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In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Intensive Care Unit (ICU) patients often present with complex, overlapping signs of physiological deterioration that require timely escalation of care. Traditional early warning systems, such as SOFA or MEWS, are limited by their focus on…

The increase in availability of longitudinal electronic health record (EHR) data is leading to improved understanding of diseases and discovery of novel phenotypes. The majority of clustering algorithms focus only on patient trajectories,…

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Predicting time-to-event outcomes in large databases can be a challenging but important task. One example of this is in predicting the time to a clinical outcome for patients in intensive care units (ICUs), which helps to support critical…

Early recognition of risky trajectories during an Intensive Care Unit (ICU) stay is one of the key steps towards improving patient survival. Learning trajectories from physiological signals continuously measured during an ICU stay requires…

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

The pressure of ever-increasing patient demand and budget restrictions make hospital bed management a daily challenge for clinical staff. Most critical is the efficient allocation of resource-heavy Intensive Care Unit (ICU) beds to the…

Initial hours of hospital admission impact clinical trajectory, but early clinical decisions often suffer due to data paucity. With clustering analysis for vital signs within six hours of admission, patient phenotypes with distinct…

The intensive care unit (ICU) manages critically ill patients, many of whom face a high risk of mortality. Early and accurate prediction of in-hospital mortality within the first 24 hours of ICU admission is crucial for timely clinical…

The intensive care unit (ICU) comprises a complex hospital environment, where decisions made by clinicians have a high level of risk for the patients' lives. A comprehensive care pathway must then be followed to reduce p complications.…

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Data mining and machine learning hold great potential to enable health systems to systematically use data and analytics to identify inefficiencies and best practices that improve care and reduce costs. Waveform data offers particularly…

Accurately predicting hospital length-of-stay at the time a patient is admitted to hospital may help guide clinical decision making and resource allocation. In this study we aim to build a decision support system that predicts hospital…

Background: Racial and ethnic minority groups and individuals facing social disadvantages, which often stem from their social determinants of health (SDoH), bear a disproportionate burden of type 2 diabetes (T2D) and its complications. It…

Disparities in access to healthcare have been well-documented in the United States, but their effects on electronic health record (EHR) data reliability and resulting clinical models are poorly understood. Using an All of Us dataset of…

To date, developing a good model for early intensive care unit (ICU) mortality prediction is still challenging. This paper presents a patient based predictive modeling framework (PPMF) to improve the performance of ICU mortality prediction…

Electronic health records (EHR) contain a large variety of information on the clinical history of patients such as vital signs, demographics, diagnostic codes and imaging data. The enormous potential for discovery in this rich dataset is…

Mental disorders impact the lives of millions of people globally, not only impeding their day-to-day lives but also markedly reducing life expectancy. This paper addresses the persistent challenge of predicting mortality in patients with…

The use of machine learning and AI on electronic health records (EHRs) holds substantial potential for clinical insight. However, this approach faces challenges due to data heterogeneity, sparsity, temporal misalignment, and limited labeled…