vasculature, which is needed for the early detection of retinal diseases and other conditions. Numerous studies have been conducted to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Trung Dang , Huy Hoang Nguyen , Aleksei Tiulpin

Retinal vessel segmentation is an indispensable step for automatic detection of retinal diseases with fundoscopic images. Though many approaches have been proposed, existing methods tend to miss fine vessels or allow false positives at…

Computer Vision and Pattern Recognition · Computer Science 2017-07-03 Jaemin Son , Sang Jun Park , Kyu-Hwan Jung

Retinal vessel segmentation is critical for diagnosing ocular conditions, yet current deep learning methods are limited by modality-specific challenges and significant distribution shifts across imaging devices, resolutions, and anatomical…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Zixuan Liu , Aaron Honjaya , Yuekai Xu , Yi Zhang , Hefu Pan , Xin Wang , Linda G Shapiro , Sheng Wang , Ruikang K Wang

Segmenting the retinal vasculature entails a trade-off between how much of the overall vascular structure we identify vs. how precisely we segment individual vessels. In particular, state-of-the-art methods tend to under-segment faint…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Aashis Khanal , Rolando Estrada

The appearance and structure of blood vessels in retinal images have an important role in diagnosis of diseases. This paper proposes a method for automatic retinal vessel segmentation. In this work, a novel preprocessing based on local…

Computer Vision and Pattern Recognition · Computer Science 2013-12-31 Saeid Fazli , Sevin Samadi

The reliable segmentation of retinal vasculature can provide the means to diagnose and monitor the progression of a variety of diseases affecting the blood vessel network, including diabetes and hypertension. We leverage the power of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-23 Ali Hatamizadeh , Hamid Hosseini , Zhengyuan Liu , Steven D. Schwartz , Demetri Terzopoulos

Diagnosing different retinal diseases from Spectral Domain Optical Coherence Tomography (SD-OCT) images is a challenging task. Different automated approaches such as image processing, machine learning and deep learning algorithms have been…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Sharif Amit Kamran , Sourajit Saha , Ali Shihab Sabbir , Alireza Tavakkoli

Reliable automated analysis of Optical Coherence Tomography (OCT) imaging is crucial for diagnosing retinal disorders but faces a critical barrier: the need for expensive, labor-intensive expert annotations. Supervised deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Tania Haghighi , Sina Gholami , Hamed Tabkhi , Minhaj Nur Alam

The detection of retinal vessel is of great importance in the diagnosis and treatment of many ocular diseases. Many methods have been proposed for vessel detection. However, most of the algorithms neglect the connectivity of the vessels,…

Image and Video Processing · Electrical Eng. & Systems 2019-10-29 Lei Mou , Li Chen , Jun Cheng , Zaiwang Gu , Yitian Zhao , Jiang Liu