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Purpose: The aim of this study was to demonstrate the utility of unsupervised domain adaptation (UDA) in automated knee osteoarthritis (OA) phenotype classification using a small dataset (n=50). Materials and Methods: For this retrospective…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Junru Zhong , Yongcheng Yao , Donal G. Cahill , Fan Xiao , Siyue Li , Jack Lee , Kevin Ki-Wai Ho , Michael Tim-Yun Ong , James F. Griffith , Weitian Chen

Knee osteoarthritis (OA) is a widespread chronic condition that impairs mobility and diminishes quality of life. Despite the proven benefits of exercise therapy and patient education in managing the OA symptoms pain and functional…

Machine Learning · Computer Science 2024-10-17 M. Rafiei , S. Das , M. Bakhtiari , E. M. Roos , S. T. Skou , D. T. Grønne , J. Baumbach , L. Baumbach

Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Ayesha Siddiqua , Rakibul Hasan , Anichur Rahman , Abu Saleh Musa Miah

Degeneration of articular cartilage (AC) is actively studied in knee osteoarthritis (OA) research via magnetic resonance imaging (MRI). Segmentation of AC tissues from MRI data is an essential step in quantification of their damage. Deep…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Egor Panfilov , Aleksei Tiulpin , Stefan Klein , Miika T. Nieminen , Simo Saarakkala

Knee osteoarthritis (OA) is one of the most widespread and burdensome health problems [1-4]. Total knee replacement (TKR) may be offered as treatment for end-stage knee OA. Nevertheless, TKR is an invasive procedure involving prosthesis…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Zhisen Hu , Dominic Cullen , David S. Johnson , Aleksei Tiulpin , Timothy F. Cootes , Claudia Lindner

Diagnosing knee joint osteoarthritis (KOA), a major cause of disability worldwide, is challenging due to subtle radiographic indicators and the varied progression of the disease. Using deep learning for KOA diagnosis requires broad,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Timo Ojala

Knee osteoarthritis (KOA), a common form of arthritis that causes physical disability, has become increasingly prevalent in society. Employing computer-aided techniques to automatically assess the severity and progression of KOA can greatly…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Wenhua Wu , Kun Hu , Wenxi Yue , Wei Li , Milena Simic , Changyang Li , Wei Xiang , Zhiyong Wang

This paper addresses the challenge of localization of anatomical landmarks in knee X-ray images at different stages of osteoarthritis (OA). Landmark localization can be viewed as regression problem, where the landmark position is directly…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Aleksei Tiulpin , Iaroslav Melekhov , Simo Saarakkala

Reliable automated analysis of Optical Coherence Tomography (OCT) imaging is crucial for diagnosing retinal disorders but faces a critical barrier: the need for expensive, labor-intensive expert annotations. Supervised deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Tania Haghighi , Sina Gholami , Hamed Tabkhi , Minhaj Nur Alam

Knee Osteoarthritis (OA) is a common musculoskeletal disorder in the United States. When diagnosed at early stages, lifestyle interventions such as exercise and weight loss can slow OA progression, but at later stages, only an invasive…

Image and Video Processing · Electrical Eng. & Systems 2020-02-26 Aniket A. Tolpadi , Jinhee J. Lee , Valentina Pedoia , Sharmila Majumdar

Bone marrow lesions (BMLs) are critical indicators of knee osteoarthritis (OA). Since they often appear as small, irregular structures with indistinguishable edges in knee magnetic resonance images (MRIs), effective detection of BMLs in MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Shihua Qin , Ming Zhang , Juan Shan , Taehoon Shin , Jonghye Woo , Fangxu Xing

Large numbers of radiographic images are available in knee radiology practices which could be used for training of deep learning models for diagnosis of knee abnormalities. However, those images do not typically contain readily available…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Jikai Zhang , Carlos Santos , Christine Park , Maciej Mazurowski , Roy Colglazier

Knee osteoarthritis (OA) is the most common osteoarthritis and a leading cause of disability. Cartilage defects are regarded as major manifestations of knee OA, which are visible by magnetic resonance imaging (MRI). Thus early detection and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Zixu Zhuang , Liping Si , Sheng Wang , Kai Xuan , Xi Ouyang , Yiqiang Zhan , Zhong Xue , Lichi Zhang , Dinggang Shen , Weiwu Yao , Qian Wang

In this work, we propose an advanced AI based grading system for OCT images. The proposed system is a very deep fully convolutional attentive classification network trained with end to end advanced transfer learning with online random…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Mrinal Haloi

Medical imaging plays a crucial role in assessing knee osteoarthritis (OA) risk by enabling early detection and disease monitoring. Recent machine learning methods have improved risk estimation (i.e., predicting the likelihood of disease…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 David Butler , Adrian Hilton , Gustavo Carneiro

Automated Kellgren--Lawrence (KL) grading from knee radiographs is challenging due to subtle structural changes, long-range anatomical dependencies, and ambiguity near grade boundaries. We propose AGE-Net, a ConvNeXt-based framework that…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Xiaoyang Li , Runni Zhou , Xinghao Yan , Liehao Yan , Zhaochen Li , Chenjie Zhu , Rongrong Fu , Yuan Chai

In recent years the NHS has been having increased difficulty seeing all low-risk patients, this includes but not limited to suspected osteoarthritis (OA) patients. To help address the increased waiting lists and shortages of staff, we…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Kai Armstrong , Lei Zhang , Yan Wen , Alexander P. Willmott , Paul Lee , Xujioing Ye

We present a fully automated learning-based approach for segmenting knee cartilage in the presence of osteoarthritis (OA). The algorithm employs a hierarchical set of two random forest classifiers. The first is a neighborhood approximation…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Ipek Oguz , Honghai Zhang , Milan Sonka

We developed deep learning models for predicting Total Knee Replacement (TKR) need within various time horizons in knee osteoarthritis patients, with a novel capability: the models can perform TKR prediction using a single scan, and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Haresh Rengaraj Rajamohan , Richard Kijowski , Kyunghyun Cho , Cem M. Deniz

Background: Osteoporosis and osteopenia are often undiagnosed until fragility fractures occur. Dual-energy X-ray absorptiometry (DXA) is the reference standard for bone mineral density (BMD) assessment, but access remains limited. Knee…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Zhaochen Li , Xinghao Yan , Runni Zhou , Xiaoyang Li , Chenjie Zhu , Gege Wang , Yu Shi , Lixin Zhang , Rongrong Fu , Liehao Yan , Yuan Chai