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Building virtual cells with generative models to simulate cellular behavior in silico is emerging as a promising paradigm for accelerating drug discovery. However, prior image-based generative approaches can produce implausible cell images…

Machine Learning · Computer Science 2026-05-22 Dongxia Wu , Shiye Su , Yuhui Zhang , Elaine Sui , Emma Lundberg , Emily B. Fox , Serena Yeung-Levy

We present a modular approach to \emph{reinforcement learning} (RL) in environments consisting of simpler components evolving in parallel. A monolithic view of such modular environments may be prohibitively large to learn, or may require…

Machine Learning · Computer Science 2023-12-18 Milad Kazemi , Mateo Perez , Fabio Somenzi , Sadegh Soudjani , Ashutosh Trivedi , Alvaro Velasquez

Offline reinforcement learning (RL) methods strike a balance between exploration and exploitation by conservative value estimation -- penalizing values of unseen states and actions. Model-free methods penalize values at all unseen actions,…

Machine Learning · Computer Science 2023-09-26 Nirbhay Modhe , Qiaozi Gao , Ashwin Kalyan , Dhruv Batra , Govind Thattai , Gaurav Sukhatme

In recent years, reinforcement learning (RL) systems with general goals beyond a cumulative sum of rewards have gained traction, such as in constrained problems, exploration, and acting upon prior experiences. In this paper, we consider…

Machine Learning · Computer Science 2020-07-07 Junyu Zhang , Alec Koppel , Amrit Singh Bedi , Csaba Szepesvari , Mengdi Wang

Many imitation learning (IL) algorithms use inverse reinforcement learning (IRL) to infer a reward function that aligns with the demonstration. However, the inferred reward functions often fail to capture the underlying task objectives. In…

Machine Learning · Computer Science 2024-11-01 Weichao Zhou , Wenchao Li

With the implementation of reinforcement learning (RL) algorithms, current state-of-art autonomous vehicle technology have the potential to get closer to full automation. However, most of the applications have been limited to game domains…

Robotics · Computer Science 2020-01-14 Wenhui Huang , Francesco Braghin , Zhuo Wang

Inverse Reinforcement Learning (IRL) aims to facilitate a learner's ability to imitate expert behavior by acquiring reward functions that explain the expert's decisions. Regularized IRL applies strongly convex regularizers to the learner's…

Machine Learning · Computer Science 2020-12-04 Wonseok Jeon , Chen-Yang Su , Paul Barde , Thang Doan , Derek Nowrouzezahrai , Joelle Pineau

Humans leverage rich internal models of the world to reason about the future, imagine counterfactuals, and adapt flexibly to new situations. In Reinforcement Learning (RL), world models aim to capture how the environment evolves in response…

Artificial Intelligence · Computer Science 2025-10-29 Léopold Maytié , Roland Bertin Johannet , Rufin VanRullen

As the demand for mobile robots continues to increase, social navigation has emerged as a critical task, driving active research into deep reinforcement learning (RL) approaches. However, because pedestrian dynamics and social conventions…

Robotics · Computer Science 2026-04-10 Haruto Nagahisa , Kohei Matsumoto , Yuki Tomita , Yuki Hyodo , Ryo Kurazume

Multi-Objective Reinforcement Learning (MORL) is a generalization of traditional Reinforcement Learning (RL) that aims to optimize multiple, often conflicting objectives simultaneously rather than focusing on a single reward. This approach…

Machine Learning · Computer Science 2025-08-15 Davide Guidobene , Lorenzo Benedetti , Diego Arapovic

Inverse reinforcement learning (IRL) is computationally challenging, with common approaches requiring the solution of multiple reinforcement learning (RL) sub-problems. This work motivates the use of potential-based reward shaping to reduce…

Machine Learning · Computer Science 2023-12-19 Lauren H. Cooke , Harvey Klyne , Edwin Zhang , Cassidy Laidlaw , Milind Tambe , Finale Doshi-Velez

Approaches for goal-conditioned reinforcement learning (GCRL) often use learned state representations to extract goal-reaching policies. Two frameworks for representation structure have yielded particularly effective GCRL algorithms: (1)…

Machine Learning · Computer Science 2025-12-03 Vivek Myers , Bill Chunyuan Zheng , Benjamin Eysenbach , Sergey Levine

Real-world reinforcement learning (RL) environments, whether in robotics or industrial settings, often involve non-visual observations and require not only efficient but also reliable and thus interpretable and flexible RL approaches. To…

Machine Learning · Computer Science 2024-02-19 Moritz Lange , Noah Krystiniak , Raphael C. Engelhardt , Wolfgang Konen , Laurenz Wiskott

The primary obstacle for applying reinforcement learning (RL) to real-world robotics is the design of effective reward functions. While recently learning-based Process Reward Models (PRMs) are a promising direction, they are often hindered…

Many sequential decision-making tasks involve optimizing multiple conflicting objectives, requiring policies that adapt to different user preferences. In multi-objective reinforcement learning (MORL), one widely studied approach} addresses…

Machine Learning · Computer Science 2026-04-28 Ying-Tu Chen , Wei Hung , Bing-Shu Wu , Zhang-Wei Hong , Ping-Chun Hsieh

Reinforcement Learning (RL) has emerged as a powerful tool for neural combinatorial optimization, enabling models to learn heuristics that solve complex problems without requiring expert knowledge. Despite significant progress, existing RL…

Machine Learning · Computer Science 2025-05-14 Mingjun Pan , Guanquan Lin , You-Wei Luo , Bin Zhu , Zhien Dai , Lijun Sun , Chun Yuan

Reinforcement Learning (RL) serves as a versatile framework for sequential decision-making, finding applications across diverse domains such as robotics, autonomous driving, recommendation systems, supply chain optimization, biology,…

Machine Learning · Computer Science 2024-08-26 Vaneet Aggarwal , Washim Uddin Mondal , Qinbo Bai

Recent state-of-the-art artificial agents lack the ability to adapt rapidly to new tasks, as they are trained exclusively for specific objectives and require massive amounts of interaction to learn new skills. Meta-reinforcement learning…

Machine Learning · Computer Science 2022-03-23 Zhenshan Bing , Lukas Knak , Fabrice Oliver Robin , Kai Huang , Alois Knoll

Offline reinforcement learning (RL) has emerged as a prevalent and effective methodology for real-world recommender systems, enabling learning policies from historical data and capturing user preferences. In offline RL, reward shaping…

Information Retrieval · Computer Science 2025-07-01 Wenzheng Shu , Yanxiang Zeng , Yongxiang Tang , Teng Sha , Ning Luo , Yanhua Cheng , Xialong Liu , Fan Zhou , Peng Jiang

In recent years, \emph{Reinforcement Learning} (RL) has made remarkable progress, achieving superhuman performance in a wide range of simulated environments. As research moves toward deploying RL in real-world applications, the field faces…