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Spatial Transcriptomics (ST) provides spatially-resolved gene expression, offering crucial insights into tissue architecture and complex diseases. However, its prohibitive cost limits widespread adoption, leading to significant attention on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Taejin Jeong , Joohyeok Kim , Jinyeong Kim , Chanyoung Kim , Seong Jae Hwang

Operator eigenvalue problems play a critical role in various scientific fields and engineering applications, yet numerical methods are hindered by the curse of dimensionality. Recent deep learning methods provide an efficient approach to…

Machine Learning · Computer Science 2025-10-29 Hong Wang , Jiang Yixuan , Jie Wang , Xinyi Li , Jian Luo , Huanshuo Dong

Transformers have gained increasing popularity in a wide range of applications, including Natural Language Processing (NLP), Computer Vision and Speech Recognition, because of their powerful representational capacity. However, harnessing…

Mapping spatial distributions of transcriptomic cell types is essential to understanding the brain, with its exceptional cellular heterogeneity and the functional significance of its spatial organization. Spatial transcriptomics techniques…

Neurons and Cognition · Quantitative Biology 2023-01-23 Brian Long , Jeremy Miller , The SpaceTx Consortium

Transformer models have consistently achieved remarkable results in various domains such as natural language processing and computer vision. However, despite ongoing research efforts to better understand these models, the field still lacks…

Machine Learning · Computer Science 2024-10-18 Ilya Kaufman , Omri Azencot

Multivariate long-term time series forecasting is of great application across many domains, such as energy consumption and weather forecasting. With the development of transformer-based methods, the performance of multivariate long-term…

Machine Learning · Computer Science 2023-05-29 Zheng Sun , Yi Wei , Wenxiao Jia , Long Yu

Spatio-temporal processes often exhibit highly heterogeneous and non-intuitive responses to localized disruptions, limiting the effectiveness of conventional message passing approaches in modeling local heterogeneity. We reformulate…

Machine Learning · Computer Science 2026-04-21 Abeer Mostafa , Raneen Younis , Zahra Ahmadi

Local feature matching between images remains a challenging task, especially in the presence of significant appearance variations, e.g., extreme viewpoint changes. In this work, we propose DeepMatcher, a deep Transformer-based network built…

Computer Vision and Pattern Recognition · Computer Science 2023-01-10 Tao Xie , Kun Dai , Ke Wang , Ruifeng Li , Lijun Zhao

Deep learning has shown substantial progress in image analysis. However, the computational demands of large, fully trained models remain a consideration. Transfer learning offers a strategy for adapting pre-trained models to new tasks.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Jacinto Colan , Ana Davila , Yasuhisa Hasegawa

Single-cell-resolution spatial transcriptomics profiles gene expression at cellular locations in native tissues, yet accurate cell-type annotation remains challenging: imaging-based platforms are constrained by targeted gene panels, whereas…

Cell Behavior · Quantitative Biology 2026-05-27 Yiyang Zhang , Bokai Zhao , Xiaoru Zhang , Zongchang Du , Xiaojuan Sun , Tianzi Jiang

Spatial transcriptomics (ST) reveals spatial heterogeneity of gene expression, yet its resolution is limited by current platforms. Recent methods enhance resolution via H&E-stained histology, but three major challenges persist: (1)…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Xuepeng Liu , Zheng Jiang , Pinan Zhu , Hanyu Liu , Chao Li

Deep learning has significantly advanced image analysis across diverse domains but often depends on large, annotated datasets for success. Transfer learning addresses this challenge by utilizing pre-trained models to tackle new tasks with…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Ana Davila , Jacinto Colan , Yasuhisa Hasegawa

Spatial transcriptomics is an emerging field that enables the identification of functional regions based on the spatial distribution of gene expression. Integrating this functional information present in transcriptomic data with structural…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Shanaka Liyanaarachchi , Chathurya Wijethunga , Shihab Aaqil Ahamed , Akthas Absar , Ranga Rodrigo

Spatial transcriptomics enables spatial gene expression profiling, motivating computational models that capture spatially conditioned regulatory relationships. We introduce SAGE-FM, a lightweight spatial transcriptomics foundation model…

Machine Learning · Computer Science 2026-01-23 Xianghao Zhan , Jingyu Xu , Yuanning Zheng , Zinaida Good , Olivier Gevaert

Time series, spatial data, and images are natural applications of Neural Processes. However, when such data exhibit strong periodicity and quasi-periodicity, existing methods often suffer from underfitting and generalise poorly beyond the…

Machine Learning · Computer Science 2026-05-12 Xianhe Chen , Hao Chen , Yingzhen Li

The rapid development of spatial transcriptomics(ST) enables the measurement of gene expression at spatial resolution, making it possible to simultaneously profile the gene expression, spatial locations of spots, and the matched…

Artificial Intelligence · Computer Science 2024-06-19 Changxi Chi , Hang Shi , Qi Zhu , Daoqiang Zhang , Wei Shao

Precision matrix estimation is essential in various fields; yet it is challenging when samples for the target study are limited. Transfer learning can enhance estimation accuracy by leveraging data from related source studies. We propose…

Machine Learning · Statistics 2026-03-31 Boxin Zhao , Cong Ma , Mladen Kolar

Recent work (Baluja, 2017) showed that using a pair of deep encoders and decoders, embedding a full-size secret image into a container image of the same size is achieved. This method distributes the information of the secret image across…

Cryptography and Security · Computer Science 2019-01-29 Parisa Babaheidarian , Mark Wallace

The paper presents a novel deep learning approach, which extracts latent information from trained Deep Neural Networks (DNNs) and derives concise representations that are analyzed in an effective, unified way for prediction purposes. It is…

Machine Learning · Computer Science 2020-09-22 D. Kollias , N. Bouas , Y. Vlaxos , V. Brillakis , M. Seferis , I. Kollia , L. Sukissian , J. Wingate , S. Kollias

Spatial transcriptomics methods capture cellular measurements such as gene expression and cell types at specific locations in a cell, helping provide a localized picture of tissue health. Traditional visualization techniques superimpose the…

Quantitative Methods · Quantitative Biology 2024-10-16 Siyuan Zhao , G. Elisabeta Marai