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Spatial transcriptomics has revolutionized tissue analysis by simultaneously mapping gene expression, spatial topography, and histological context across consecutive tissue sections, enabling systematic investigation of spatial…

Applications · Statistics 2025-10-24 Meng Zhou , Shuangge Ma , Mengyun Wu

Vision-and-language pretraining (VLP) in the medical field utilizes contrastive learning on image-text pairs to achieve effective transfer across tasks. Yet, current VLP approaches with the masked modeling strategy face two challenges when…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Biao Wu , Yutong Xie , Zeyu Zhang , Minh Hieu Phan , Qi Chen , Ling Chen , Qi Wu

Medical imaging diagnosis increasingly relies on Machine Learning (ML) models. This is a task that is often hampered by severely imbalanced datasets, where positive cases can be quite rare. Their use is further compromised by their limited…

Machine Learning · Computer Science 2024-01-26 Yumnah Hasan , Allan de Lima , Fatemeh Amerehi , Darian Reyes Fernandez de Bulnes , Patrick Healy , Conor Ryan

Chromosome recognition is an essential task in karyotyping, which plays a vital role in birth defect diagnosis and biomedical research. However, existing classification methods face significant challenges due to the inter-class similarity…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ruijia Chang , Suncheng Xiang , Chengyu Zhou , Kui Su , Dahong Qian , Jun Wang

Computer Vision has proven to be a powerful tool for analyzing Spatial Transcriptomics (ST) data. However, current models that predict spatially resolved gene expression from histopathology images suffer from significant limitations due to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Paula Cárdenas , Leonardo Manrique , Daniela Vega , Daniela Ruiz , Pablo Arbeláez

Although efficient extraction of discriminative spatial-spectral features is critical for hyperspectral images classification (HSIC), it is difficult to achieve these features due to factors such as the spatial-spectral heterogeneity and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Yimin Zhu , Linlin Xu

Multimodal contrastive learning is a methodology for linking different data modalities; the canonical example is linking image and text data. The methodology is typically framed as the identification of a set of encoders, one for each…

Machine Learning · Statistics 2025-06-02 Ricardo Baptista , Andrew M. Stuart , Son Tran

Spatio-temporal prediction is crucial in numerous real-world applications, including traffic forecasting and crime prediction, which aim to improve public transportation and safety management. Many state-of-the-art models demonstrate the…

Machine Learning · Computer Science 2023-10-30 Jiabin Tang , Lianghao Xia , Jie Hu , Chao Huang

Multimodal change detection (MMCD) identifies changed areas in multimodal remote sensing (RS) data, demonstrating significant application value in land use monitoring, disaster assessment, and urban sustainable development. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Xuanguang Liu , Lei Ding , Yujie Li , Chenguang Dai , Zhenchao Zhang , Mengmeng Li , Ziyi Yang , Yifan Sun , Yongqi Sun , Hanyun Wang

Medical datasets and especially biobanks, often contain extensive tabular data with rich clinical information in addition to images. In practice, clinicians typically have less data, both in terms of diversity and scale, but still wish to…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Paul Hager , Martin J. Menten , Daniel Rueckert

Recent advancements in spatial transcriptomics technologies allow researchers to simultaneously measure RNA expression levels for hundreds to thousands of genes while preserving spatial information within tissues, providing critical…

Methodology · Statistics 2025-07-31 Catherine Higgins , Jingyi Jessica Li , Michelle Carey

In a data-driven paradigm, machine learning (ML) is the central component for developing accurate and universal exchange-correlation (XC) functionals in density functional theory (DFT). It is well known that XC functionals must satisfy…

We propose SparseContrast, a new framework that merges dynamic sparse attention with contrastive learning for medical imaging, with a focus on chest X-ray disease detection in low-data settings. Traditional contrastive learning methods rely…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Paarth Prasad , Ruchika Malhotra

Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

Methodology · Statistics 2024-09-05 Qicheng Zhao , Qihuang Zhang

The integration of histology images and gene profiles has shown great promise for improving survival prediction in cancer. However, current approaches often struggle to model intra- and inter-modal interactions efficiently and effectively…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Yilan Zhang , Li Nanbo , Changchun Yang , Jürgen Schmidhuber , Xin Gao

This paper studies the task of inpainting man-made scenes. It is very challenging due to the difficulty in preserving the visual patterns of images, such as edges, lines, and junctions. Especially, most previous works are failed to restore…

Computer Vision and Pattern Recognition · Computer Science 2021-10-07 Chenjie Cao , Yanwei Fu

Molecular phenotyping is central in cancer precision medicine, but remains costly and standard methods only provide a tumour average profile. Microscopic morphological patterns observable in histopathology sections from tumours are…

Image and Video Processing · Electrical Eng. & Systems 2020-09-21 Yinxi Wang , Kimmo Kartasalo , Masi Valkonen , Christer Larsson , Pekka Ruusuvuori , Johan Hartman , Mattias Rantalainen

Molecular subtyping of breast cancer is crucial for personalized treatment and prognosis. Traditional classification approaches rely on either histopathological images or gene expression profiling, limiting their predictive power. In this…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Amin Honarmandi Shandiz

Self-supervised learning (SSL) has emerged as a powerful paradigm for Chest X-ray (CXR) analysis under limited annotations. Yet, existing SSL strategies remain suboptimal for medical imaging. Masked image modeling allocates substantial…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Wangyu Feng , Shawn Young , Lijian Xu

Medical image segmentation is a critical yet challenging task, primarily due to the difficulty of obtaining extensive datasets of high-quality, expert-annotated images. Contrastive learning presents a potential but still problematic…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shuang Zeng , Lei Zhu , Xinliang Zhang , Hangzhou He , Yanye Lu