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Generative AI presents chemists with novel ideas for drug design and facilitates the exploration of vast chemical spaces. Diffusion models (DMs), an emerging tool, have recently attracted great attention in drug R\&D. This paper…

Biomolecules · Quantitative Biology 2025-07-14 Peining Zhang , Daniel Baker , Minghu Song , Jinbo Bi

Generative modeling has recently seen many exciting developments with the advent of deep generative architectures such as Variational Auto-Encoders (VAE) or Generative Adversarial Networks (GAN). The ability to draw synthetic i.i.d.…

Machine Learning · Computer Science 2021-02-19 Johan Leduc , Nicolas Grislain

Deep generative models open new avenues for simulating realistic genomic data while preserving privacy and addressing data accessibility constraints. While previous studies have primarily focused on generating gene expression or haplotype…

Genomics · Quantitative Biology 2025-08-14 Sihan Xie , Thierry Tribout , Didier Boichard , Blaise Hanczar , Julien Chiquet , Eric Barrey

Modern machine learning techniques, such as deep neural networks, are transforming many disciplines ranging from image recognition to language understanding, by uncovering patterns in big data and making accurate predictions. They have also…

Machine Learning · Computer Science 2021-03-11 Amin Heyrani Nobari , Muhammad Fathy Rashad , Faez Ahmed

Deep generative models (DGMs) have the potential to revolutionize diagnostic imaging. Generative adversarial networks (GANs) are one kind of DGM which are widely employed. The overarching problem with deploying GANs, and other DGMs, in any…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Rucha Deshpande , Mark A. Anastasio , Frank J. Brooks

Deep generative models (DGMs) are effective on learning multilayered representations of complex data and performing inference of input data by exploring the generative ability. However, little work has been done on examining or empowering…

Machine Learning · Computer Science 2015-12-16 Chongxuan Li , Jun Zhu , Tianlin Shi , Bo Zhang

The generation and completion of 3D objects represent a transformative challenge in computer vision. Generative Adversarial Networks (GANs) have recently demonstrated strong potential in synthesizing realistic visual data. However, they…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yahia Hamdi , Nicolas Andrialovanirina , Kélig Mahé , Emilie Poisson Caillault

Designing new chemical compounds with desired pharmaceutical properties is a challenging task and takes years of development and testing. Still, a majority of new drugs fail to prove efficient. Recent success of deep generative modeling…

Machine Learning · Computer Science 2021-09-15 Karina Zadorozhny , Lada Nuzhna

Generative systems have a significant potential to synthesize innovative design alternatives. Still, most of the common systems that have been adopted in design require the designer to explicitly define the specifications of the procedures…

Machine Learning · Computer Science 2019-04-03 Ardavan Bidgoli , Pedro Veloso

Generative AI is transforming image synthesis, enabling the creation of high-quality, diverse, and photorealistic visuals across industries like design, media, healthcare, and autonomous systems. Advances in techniques such as…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Fouad Bousetouane

In many applications of computer graphics, art and design, it is desirable for a user to provide intuitive non-image input, such as text, sketch, stroke, graph or layout, and have a computer system automatically generate photo-realistic…

Computer Vision and Pattern Recognition · Computer Science 2021-10-04 Yuan Xue , Yuan-Chen Guo , Han Zhang , Tao Xu , Song-Hai Zhang , Xiaolei Huang

Deep generative models have unlocked another profound realm of human creativity. By capturing and generalizing patterns within data, we have entered the epoch of all-encompassing Artificial Intelligence for General Creativity (AIGC).…

Artificial Intelligence · Computer Science 2023-12-27 Hanqun Cao , Cheng Tan , Zhangyang Gao , Yilun Xu , Guangyong Chen , Pheng-Ann Heng , Stan Z. Li

Image generation has advanced rapidly over the past decade, yet the literature seems fragmented across different models and application domains. This paper aims to offer a comprehensive survey of breakthrough image generation models,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Rouzbeh Shirvani

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

In recent years the scientific community has devoted much effort in the development of deep learning models for the generation of new molecules with desirable properties (i.e. drugs). This has produced many proposals in literature. However,…

Machine Learning · Computer Science 2020-08-24 Davide Rigoni , Nicolò Navarin , Alessandro Sperduti

Current performance-driven building design methods are not widely adopted outside the research field for several reasons that make them difficult to integrate into a typical design process. In the early design phase, in particular, the…

Machine Learning · Computer Science 2022-04-19 Spyridon Ampanavos , Ali Malkawi

With the rapid development of Generative Artificial Intelligence (GAI) technology, Generative Diffusion Models (GDMs) have shown significant empowerment potential in the field of wireless networks due to advantages, such as noise…

Signal Processing · Electrical Eng. & Systems 2026-03-04 Dayu Fan , Rui Meng , Xiaodong Xu , Yiming Liu , Guoshun Nan , Chenyuan Feng , Shujun Han , Song Gao , Bingxuan Xu , Dusit Niyato , Tony Q. S. Quek , Ping Zhang

Design inspiration is crucial for establishing the direction of a design as well as evoking feelings and conveying meanings during the conceptual design process. Many practice designers use text-based searches on platforms like Pinterest to…

Human-Computer Interaction · Computer Science 2024-07-18 Ye Wang , Nicole B. Damen , Thomas Gale , Voho Seo , Hooman Shayani

Probabilistic graphical modeling (PGM) provides a framework for formulating an interpretable generative process of data and expressing uncertainty about unknowns, but it lacks flexibility. Deep learning (DL) is an alternative framework for…

Machine Learning · Statistics 2021-04-27 Adji B. Dieng

Deep neural networks are commonly used for medical purposes such as image generation, segmentation, or classification. Besides this, they are often criticized as black boxes as their decision process is often not human interpretable.…

Machine Learning · Computer Science 2022-03-22 Jana Fragemann , Lynton Ardizzone , Jan Egger , Jens Kleesiek