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Tractography is a unique method for mapping white matter connections in the brain, but tractography algorithms suffer from an inherent trade-off between sensitivity and specificity that limits accuracy. Incorporating prior knowledge of…

Computational Engineering, Finance, and Science · Computer Science 2025-11-10 Elinor Thompson , Tiantian He , Anna Schroder , Ahmed Abdulaal , Alec Sargood , Sonja Soskic , Henry F. J. Tregidgo , Daniel C. Alexander

In this work, we unveil and study idiosyncrasies in Large Language Models (LLMs) -- unique patterns in their outputs that can be used to distinguish the models. To do so, we consider a simple classification task: given a particular text…

Computation and Language · Computer Science 2025-06-17 Mingjie Sun , Yida Yin , Zhiqiu Xu , J. Zico Kolter , Zhuang Liu

Large Language Models (LLMs) have revolutionized natural language processing tasks, demonstrating their exceptional capabilities in various domains. However, their potential for behavior graph understanding in job recommendations remains…

Artificial Intelligence · Computer Science 2023-12-27 Likang Wu , Zhaopeng Qiu , Zhi Zheng , Hengshu Zhu , Enhong Chen

Algorithm design is crucial for effective problem-solving across various domains. The advent of Large Language Models (LLMs) has notably enhanced the automation and innovation within this field, offering new perspectives and promising…

Machine Learning · Computer Science 2026-01-06 Fei Liu , Yiming Yao , Ping Guo , Zhiyuan Yang , Zhe Zhao , Xi Lin , Xialiang Tong , Kun Mao , Zhichao Lu , Zhenkun Wang , Mingxuan Yuan , Qingfu Zhang

Large language models (LLMs) have recently shown strong reasoning capabilities beyond traditional language tasks, motivating their use for numerical optimization. This paper presents LLMize, an open-source Python framework that enables…

Machine Learning · Computer Science 2026-01-06 M. Rizki Oktavian

We present a novel framework that integrates Large Language Models (LLMs) with automated planning and formal verification to streamline the creation and use of Markov Decision Processes (MDP). Our system leverages LLMs to extract structured…

Robotics · Computer Science 2026-01-12 Enrico Saccon , Davide De Martini , Matteo Saveriano , Edoardo Lamon , Luigi Palopoli , Marco Roveri

Building custom data analysis platforms traditionally requires extensive software engineering expertise, limiting accessibility for many researchers. Here, I demonstrate that modern large language models (LLMs) and autonomous coding agents…

Other Quantitative Biology · Quantitative Biology 2025-10-14 Jesse G. Meyer

Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

Large language models (LLMs) are now available from cloud API providers in various sizes and configurations. While this diversity offers a broad spectrum of choices, effectively leveraging the options to optimize computational cost and…

Large Language Models (LLMs) possess substantial reasoning capabilities and are increasingly applied to optimization tasks, particularly in synergy with evolutionary computation. However, while recent surveys have explored specific aspects…

Neural and Evolutionary Computing · Computer Science 2026-01-08 Yisong Zhang , Ran Cheng , Guoxing Yi , Kay Chen Tan

Large language models (LLMs) are changing the way researchers interact with code and data in scientific computing. While their ability to generate general-purpose code is well established, their effectiveness in producing scientifically…

Software Engineering · Computer Science 2026-05-25 Ethan Holbrook , Juan C. Verduzco , Alejandro Strachan

In the rapidly evolving landscape of genomics, deep learning has emerged as a useful tool for tackling complex computational challenges. This review focuses on the transformative role of Large Language Models (LLMs), which are mostly based…

Search-based test generators are effective at producing unit tests with high coverage. However, such automatically generated tests have no meaningful test and variable names, making them hard to understand and interpret by developers. On…

Software Engineering · Computer Science 2025-06-12 Matteo Biagiola , Gianluca Ghislotti , Paolo Tonella

Large Language Models (LLMs) are increasingly adopted as conversational assistants in genomics, where they are mainly used to reason over biological knowledge, annotations, and analysis outputs through natural language interfaces. However,…

Genomics · Quantitative Biology 2026-04-08 Weicai Long , Yusen Hou , Junning Feng , Houcheng Su , Shuo Yang , Donglin Xie , Yanlin Zhang

In recent years, Large Language Models (LLMs) have emerged as transformative tools across numerous domains, impacting how professionals approach complex analytical tasks. This systematic mapping study comprehensively examines the…

Computers and Society · Computer Science 2025-08-19 Sai Sanjna Chintakunta , Nathalia Nascimento , Everton Guimaraes

Large Language Models (LLMs) have achieved strong performance across a wide range of natural language processing tasks in recent years, including machine translation, text generation, and question answering. As their applications extend to…

Computation and Language · Computer Science 2025-12-30 Xin Zhang , Yang Cao , Baoxing Wu , Xinyi Chen , Kai Song , Siying Li

Large language models (LLMs) have demonstrated remarkable advancements, primarily due to their capabilities in modeling the hidden relationships within text sequences. This innovation presents a unique opportunity in the field of life…

Genomics · Quantitative Biology 2024-12-25 Cong Li , Qingqing Long , Yuanchun Zhou , Meng Xiao

Despite the superior performance of large language models to generate natural language texts, it is hard to generate texts with correct logic according to a given task, due to the difficulties for neural models to capture implied rules from…

Computation and Language · Computer Science 2024-07-08 Fan Zhang , Kebing Jin , Hankz Hankui Zhuo

Large language models (LLMs) have demonstrated immense potential across various tasks. However, research for exploring and improving the capabilities of LLMs in interpreting graph structures remains limited. To address this gap, we conduct…

Computation and Language · Computer Science 2025-02-17 Jie He , Yijun Yang , Wanqiu Long , Deyi Xiong , Victor Gutierrez-Basulto , Jeff Z. Pan

We present a novel benchmark designed to rigorously evaluate the capabilities of large language models (LLMs) in mathematical reasoning and algorithmic code synthesis tasks. The benchmark comprises integer sequence generation tasks sourced…

Machine Learning · Computer Science 2025-11-11 Daniel O'Malley , Manish Bhattarai , Nishath Rajiv Ranasinghe , Erick Draayer , Javier Santos