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Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Faisal Ahmed

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

Image and Video Processing · Electrical Eng. & Systems 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

Breast cancer is one of the main causes of cancer death worldwide. Early diagnostics significantly increases the chances of correct treatment and survival, but this process is tedious and often leads to a disagreement between pathologists.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Alexander Rakhlin , Alexey Shvets , Vladimir Iglovikov , Alexandr A. Kalinin

Histopathological image analysis is the gold standard to diagnose cancer. Carcinoma is a subtype of cancer that constitutes more than 80% of all cancer cases. Squamous cell carcinoma and adenocarcinoma are two major subtypes of carcinoma,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-20 Swathi Prabhua , Keerthana Prasada , Antonio Robels-Kelly , Xuequan Lu

Lung and Colon cancer are one of the leading causes of mortality and morbidity in adults. Histopathological diagnosis is one of the key components to discern cancer type. The aim of the present research is to propose a computer aided…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Sanidhya Mangal , Aanchal Chaurasia , Ayush Khajanchi

Spatial arrangement of cells of various types, such as tumor infiltrating lymphocytes and the advancing edge of a tumor, are important features for detecting and characterizing cancers. However, convolutional neural networks (CNNs) do not…

Image and Video Processing · Electrical Eng. & Systems 2019-08-15 Shrey Gadiya , Deepak Anand , Amit Sethi

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Eric Cosatto , Kyle Gerard , Hans-Peter Graf , Maki Ogura , Tomoharu Kiyuna , Kanako C. Hatanaka , Yoshihiro Matsuno , Yutaka Hatanaka

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena

Despite great advances, molecular cancer pathology is often limited to the use of a small number of biomarkers rather than the whole transcriptome, partly due to computational challenges. Here, we introduce a novel architecture of Deep…

Machine Learning · Statistics 2019-08-14 Behrooz Azarkhalili , Ali Saberi , Hamidreza Chitsaz , Ali Sharifi-Zarchi

Breast cancer has become one of the most prevalent cancers by which people all over the world are affected and is posed serious threats to human beings, in a particular woman. In order to provide effective treatment or prevention of this…

Image and Video Processing · Electrical Eng. & Systems 2021-07-15 Pouya Hallaj Zavareh , Atefeh Safayari , Hamidreza Bolhasani

Can a single label-free image reveal whether cancer cells were exposed to chemotherapy? We present an innovative methodology on the label-free and high-resolution imaging properties of phase holotomographic microscopy coupled with neural…

Biopsies are the gold standard for breast cancer diagnosis. This task can be improved by the use of Computer Aided Diagnosis (CAD) systems, reducing the time of diagnosis and reducing the inter and intra-observer variability. The advances…

Computer Vision and Pattern Recognition · Computer Science 2019-05-30 Jonathan de Matos , Alceu de S. Britto , Luiz E. S. de Oliveira , Alessandro L. Koerich

The task of multimodal cancer detection is to determine the locations and categories of lesions by using different imaging techniques, which is one of the key research methods for cancer diagnosis. Recently, deep learning-based object…

Image and Video Processing · Electrical Eng. & Systems 2023-12-06 Yan Tian , Zhaocheng Xu , Yujun Ma , Weiping Ding , Ruili Wang , Zhihong Gao , Guohua Cheng , Linyang He , Xuran Zhao

The problem of recognizing various types of tissues present in multi-gigapixel histology images is an important fundamental pre-requisite for downstream analysis of the tumor microenvironment in a bottom-up analysis paradigm for…

Image and Video Processing · Electrical Eng. & Systems 2021-04-02 Nima Hatami , Mohsin Bilal , Nasir Rajpoot

Deep learning has shown promising results in medical image analysis, however, the lack of very large annotated datasets confines its full potential. Although transfer learning with ImageNet pre-trained classification models can alleviate…

Computer Vision and Pattern Recognition · Computer Science 2018-08-16 Ken C. L. Wong , Tanveer Syeda-Mahmood , Mehdi Moradi

Breast cancer is one of the main causes of death worldwide. Histopathological cellularity assessment of residual tumors in post-surgical tissues is used to analyze a tumor's response to a therapy. Correct cellularity assessment increases…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Alexander Rakhlin , Aleksei Tiulpin , Alexey A. Shvets , Alexandr A. Kalinin , Vladimir I. Iglovikov , Sergey Nikolenko

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr

Recent advances in machine learning are transforming medical image analysis, particularly in cancer detection and classification. Techniques such as deep learning, especially convolutional neural networks (CNNs) and vision transformers…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Arezoo Borji , Gernot Kronreif , Bernhard Angermayr , Sepideh Hatamikia