Related papers: Semi-Supervised Generative Models for Disease Traj…
Accurately modeling time-continuous stochastic processes from irregular observations remains a significant challenge. In this paper, we leverage ideas from generative modeling of image data to push the boundary of time series generation.…
Rare diseases affect a relatively small number of people, which limits investment in research for treatments and cures. Developing an efficient method for rare disease detection is a crucial first step towards subsequent clinical research.…
Understanding the dynamic nature of biological systems is fundamental to deciphering cellular behavior, developmental processes, and disease progression. Single-cell RNA sequencing (scRNA-seq) has provided static snapshots of gene…
The early identification and intervention of latent depression are of significant societal importance for mental health governance. While current automated detection methods based on social media have shown progress, their decision-making…
Clinical outcome or severity prediction from medical images has largely focused on learning representations from single-timepoint or snapshot scans. It has been shown that disease progression can be better characterized by temporal imaging.…
Background. Alzheimer's disease and related dementia (ADRD) are characterized by multiple and progressive anatomo clinical changes. Yet, modeling changes over disease course from cohort data is challenging as the usual timescales are…
Accurate and reliable forecasting of epidemic incidences is critical for public health preparedness, yet it remains a challenging task due to complex nonlinear temporal dependencies and heterogeneous spatial interactions. Often, point…
Analyzing surgical workflow is crucial for surgical assistance robots to understand surgeries. With the understanding of the complete surgical workflow, the robots are able to assist the surgeons in intra-operative events, such as by giving…
Generative models such as Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs) play an increasingly important role in medical image analysis. The latent spaces of these models often show semantically meaningful…
Despite notable advancements, the integration of deep learning (DL) techniques into impactful clinical applications, particularly in the realm of digital histopathology, has been hindered by challenges associated with achieving robust…
Self-supervised learning (SSL) is attractive for plant disease detection as it can exploit large collections of unlabeled leaf images, yet most existing SSL methods are built on CNNs or vision transformers that are poorly matched to…
In recent years, applying deep learning (DL) to assess structural damages has gained growing popularity in vision-based structural health monitoring (SHM). However, both data deficiency and class-imbalance hinder the wide adoption of DL in…
Generative models can produce synthetic patient records for analytical tasks when real data is unavailable or limited. However, current methods struggle with adhering to domain-specific knowledge and removing invalid data. We present…
Retrieval-augmented generation improves large language models by grounding outputs in external knowledge sources, reducing hallucinations and addressing knowledge cutoffs. However, standard embedding-based retrieval fails to capture the…
Deep generative models trained with large amounts of unlabelled data have proven to be powerful within the domain of unsupervised learning. Many real life data sets contain a small amount of labelled data points, that are typically…
Testing complex simulation models can be expensive and time consuming. Current state-of-the-art methods that explore this problem are fully-supervised; i.e. they require that all examples are labeled. On the other hand, the GenClu system…
Self-supervised learning (SSL) has recently emerged as a powerful approach to learning representations from large-scale unlabeled data, showing promising results in time series analysis. The self-supervised representation learning can be…
Temporal networks are essential for modeling and understanding systems whose behavior varies in time, from social interactions to biological systems. Often, however, real-world data are prohibitively expensive to collect in a large scale or…
High-throughput microarray and sequencing technology have been used to identify disease subtypes that could not be observed otherwise by using clinical variables alone. The classical unsupervised clustering strategy concerns primarily the…
Small longitudinal clinical cohorts, common in maternal health, rare diseases, and early-phase trials, limit computational modeling: too few patients to train reliable models, yet too costly and slow to expand through additional enrollment.…