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Molecular conformation generation, a critical aspect of computational chemistry, involves producing the three-dimensional conformer geometry for a given molecule. Generating molecular conformation via diffusion requires learning to reverse…

Computational Physics · Physics 2023-10-10 Zihan Zhou , Ruiying Liu , Chaolong Ying , Ruimao Zhang , Tianshu Yu

A key question for machine learning approaches in particle physics is how to best represent and learn from collider events. As an event is intrinsically a variable-length unordered set of particles, we build upon recent machine learning…

High Energy Physics - Phenomenology · Physics 2020-04-17 Patrick T. Komiske , Eric M. Metodiev , Jesse Thaler

Object detectors achieve strong performance under nominal imaging conditions but can fail silently when exposed to blur, noise, compression, adverse weather, or resolution changes. In safety-critical settings, it is therefore insufficient…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Stefan Becker , Simon Weiss , Wolfgang Hübner , Michael Arens

Many modern biological assays, including RNA sequencing, yield integer-valued counts that reflect the number of molecules detected. These measurements are often not at the desired resolution: while the unit of interest is typically a single…

Machine Learning · Computer Science 2026-03-06 Nic Fishman , Gokul Gowri , Tanush Kumar , Jiaqi Lu , Valentin de Bortoli , Jonathan S. Gootenberg , Omar Abudayyeh

Predicting molecular conformations from molecular graphs is a fundamental problem in cheminformatics and drug discovery. Recently, significant progress has been achieved with machine learning approaches, especially with deep generative…

Machine Learning · Computer Science 2022-03-16 Minkai Xu , Lantao Yu , Yang Song , Chence Shi , Stefano Ermon , Jian Tang

Improved understanding of charge-transport in single molecules is essential for harnessing the potential of molecules e.g. as circuit components at the ultimate size limit. However, interpretation and analysis of the large, stochastic…

Mesoscale and Nanoscale Physics · Physics 2020-08-06 Nathan D. Bamberger , Jeffrey A. Ivie , Keshaba N. Parida , Dominic V. McGrath , Oliver L. A. Monti

Anomaly detection with convolutional autoencoders is a popular method to search for new physics in a model-agnostic manner. These techniques are powerful, but they are still a "black box," since we do not know what high-level physical…

High Energy Physics - Phenomenology · Physics 2022-09-13 Layne Bradshaw , Spencer Chang , Bryan Ostdiek

Risk assessment is relevant in any workplace, however there is a degree of unpredictability when dealing with flammable or hazardous materials so that detection of fire accidents by itself may not be enough. An example of this is the…

Computer Vision and Pattern Recognition · Computer Science 2022-01-21 Carmina Pérez-Guerrero , Adriana Palacios , Gilberto Ochoa-Ruiz , Christian Mata , Miguel Gonzalez-Mendoza , Luis Eduardo Falcón-Morales

With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

Biomolecules · Quantitative Biology 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

We propose a new approach to train the Generative Adversarial Nets (GANs) with a mixture of generators to overcome the mode collapsing problem. The main intuition is to employ multiple generators, instead of using a single one as in the…

Machine Learning · Computer Science 2017-10-31 Quan Hoang , Tu Dinh Nguyen , Trung Le , Dinh Phung

We describe a technique to learn the underlying structure of collider events directly from the data, without having a particular theoretical model in mind. It allows to infer aspects of the theoretical model that may have given rise to this…

High Energy Physics - Phenomenology · Physics 2020-12-02 Barry M. Dillon , Darius A. Faroughy , Jernej F. Kamenik , Manuel Szewc

Motivated by privacy regulations and the need to mitigate the effects of harmful data, machine unlearning seeks to modify trained models so that they effectively ``forget'' designated data. A key challenge in verifying unlearning is…

Machine Learning · Computer Science 2026-05-05 Rishabh Dixit , Yuan Hui , Rayan Saab

With the advent of future big-data surveys, automated tools for unsupervised discovery are becoming ever more necessary. In this work, we explore the ability of deep generative networks for detecting outliers in astronomical imaging…

In machine learning, accurately predicting the probability that a specific input is correct is crucial for risk management. This process, known as uncertainty (or confidence) estimation, is particularly important in mission-critical…

Machine Learning · Computer Science 2023-01-12 Gabriella Chouraqui , Liron Cohen , Gil Einziger , Liel Leman

This paper proposes a method for estimating and detecting optical signals in practical photon-counting receivers. There are two important aspects of non-perfect photon-counting receivers, namely, (i) dead time which results in blocking…

Signal Processing · Electrical Eng. & Systems 2024-08-21 Chen Wang , Zhiyong Xu , Jingyuan Wang , Jianhua Li , Weifeng Mou , Huatao Zhu , Jiyong Zhao , Yang Su , Yimin Wang , Ailin Qi

Video object segmentation is a fundamental step in many advanced vision applications. Most existing algorithms are based on handcrafted features such as HOG, super-pixel segmentation or texture-based techniques, while recently deep features…

Computer Vision and Pattern Recognition · Computer Science 2018-11-06 Maryam Sultana , Arif Mahmood , Sajid Javed , Soon Ki Jung

Generative models, particularly diffusion models, have made significant success in data synthesis across various modalities, including images, videos, and 3D assets. However, current diffusion models are computationally intensive, often…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Yuanzhi Zhu , Hanshu Yan , Huan Yang , Kai Zhang , Junnan Li

Imaging through scattering media is a challenging problem owing to speckle decorrelations from perturbations in the media itself. For in-line imaging modalities, which are appealing because they are compact, require no moving parts, and are…

Optics · Physics 2022-05-16 Siddharth Rawat , Jonathan Wendoloski , Anna Wang

As a revolutionary generative paradigm of deep learning, generative adversarial networks (GANs) have been widely applied in various fields to synthesize realistic data. However, it is challenging for conventional GANs to synthesize raw…

Signal Processing · Electrical Eng. & Systems 2023-06-27 Weidong Wang , Jiancheng An , Hongshu Liao , Lu Gan , Chau Yuen

The task of deducing three-dimensional molecular configurations from their two-dimensional graph representations holds paramount importance in the fields of computational chemistry and pharmaceutical development. The rapid advancement of…

Biomolecules · Quantitative Biology 2025-01-09 Bobin Yang , Jie Deng , Zhenghan Chen , Ruoxue Wu