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In this article we address the study of ion charge transport in the biological channels separating the intra and extracellular regions of a cell. The focus of the investigation is devoted to including thermal driving forces in the…

Numerical Analysis · Mathematics 2015-04-24 Riccardo Sacco , Fabio Manganini , Joseph W. Jerome

Voltage-activated ion channels vary randomly between open and closed states, influenced by the membrane potential and other factors. Signal transduction is enhanced by noise in a simple ion channel model. The enhancement occurs in a finite…

Biological Physics · Physics 2007-05-23 Michael J. Barber , Manfred L. Ristig

We investigate mechanisms which could generate transient monopole signals in measuring current source density (CSD), as it had been indicated to occur in recent small volume experiments. A simple model is defined for this purpose. It is…

Biological Physics · Physics 2014-10-02 Alejandro Cabo , Jorge J. Riera

We consider a stochastic Hodgkin-Huxley model driven by a periodic signal as model for the membrane potential of a pyramidal neuron. The associated five dimensional diffusion process is a time inhomogeneous highly degenerate diffusion for…

Probability · Mathematics 2012-07-03 Reinhard Höpfner , Eva Löcherbach , Michèle Thieullen

We revisit the classical problem of liquid imbibition in a single pore with spatially varying wettability. Starting from the Lucas-Washburn equation, we derive analytical solutions for the imbibition time (crossing time) in systems where…

Fluid Dynamics · Physics 2026-01-13 Mathis Fricke , Lisanne Gossel , Joel De Coninck

A unified electrodynamic approach to the guided-wave excitation theory is generalized to the waveguiding structures containing a hypothetical space-dispersive medium with drifting charge carriers possessing simultaneously elastic,…

Classical Physics · Physics 2009-10-31 A. A. Barybin

The phase behaviour and dynamics of molecular ionic liquids are studied using primitive models and extensive computer simulations. The models account for size disparity between cation and anion, charge location on the cation, and…

Soft Condensed Matter · Physics 2012-02-23 G. C. Ganzenmüller , P. J. Camp

We revisit the classical problem of diffusion-limited ion transport to a membrane (or electrode) by considering the effects of charged side walls. Using simple mathematical models and numerical simulations, we identify three basic…

Fluid Dynamics · Physics 2015-05-30 E. Victoria Dydek , Boris Zaltzman , Isaak Rubinstein , D. S. Deng , Ali Mani , Martin Z. Bazant

Diffusion-driven flow is a boundary layer flow arising from the interplay of gravity and diffusion in density-stratified fluids when a gravitational field is non-parallel to an impermeable solid boundary. This study investigates…

Fluid Dynamics · Physics 2024-09-23 Lingyun Ding

We study compressible fluid flow in narrow two-dimensional channels using a novel molecular dynamics simulation method. In the simulation area, an upstream source is maintained at constant density and temperature while a downstream…

Condensed Matter · Physics 2009-10-22 M. Sun , C. Ebner

Results of forward modelling of acoustic wave propagation in a realistic solar sub-photosphere with two cases of steady horizontal flows are presented and analysed by the means of local helioseismology. The simulations are based on fully…

Astrophysics · Physics 2009-11-13 S. Shelyag , R. Erdelyi , M. J. Thompson

We perform experimental investigations of osmotically driven flows in artificial microchannels by studying the dynamics and structure of the front of a sugar solution traveling in 200 um wide and 50-200 um deep microchannels. We find that…

Fluid Dynamics · Physics 2008-10-29 Kaare Hartvig Jensen , Jinkee Lee , Tomas Bohr , Henrik Bruus

In this paper I present a first attempt for a possible description of fluids dynamics by mean of a cellular automata technique. With the use of simple and elementary rules, based on random behaviour either, the model permits to obtain the…

Computational Complexity · Computer Science 2007-05-23 Gianluca Argentini

Sequential models like recurrent neural networks and transformers have become standard for probabilistic multivariate time series forecasting across various domains. Despite their strengths, they struggle with capturing high-dimensional…

Machine Learning · Computer Science 2024-10-07 Yu Chen , Marin Biloš , Sarthak Mittal , Wei Deng , Kashif Rasul , Anderson Schneider

This work considers the problem of flow-induced diffusive molecular communication under various mobility conditions such as (i) both transmitter (TX) and receiver (RX) nanomachines are mobile, (ii) TX is mobile and RX is fixed, and (iii) TX…

Information Theory · Computer Science 2018-06-14 Neeraj Varshney , Werner Haselmayr , Weisi Guo

Ion channels selectively transport ions, yet the underlying mechanisms remain elusive. We propose a physical model based on the Driven Damped Harmonic Oscillator (DDHO), where self-organizing turbulent structures in the ionic flow generate…

Biological Physics · Physics 2025-03-05 Ronald L. Westra

The classic Hodgkin-Huxley model is widely used for understanding the electrophysiological dynamics of a single neuron. While applying a constant current to the system results in a single voltage spike, it is possible to produce more…

Quantitative Methods · Quantitative Biology 2021-07-23 Kayleigh Campbell , Laura Staugler , Andrea Arnold

Numerical methods are developed to simulate the wave propagation in heterogeneous 2D fluid / poroelastic media. Wave propagation is described by the usual acoustics equations (in the fluid medium) and by the low-frequency Biot's equations…

Classical Physics · Physics 2012-09-25 Guillaume Chiavassa , Bruno Lombard

We study radio emissions from positive streamers in air using 3D simulations, from which the radiated electric field is computed by solving Jefimenko's equations. The simulations are performed at 0.5 bar using two photoionization methods:…

We investigate the influence of fluid flows on the propagation of chemical fronts arising in FKPP type models. We develop an asymptotic theory for the front speed in a cellular flow in the limit of small molecular diffusivity and fast…

Fluid Dynamics · Physics 2014-07-16 Alexandra Tzella , Jacques Vanneste