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Related papers: PFPs: Prompt-guided Flexible Pathological Segmenta…

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Current medical image analysis systems are typically task-specific, requiring separate models for classification and segmentation, and lack the flexibility to support user-defined workflows. To address these challenges, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Shadman Sobhan , Kazi Abrar Mahmud , Abduz Zami

Foundation models have taken over natural language processing and image generation domains due to the flexibility of prompting. With the recent introduction of the Segment Anything Model (SAM), this prompt-driven paradigm has entered image…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Saikat Roy , Tassilo Wald , Gregor Koehler , Maximilian R. Rokuss , Nico Disch , Julius Holzschuh , David Zimmerer , Klaus H. Maier-Hein

The clinical utility of deep learning models for medical image segmentation is severely constrained by their inability to generalize to unseen domains. This failure is often rooted in the models learning spurious correlations between…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Tao Tang , Shijie Xu , Jionglong Su , Zhixiang Lu

Large-scale vision-language models (VLMs), trained on extensive datasets of image-text pairs, exhibit strong multimodal understanding capabilities by implicitly learning associations between textual descriptions and image regions. This…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Mir Rayat Imtiaz Hossain , Mennatullah Siam , Leonid Sigal , James J. Little

Recent advances in pre-trained Vision Language Models (VLM) have shown promising potential for effectively adapting to downstream tasks through prompt learning, without the need for additional annotated paired datasets. To supplement the…

Machine Learning · Computer Science 2025-07-11 Sua Lee , Kyubum Shin , Jung Ho Park

Large Vision-Language Models offer a new paradigm for AI-driven image understanding, enabling models to perform tasks without task-specific training. This flexibility holds particular promise across medicine, where expert-annotated data is…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Anita Rau , Mark Endo , Josiah Aklilu , Jaewoo Heo , Khaled Saab , Alberto Paderno , Jeffrey Jopling , F. Christopher Holsinger , Serena Yeung-Levy

Current methods for developing foundation models in medical image segmentation rely on two primary assumptions: a fixed set of classes and the immediate availability of a substantial and diverse training dataset. However, this can be…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Xiaoyang Chen , Hao Zheng , Yifang Xie , Yuncong Ma , Tengfei Li

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Promptable Foundation Models (FMs), initially introduced for natural image segmentation, have also revolutionized medical image segmentation. The increasing number of models, along with evaluations varying in datasets, metrics, and compared…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Caroline Magg , Maaike A. ter Wee , Johannes G. G. Dobbe , Geert J. Streekstra , Leendert Blankevoort , Clara I. Sánchez , Hoel Kervadec

The ability to segment objects based on open-ended language prompts remains a critical challenge, requiring models to ground textual semantics into precise spatial masks while handling diverse and unseen categories. We present OpenWorldSAM,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Shiting Xiao , Rishabh Kabra , Yuhang Li , Donghyun Lee , Joao Carreira , Priyadarshini Panda

Recently, large vision model, Segment Anything Model (SAM), has revolutionized the computer vision field, especially for image segmentation. SAM presented a new promptable segmentation paradigm that exhibit its remarkable zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Chenglong Wang , Dexuan Li , Sucheng Wang , Chengxiu Zhang , Yida Wang , Yun Liu , Guang Yang

Current multi-instance learning algorithms for pathology image analysis often require a substantial number of Whole Slide Images for effective training but exhibit suboptimal performance in scenarios with limited learning data. In clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Linhao Qu , Dingkang Yang , Dan Huang , Qinhao Guo , Rongkui Luo , Shaoting Zhang , Xiaosong Wang

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Zhe Xu , Ziyi Liu , Junlin Hou , Jiabo Ma , Cheng Jin , Yihui Wang , Zhixuan Chen , Zhengyu Zhang , Fuxiang Huang , Zhengrui Guo , Fengtao Zhou , Yingxue Xu , Xi Wang , Ronald Cheong Kin Chan , Li Liang , Hao Chen

Language promptable X-ray image segmentation would enable greater flexibility for human-in-the-loop workflows in diagnostic and interventional precision medicine. Prior efforts have contributed task-specific models capable of solving…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Benjamin D. Killeen , Liam J. Wang , Blanca Inigo , Han Zhang , Mehran Armand , Russell H. Taylor , Greg Osgood , Mathias Unberath

Accurate segmentation of lesions plays a critical role in medical image analysis and diagnosis. Traditional segmentation approaches that rely solely on visual features often struggle with the inherent uncertainty in lesion distribution and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-03 Dandan Shan , Zihan Li , Yunxiang Li , Qingde Li , Jie Tian , Qingqi Hong

Medical image segmentation is a vital healthcare endeavor requiring precise and efficient models for appropriate diagnosis and treatment. Vision transformer (ViT)-based segmentation models have shown great performance in accomplishing this…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Numan Saeed , Muhammad Ridzuan , Roba Al Majzoub , Mohammad Yaqub

Foundation models such as Segment Anything Model 3 (SAM3) enable flexible text-guided medical image segmentation, yet their predictions remain highly sensitive to prompt formulation. Even semantically equivalent descriptions can yield…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yonghuang Wu , Zhenyang Liang , Wenwen Zeng , Xuan Xie , Jinhua Yu

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

This paper proposes LLaFS, the first attempt to leverage large language models (LLMs) in few-shot segmentation. In contrast to the conventional few-shot segmentation methods that only rely on the limited and biased information from the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Lanyun Zhu , Tianrun Chen , Deyi Ji , Jieping Ye , Jun Liu

Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhongyi Shui , Yunlong Zhang , Kai Yao , Chenglu Zhu , Sunyi Zheng , Jingxiong Li , Honglin Li , Yuxuan Sun , Ruizhe Guo , Lin Yang