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Graph Neural Networks (GNN) exhibit superior performance in graph representation learning, but their inference cost can be high, due to an aggregation operation that can require a memory fetch for a very large number of nodes. This…

Machine Learning · Computer Science 2025-03-18 Yaochen Hu , Mai Zeng , Ge Zhang , Pavel Rumiantsev , Liheng Ma , Yingxue Zhang , Mark Coates

An adaptive scheme to generate reduced-order models for parametric nonlinear dynamical systems is proposed. It aims to automatize the POD-Greedy algorithm combined with empirical interpolation. At each iteration, it is able to adaptively…

Numerical Analysis · Mathematics 2021-10-13 Sridhar Chellappa , Lihong Feng , Peter Benner

Boolean networks (BNs) are important models for gene regulatory networks and many other biological systems. In this paper, we study the minimal controllability problem of threshold and XOR BNs with degree constraints. Firstly, we derive…

Systems and Control · Electrical Eng. & Systems 2025-09-22 Christopher H. Fok , Liangjie Sun , Tatsuya Akutsu , Wai-Ki Ching

Generative models (GMs) such as Generative Adversary Network (GAN) and Variational Auto-Encoder (VAE) have thrived these years and achieved high quality results in generating new samples. Especially in Computer Vision, GMs have been used in…

Machine Learning · Computer Science 2018-04-27 Honggang Zhou , Yunchun Li , Hailong Yang , Wei Li , Jie Jia

Graphs and networks are a key research tool for a variety of science fields, most notably chemistry, biology, engineering and social sciences. Modeling and generation of graphs with efficient sampling is a key challenge for graphs. In…

Machine Learning · Computer Science 2019-09-26 Ruud van Deursen , Guillaume Godin

An algorithm for automated construction of a sparse Bayesian network given an unstructured probabilistic model and causal domain information from an expert has been developed and implemented. The goal is to obtain a network that explicitly…

Artificial Intelligence · Computer Science 2013-04-08 Sampath Srinivas , Stuart Russell , Alice M. Agogino

Bayesian learning of belief networks (BLN) is a method for automatically constructing belief networks (BNs) from data using search and Bayesian scoring techniques. K2 is a particular instantiation of the method that implements a greedy…

Artificial Intelligence · Computer Science 2013-02-28 Constantin F. Aliferis , Gregory F. Cooper

Boolean Networks (BNs) are established models to qualitatively describe biological systems. The analysis of BNs might be infeasible for medium to large BNs due to the state-space explosion problem. We propose a novel reduction technique…

Computational Engineering, Finance, and Science · Computer Science 2021-07-01 Georgios Argyris , Alberto Lluch Lafuente , Mirco Tribastone , Max Tschaikowski , Andrea Vandin

Sparse matrix-matrix multiplication (SpGEMM) is a widely used kernel in various graph, scientific computing and machine learning algorithms. It is well known that SpGEMM is a memory-bound operation, and its peak performance is expected to…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-02-27 Zhixiang Gu , Jose Moreira , David Edelsohn , Ariful Azad

In order to alleviate data sparsity and overfitting problems in maximum likelihood estimation (MLE) for sequence prediction tasks, we propose the Generative Bridging Network (GBN), in which a novel bridge module is introduced to assist the…

Artificial Intelligence · Computer Science 2018-12-03 Wenhu Chen , Guanlin Li , Shuo Ren , Shujie Liu , Zhirui Zhang , Mu Li , Ming Zhou

Adoption of deep neural networks in fields such as economics or finance has been constrained by the lack of interpretability of model outcomes. This paper proposes a generative neural network architecture - the parameter encoder neural…

Machine Learning · Statistics 2021-06-11 Johann Pfitzinger

Gene regulatory networks (GRNs) are increasingly used for explaining biological processes with complex transcriptional regulation. A GRN links the expression levels of a set of genes via regulatory controls that gene products exert on one…

Molecular Networks · Quantitative Biology 2016-06-21 Guy Karlebach

Understanding the complex and stochastic nature of Gene Regulatory Networks (GRNs) remains a central challenge in systems biology. Existing modeling paradigms often struggle to effectively capture the intricate, multi-factor regulatory…

Molecular Networks · Quantitative Biology 2025-08-20 Yiyang Jia , Zheng Wei , Zheng Yang , Guohong Peng

Gene regulatory networks (GRNs) orchestrate cellular decision making and survival strategies. Inferring the structure of these networks from high-dimensional transcriptomics data is a central challenge in systems biology. Traditional…

Applications · Statistics 2025-08-01 Visweswaran Ravikumar , Aaresh Bhathena , Wajd N Al-Holou , Salar Fattahi , Arvind Rao

This paper explores methods for verifying the properties of Binary Neural Networks (BNNs), focusing on robustness against adversarial attacks. Despite their lower computational and memory needs, BNNs, like their full-precision counterparts,…

Machine Learning · Computer Science 2025-04-16 Jianting Yang , Srećko Ðurašinović , Jean-Bernard Lasserre , Victor Magron , Jun Zhao

This article applies Machine Learning techniques to solve Intrusion Detection problems within computer networks. Due to complex and dynamic nature of computer networks and hacking techniques, detecting malicious activities remains a…

Neural and Evolutionary Computing · Computer Science 2009-11-04 Tich Phuoc Tran , Longbing Cao , Dat Tran , Cuong Duc Nguyen

de Bruijn graph-based algorithms are one of the two most widely used approaches for de novo genome assembly. A major limitation of this approach is the large computational memory space requirement to construct the de Bruijn graph, which…

Data Structures and Algorithms · Computer Science 2011-07-11 Chengxi Ye , Zhanshan Sam Ma , Charles H. Cannon , Mihai Pop , Douglas W. Yu

Generative adversarial networks (GANs) are very popular to generate realistic images, but they often suffer from the training instability issues and the phenomenon of mode loss. In order to attain greater diversity in GAN synthesized data,…

Machine Learning · Computer Science 2021-07-13 Blessen George , Vinod K. Kurmi , Vinay P. Namboodiri

This paper proposes a new method to reverse engineer gene regulatory networks from experimental data. The modeling framework used is time-discrete deterministic dynamical systems, with a finite set of states for each of the variables. The…

Quantitative Methods · Quantitative Biology 2007-05-23 Reinhard Laubenbacher , Brandilyn Stigler

Bayesian neural networks (BNNs) are a useful tool for uncertainty quantification, but require substantially more computational resources than conventional neural networks. For non-Bayesian networks, the Lottery Ticket Hypothesis (LTH)…

Machine Learning · Computer Science 2026-02-24 Nicholas Kuhn , Arvid Weyrauch , Lars Heyen , Achim Streit , Markus Götz , Charlotte Debus