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Recent experiments have elucidated the physical properties of kinetoplasts, which are chain-mail-like structures found in the mitochondria of trypanosome parasites formed from catenated DNA rings. Inspired by these studies, we use Monte…

Soft Condensed Matter · Physics 2021-10-26 James M. Polson , Edgar J. Garcia , Alexander R. Klotz

How frictional effects emerge at the microscopic level in particulate materials remains a challenging question, particularly in systems subject to thermal fluctuations due to the transient nature of interparticle contacts. Here, we directly…

Soft Condensed Matter · Physics 2025-08-12 Berend van der Meer , Taiki Yanagishima , Roel P. A. Dullens

Induced by proteins within the cell membrane or by differential growth, heating, or swelling, spontaneous curvatures can drastically affect the morphology of thin bodies and induce mechanical instabilities. Yet, the interaction of…

Soft Condensed Matter · Physics 2018-01-31 Matteo Pezzulla , Norbert Stoop , Mark P. Steranka , Abdikhalaq J. Bade , Douglas P. Holmes

The structural properties of suspensions and other multiphase systems are vital to overall processability, functionality and acceptance among consumers. Therefore, it is crucial to understand the intrinsic connection between the…

Soft Condensed Matter · Physics 2020-09-24 Sebastian Bindgen , Frank Bossler , Jens Allard , Erin Koos

Self-assembly of protein monomers into distinct membrane protein oligomers provides a general mechanism for diversity in the molecular architectures, and resulting biological functions, of membrane proteins. We develop a general physical…

Biomolecules · Quantitative Biology 2016-11-29 Osman Kahraman , Christoph A. Haselwandter

We consider a system of spherical colloidal particles with a size polydispersity and use a simple van der Waals description in order to study the combined effect of both the polydispersity and the spatial non-uniformity induced by a planar…

Statistical Mechanics · Physics 2009-11-07 L. Bellier-Castella , H. Xu , M. Baus

Due to the cluster reducibility of multiquark operators, a strong interplay exists in tetraquarks between the compact structure, resulting from the direct confining forces acting on quarks and gluons, and the molecular structure, dominated…

High Energy Physics - Phenomenology · Physics 2022-03-11 Hagop Sazdjian

Enzymatic molecules that actively support many cellular processes, including transport, cell division and cell motility, are known as motor proteins or molecular motors. Experimental studies indicate that they interact with each other and…

Biological Physics · Physics 2015-05-20 Daniel Celis-Garza , Hamid Teimouri , Anatoly B. Kolomeisky

Quantum interactions exchanging different types of particles play a pivotal r\^{o}le in quantum many-body theory, but they are not sufficiently investigated from a mathematical perspective. Here, we consider a system made of two fermions…

Mathematical Physics · Physics 2025-06-12 J. -B. Bru , W. de Siqueira Pedra , A. Ramer dos Santos

We investigate the effect of macromolecular crowding on protein folding, using purely repulsive crowding particles and a self-organizing polymer model of protein folding. We find that the thermodynamics of folding for typical alpha-, beta-…

Soft Condensed Matter · Physics 2009-02-27 Jeetain Mittal , Robert B. Best

The conformation and the phase diagram of a membrane protein are investigated via grand canonical ensemble approach using a homopolymer model. We discuss the nature and pathway of $\alpha$-helix integration into the membrane that results…

Soft Condensed Matter · Physics 2009-10-31 Pyeong Jun Park , W. Sung

A broad range of membrane proteins display anomalous diffusion on the cell surface. Different methods provide evidence for obstructed subdiffusion and diffusion on a fractal space, but the underlying structure inducing anomalous diffusion…

Biological Physics · Physics 2017-03-15 Sanaz Sadegh , Jenny L. Higgins , Patrick C. Mannion , Michael M. Tamkun , Diego Krapf

In a system of colloidal inclusions suspended in a thermalized bath of smaller particles, the bath engenders an attractive force between the inclusions, arising mainly from entropic origins, known as the depletion force. In the case of…

Soft Condensed Matter · Physics 2020-10-01 Mahdi Zarif , Ali Naji

We study a simplified model of monoclonal antibodies confined in a patchy random porous medium. Antibodies are represented as Y-shaped particles composed of seven tangential hard spheres with attractive patches on the terminal beads, while…

Soft Condensed Matter · Physics 2026-03-31 Yu. V. Kalyuzhnyi , T. Patsahan

Biological membranes are elastic media in which the presence of a transmembrane protein leads to local bilayer deformation. The energetics of deformation allow two membrane proteins in close proximity to influence each other's equilibrium…

Subcellular Processes · Quantitative Biology 2015-06-26 Tristan Ursell , Kerwyn Huang , Eric Peterson , Rob Phillips

Reaction-diffusion models with nonlocal constraints naturally arise as limiting cases of coupled bulk-surface models of intracellular signalling. In this paper, a minimal, mass-conserving model of cell-polarization on a curved membrane is…

Pattern Formation and Solitons · Physics 2022-10-04 Pearson W. Miller , Daniel Fortunato , Matteo Novaga , Stanislav Y. Shvartsman , Cyrill B. Muratov

We consider multi-chain protein native structures and propose a criterion that determines whether two chains in the system are entangled or not. The criterion is based on the behavior observed by pulling at both temini of each chain…

Biomolecules · Quantitative Biology 2017-07-19 Yani Zhao , Mateusz Chwastyk , Marek Cieplak

Biomolecular condensates play essential roles in cellular processes, and recent efforts have focused on understanding their assembly and rational design principles. In this study, we have employed an explicit-solvent minimal statistical…

Soft Condensed Matter · Physics 2026-05-26 Siddhartha Roy , Rakesh S. Singh

The evolution, regulation and sustenance of biological complexity is determined by protein-protein interaction network that is filled with dynamic events. Recent experimental evidences point out that clustering of proteins has a vital role…

Tissues and Organs · Quantitative Biology 2007-05-23 RV Krishnan

The adhesion of cell membranes is mediated by the binding of membrane-anchored receptor and ligand proteins. In this article, we review recent results from simulations and theory that lead to novel insights on how the binding equilibrium…

Biomolecules · Quantitative Biology 2016-06-15 Thomas R. Weikl , Jinglei Hu , Guang-Kui Xu , Reinhard Lipowsky