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Deep learning has shown remarkable performance in integrating multimodal data for survival prediction. However, existing multimodal methods mainly focus on single cancer types and overlook the challenge of generalization across cancers. In…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Jia-Xuan Jiang , Jiashuai Liu , Hongtao Wu , Yifeng Wu , Zhong Wang , Qi Bi , Yefeng Zheng

While many machine learning methods have been used for medical prediction and risk factor analysis on healthcare data, most prior research has involved single-task learning (STL) methods. However, healthcare research often involves multiple…

Machine Learning · Computer Science 2021-03-08 Lu Wang , Haoyan Jiang , Mark Chignell

Quantitative, volumetric analysis of Magnetic Resonance Imaging (MRI) is a fundamental way researchers study the brain in a host of neurological conditions including normal maturation and aging. Despite the availability of open-source brain…

Quantitative Methods · Quantitative Biology 2019-11-15 Aakash Kaku , Chaitra V. Hegde , Jeffrey Huang , Sohae Chung , Xiuyuan Wang , Matthew Young , Alireza Radmanesh , Yvonne W. Lui , Narges Razavian

Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…

Medical Physics · Physics 2024-12-02 Sangwook Kim , Aly Khalifa , Thomas G. Purdie , Chris McIntosh

Digital breast tomosynthesis (DBT) is now the standard of care for breast cancer screening in the USA. Accurate segmentation of fibroglandular tissue in DBT images is essential for personalized risk estimation, but algorithm development is…

Kernel techniques are among the most popular and flexible approaches in data science allowing to represent probability measures without loss of information under mild conditions. The resulting mapping called mean embedding gives rise to a…

Machine Learning · Statistics 2024-11-27 Linda Chamakh , Zoltan Szabo

We introduce a new class of multilevel, adaptive, dual-space methods for computing fast convolutional transforms. These methods can be applied to a broad class of kernels, from the Green's functions for classical partial differential…

Numerical Analysis · Mathematics 2023-09-12 Shidong Jiang , Leslie Greengard

When developing Computer Aided Detection (CAD) systems for Digital Breast Tomosynthesis (DBT), the complexity arising from the volumetric nature of the modality poses significant technical challenges for obtaining large-scale accurate…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Laurent Dillard , Hyeonsoo Lee , Weonsuk Lee , Tae Soo Kim , Ali Diba , Thijs Kooi

Pretraining on large-scale datasets can boost the performance of object detectors while the annotated datasets for object detection are hard to scale up due to the high labor cost. What we possess are numerous isolated filed-specific…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Jing Hao , Song Chen , Xiaodi Wang , Shumin Han

Background: Accurate deformable image registration (DIR) is required for contour propagation and dose accumulation in MR-guided adaptive radiotherapy (MRgART). This study trained and evaluated a deep learning DIR method for domain invariant…

Huge amount of data is the key of the success of deep learning, however, redundant information impairs the generalization ability of the model and increases the burden of calculation. Dataset Distillation (DD) compresses the original…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Hangyang Kong , Wenbo Zhou , Xuxiang He , Xiaotong Tu , Xinghao Ding

Deep learning models (DLMs) can achieve state-of-the-art performance in histopathology image segmentation and classification, but have limited deployment potential in real-world clinical settings. Uncertainty estimates of DLMs can increase…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Audrey Xie , Elhoucine Elfatimi , Sambuddha Ghosal , Pratik Shah

Cell instance segmentation in cytology images has significant importance for biology analysis and cancer screening, while remains challenging due to 1) the extensive overlapping translucent cell clusters that cause the ambiguous boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Hao Jiang , Rushan Zhang , Yanning Zhou , Yumeng Wang , Hao Chen

Predicting drug-target binding affinity (DTA) is essential for identifying potential therapeutic candidates in drug discovery. However, most existing models rely heavily on static protein structures, often overlooking the dynamic nature of…

Robotics · Computer Science 2025-05-20 Dan Luo , Jinyu Zhou , Le Xu , Sisi Yuan , Xuan Lin

Dose escalation radiotherapy allows increased control of prostate cancer (PCa) but requires segmentation of dominant index lesions (DIL), motivating the development of automated methods for fast, accurate, and consistent segmentation of PCa…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Josiah Simeth , Jue Jiang , Anton Nosov , Andreas Wibmer , Michael Zelefsky , Neelam Tyagi , Harini Veeraraghavan

Decision tree (DT) attracts persistent research attention due to its impressive empirical performance and interpretability in numerous applications. However, the growth of traditional yet widely-used univariate decision trees (UDTs) is…

Machine Learning · Computer Science 2022-06-22 Dan Li , Songcan Chen

We propose a new semi-supervised learning method on face-related tasks based on Multi-Task Learning (MTL) and data distillation. The proposed method exploits multiple datasets with different labels for different-but-related tasks such as…

Computer Vision and Pattern Recognition · Computer Science 2019-07-10 Sepidehsadat Hosseini , Mohammad Amin Shabani , Nam Ik Cho

It is crucial to provide compatible treatment schemes for a disease according to various symptoms at different stages. However, most classification methods might be ineffective in accurately classifying a disease that holds the…

Machine Learning · Computer Science 2019-11-26 Jianguo Chen , Kenli Li , Huigui Rong , Kashif Bilal , Nan Yang , Keqin Li

Breast cancer's complexity and variability pose significant challenges in understanding its progression and guiding effective treatment. This study aims to integrate protein sequence data with expression levels to improve the molecular…

Biomolecules · Quantitative Biology 2025-10-31 Hossein Sholehrasa , Majid Jaberi-Douraki

Since medical image data sets contain few samples and singular features, lesions are viewed as highly similar to other tissues. The traditional neural network has a limited ability to learn features. Even if a host of feature maps is…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Hongfeng You , Long Yu , Shengwei Tian , Xiang Ma , Yan Xing , Xiaojie Ma