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This paper presents microwatt end-to-end neural signal processing hardware for deployment-stage real-time upper-limb movement intent decoding. This module features intercellular spike detection, sorting, and decoding operations for a…

Signal Processing · Electrical Eng. & Systems 2020-09-14 Zhewei Jiang , Jiangyi Li , Pavan K. Chundi , Sung Justin Kim , Minhao Yang , Joonseong Kang , Seungchul Jung , Sang Joon Kim , Mingoo Seok

Neural interfaces advance neuroscience research and therapeutic innovations by accurately measuring neuronal activity. However, recording raw data from numerous neurons results in substantial amount of data and poses challenges for wireless…

Recent years have seen an increasing interest in the development of artificial intelligence circuits and systems for edge computing applications. In-memory computing mixed-signal neuromorphic architectures provide promising ultra-low-power…

Emerging Technologies · Computer Science 2021-03-05 Arianna Rubino , Can Livanelioglu , Ning Qiao , Melika Payvand , Giacomo Indiveri

Closed-loop neural interfaces with on-chip machine learning can detect and suppress disease symptoms in neurological disorders or restore lost functions in paralyzed patients. While high-density neural recording can provide rich neural…

Signal Processing · Electrical Eng. & Systems 2023-03-21 Uisub Shin , Cong Ding , Bingzhao Zhu , Yashwanth Vyza , Alix Trouillet , Emilie C. M. Revol , Stéphanie P. Lacour , Mahsa Shoaran

In the application of brain-computer interface (BCI), while pursuing accurate decoding of brain signals, we also need consider the computational efficiency of BCI devices. ECoG signals are multi-channel temporal signals which is collected…

Numerical Analysis · Mathematics 2024-12-24 Changqing Ji , Keisuke Kawasaki , Isao Hasegawa , Takayuki Okatani

Growing evidence suggests that phase-locked deep brain stimulation (DBS) can effectively regulate abnormal brain connectivity in neurological and psychiatric disorders. This letter therefore presents a low-power SoC with both neural…

Systems and Control · Electrical Eng. & Systems 2023-03-21 Uisub Shin , Cong Ding , Virginia Woods , Alik S. Widge , Mahsa Shoaran

Neural networks have proven effective for solving many difficult computational problems. Implementing complex neural networks in software is very computationally expensive. To explore the limits of information processing, it will be…

Neural and Evolutionary Computing · Computer Science 2017-04-20 Jeffrey M. Shainline , Sonia M. Buckley , Richard P. Mirin , Sae Woo Nam

Edge devices equipped with computer vision must deal with vast amounts of sensory data with limited computing resources. Hence, researchers have been exploring different energy-efficient solutions such as near-sensor processing, in-sensor…

Image and Video Processing · Electrical Eng. & Systems 2023-01-24 Md Abdullah-Al Kaiser , Gourav Datta , Zixu Wang , Ajey P. Jacob , Peter A. Beerel , Akhilesh R. Jaiswal

The computational complexity of deep learning algorithms has given rise to significant speed and memory challenges for the execution hardware. In energy-limited portable devices, highly efficient processing platforms are indispensable for…

Understanding the coordinated activity underlying brain computations requires large-scale, simultaneous recordings from distributed neuronal structures at a cellular-level resolution. One major hurdle to design high-bandwidth,…

Neural and Evolutionary Computing · Computer Science 2018-09-18 Tong Wu , Wenfeng Zhao , Edward Keefer , Zhi Yang

This paper describes a highly-integrated CMOS system-on-chip (SoC) for active structural health monitoring (SHM). The chip integrates ultrasonic power and bidirectional half-duplex data transfer, a power management unit (PMU), and an…

Signal Processing · Electrical Eng. & Systems 2021-10-26 Xinyao Tang , Soumyajit Mandal , Tayfun Ozdemir

Conventional spectrometers are limited by trade-offs set by size, cost, signal-to-noise ratio (SNR), and spectral resolution. Here, we demonstrate a deep learning-based spectral reconstruction framework, using a compact and low-cost on-chip…

Stimulation of target neuronal populations using optogenetic techniques during specific sleep stages has begun to elucidate the mechanisms and effects of sleep. To conduct closed-loop optogenetic sleep studies in untethered animals, we…

Neurons and Cognition · Quantitative Biology 2021-08-30 Xilin Liu , Andrew G. Richardson

Extracellular, large scale in vivo recording of neural activity is mandatory for elucidating the interaction of neurons within large neural networks at the level of their single unit activity. Technological achievements in MEMS-based…

Neurons and Cognition · Quantitative Biology 2017-07-03 Patrick Ruther , Oliver Paul

The application of closed-loop approaches in systems neuroscience and therapeutic stimulation holds great promise for revolutionizing our understanding of the brain and for developing novel neuromodulation therapies to restore lost…

Signal Processing · Electrical Eng. & Systems 2021-10-12 Bingzhao Zhu , Uisub Shin , Mahsa Shoaran

As next-generation implantable brain-machine interfaces become pervasive on edge device, incrementally learning new tasks in bio-plasticity ways is urgently demanded for Neuromorphic chips. Due to the inherent characteristics of its…

Emerging Technologies · Computer Science 2023-12-01 Zifan Ning , Chaojin Chen , Xiang Cheng , Wangzi Yao , Tielin Zhang , Bo Xu

A switched-capacitor (SC) neuromorphic system for closed-loop neural coupling in 28 nm CMOS is presented, occupying 600 um by 600 um. It offers 128 input channels (i.e. presynaptic terminals), 8192 synapses and 64 output channels (i.e.…

We introduce a novel electro-optomechanic neural sensor for realizing ultra-compact neural recording probes that can detect and relay electrophysiology signals from within neural tissue. This technology addresses outstanding challenges…

Synaptic dynamics, such as long- and short-term plasticity, play an important role in the complexity and biological realism achievable when running neural networks on a neuromorphic IC. For example, they endow the IC with an ability to…

Spike sorting is a critical process for decoding large-scale neural activity from extracellular recordings. The advancement of neural probes facilitates the recording of a high number of neurons with an increase in channel counts, arising a…

Signal Processing · Electrical Eng. & Systems 2025-01-31 Yuntao Han , Yihan Pan , Xiongfei Jiang , Cristian Sestito , Shady Agwa , Themis Prodromakis , Shiwei Wang
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