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Related papers: Microbial and Viral Ecology Analysis for Metagenom…

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Biologists study Diatoms, a fundamental algae, to assess the health of aquatic systems. Diatom specimens have traditionally been preserved on analog slides, where a single slide can contain thousands of these microscopic organisms.…

Information Retrieval · Computer Science 2024-11-04 Kio Polson , Marina Potapova , Uttam Meena , Chad Peiper , Joshua Brown , Joshua Agar , Jane Greenberg

Metagenomics characterizes microbial communities by random shotgun sequencing of DNA isolated directly from an environment of interest. An essential step in computational metagenome analysis is taxonomic sequence assignment, which allows us…

Genomics · Quantitative Biology 2014-04-04 J. Dröge , I. Gregor , A. C. McHardy

This review focuses on microbiomes associated with residues within the context of other microbial habitats in cereal-producing agroecosystems such as phyllosphere or rhizosphere. We connect residue microbiome with the survival of…

Populations and Evolution · Quantitative Biology 2019-08-14 Lydie Kerdraon , Valérie Laval , Frédéric Suffert

Self-organizing complex systems typically are comprised of a large number of frequently similar components or events. Through their process, a pattern at the global-level of a system emerges solely from numerous interactions among the…

Artificial Intelligence · Computer Science 2007-05-23 Vitorino Ramos , Ajith Abraham

Metagenome, a mixture of different genomes (as a rule, bacterial), represents a pattern, and the analysis of its composition is, currently, one of the challenging problems of bioinformatics. In the present study, the possibility of…

Quantitative Methods · Quantitative Biology 2016-11-04 Valery Kirzhner , Zeev Volkovich , Renata Avros , Katerina Korenblat

From soil to the gut, communities composed of thousands of microbes perform functions such as carbon sequestration and immune system regulation. Here, we introduce a data-driven approach that explains how community function can be traced to…

Biological Physics · Physics 2026-03-05 Matthew S Schmitt , Kiseok Lee , Freddy Bunbury , Joseph A Landsittel , Vincenzo Vitelli , Seppe Kuehn

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

Quantitative Methods · Quantitative Biology 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman

The human body consists of microbiomes associated with the development and prevention of several diseases. These microbial organisms form several complex interactions that are informative to the scientific community for explaining disease…

Methodology · Statistics 2024-04-16 Tejasv Bedi , Bencong Zhu , Michael L. Neugent , Kevin C. Lutz , Nicole J. De Nisco , Qiwei Li

The gut microbiome plays a crucial role in human health, yet the mechanisms underlying host-microbiome interactions remain unclear, limiting its translational potential. Recent microbiome multiomics studies, particularly paired…

Methodology · Statistics 2025-04-09 Haoran Shi , Yue Wang , Dan Cheng

There has been a growing acknowledgement of the involvement of the gut microbiome - the collection of microbes that reside in our gut - in regulating our mood and behaviour. This phenomenon is referred to as the microbiome-gut-brain axis.…

Genomics · Quantitative Biology 2023-12-11 Thomaz F. S. Bastiaanssen , Thomas P. Quinn , Amy Loughman

A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences…

Biological Physics · Physics 2019-03-06 Robert Marsland , Wenping Cui , Joshua Goldford , Alvaro Sanchez , Kirill Korolev , Pankaj Mehta

Microbial ecology serves as a foundation for a wide range of scientific and biomedical studies. Rapidly-evolving high-throughput sequencing technology enables the comprehensive search for microbial biomarkers using longitudinal experiments.…

Large-scale perturbations in the microbiome constitution are strongly correlated, whether as a driver or a consequence, with the health and functioning of human physiology. However, understanding the difference in the microbiome profiles of…

Quantitative Methods · Quantitative Biology 2022-09-08 Kateryna Melnyk , Kuba Weimann , Tim O. F. Conrad

Metagenomics enables the reconstruction of microbial genomes in complex microbial communities without the need for culturing. Since assembly typically results in fragmented genomes the grouping of genome fragments (contigs) belonging to the…

16S-ribosomal sequencing and other metagonomic techniques provide snapshots of microbial communities, revealing phylogeny and the abundances of microbial populations across diverse ecosystems. While changes in microbial community structure…

Microbial communities are widely studied using high-throughput sequencing techniques, such as 16S rRNA gene sequencing. These techniques have attracted biologists as they offer powerful tools to explore microbial communities and investigate…

Applications · Statistics 2021-04-06 Elham Bayat Mokhtari , Benjamin Ridenhour

We examine the application of narrative strategies to present a complex and unfamiliar metagenomics dataset to the public in a science museum. Our dataset contains information about microbial gene expressions that scientists use to infer…

Graphics · Computer Science 2023-08-16 Keshav Dasu , Kwan-Liu Ma , Joyce Ma , Jennifer Frazier

The intestinal microbiota plays important roles in digestion and resistance against entero-pathogens. As with other ecosystems, its species composition is resilient against small disturbances but strong perturbations such as antibiotics can…

Quantitative Methods · Quantitative Biology 2015-06-04 Vanni Bucci , Serena Bradde , Giulio Biroli , Joao B. Xavier

Motivation: Accurate data analysis and quality control is critical for metagenomic studies. Though many tools exist to analyze metagenomic data there is no consistent framework to integrate and run these tools across projects. Currently,…

Quantitative Methods · Quantitative Biology 2020-09-28 David C Danko , Chris Mason

The introduction of non-native organisms into complex microbiome communities holds enormous potential to benefit society. However, microbiome engineering faces several challenges including successful establishment of the organism into the…

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