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Linear models are widely used in computational neuroimaging to identify biomarkers associated with brain pathologies. However, interpreting the learned weights remains challenging, as they do not always yield clinically meaningful insights.…

Machine Learning · Computer Science 2026-04-23 Sara Petiton , Antoine Grigis , Raphaël Vock , Edouard Duchesnay

In daily life, we encounter diverse external stimuli, such as images, sounds, and videos. As research in multimodal stimuli and neuroscience advances, fMRI-based brain decoding has become a key tool for understanding brain perception and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Pengyu Liu , Guohua Dong , Dan Guo , Kun Li , Fengling Li , Xun Yang , Meng Wang , Xiaomin Ying

Neural encoding models aim to predict fMRI-measured brain responses to natural images. fMRI data is acquired as a 3D volume of voxels, where each voxel has a defined spatial location in the brain. However, conventional encoding models often…

Neurons and Cognition · Quantitative Biology 2026-02-11 Haomiao Chen , Keith W Jamison , Mert R. Sabuncu , Amy Kuceyeski

Visual brain decoding aims to decode visual information from human brain activities. Despite the great progress, one critical limitation of current brain decoding research lies in the lack of generalization capability to unseen subjects.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Xiangtao Kong , Kexin Huang , Ping Li , Lei Zhang

Addressing the question of visualising human mind could help us to find regions that are associated with observed cognition and responsible for expressing the elusive mental image, leading to a better understanding of cognitive function.…

Neurons and Cognition · Quantitative Biology 2021-02-11 Pan Wang , Rui Zhou , Shuo Wang , Ling Li , Wenjia Bai , Jialu Fan , Chunlin Li , Peter Childs , Yike Guo

Brain decoding techniques are essential for understanding the neurocognitive system. Although numerous methods have been introduced in this field, accurately aligning complex external stimuli with brain activities remains a formidable…

Neurons and Cognition · Quantitative Biology 2024-07-16 Heng Huang , Lin Zhao , Zihao Wu , Xiaowei Yu , Jing Zhang , Xintao Hu , Dajiang Zhu , Tianming Liu

We propose a statistical learning model for classifying cognitive processes based on distributed patterns of neural activation in the brain, acquired via functional magnetic resonance imaging (fMRI). In the proposed learning method, local…

Artificial Intelligence · Computer Science 2014-03-07 Orhan Firat , Mete Ozay , Ilke Oztekin , Fatos T. Yarman Vural

Decoding brain states from functional magnetic resonance imaging (fMRI) data is vital for advancing neuroscience and clinical applications. While traditional machine learning and deep learning approaches have made strides in leveraging the…

Machine Learning · Computer Science 2025-12-10 Danial Jafarzadeh Jazi , Maryam Hajiesmaeili

We propose an end-to-end deep neural encoder-decoder model to encode and decode brain activity in response to naturalistic stimuli using functional magnetic resonance imaging (fMRI) data. Leveraging temporally correlated input from…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Florian David , Michael Chan , Elenor Morgenroth , Patrik Vuilleumier , Dimitri Van De Ville

Knowing how the Human brain is anatomically and functionally organized at the level of a group of healthy individuals or patients is the primary goal of neuroimaging research. Yet computing an average of brain imaging data defined over a…

Computer Vision and Pattern Recognition · Computer Science 2015-04-13 Alexandre Gramfort , Gabriel Peyré , Marco Cuturi

Objectives: Functional connectivity triggered by naturalistic stimulus (e.g., movies) and machine learning techniques provide a great insight in exploring the brain functions such as fluid intelligence. However, functional connectivity are…

Artificial Intelligence · Computer Science 2021-01-07 Xiaobo Liu , Su Yang

Brain decoding involves the determination of a subject's cognitive state or an associated stimulus from functional neuroimaging data measuring brain activity. In this setting the cognitive state is typically characterized by an element of a…

Machine Learning · Statistics 2015-04-14 Nicole Croteau , Farouk S. Nathoo , Jiguo Cao , Ryan Budney

Visual image reconstruction from functional Magnetic Resonance Imaging (fMRI) is a fundamental task in brain decoding, providing a crucial pathway for understanding human perceptual mechanisms and developing advanced brain-computer…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Yudan Ren , Pengcheng Shi , Zihan Ma , Xiaowei He , Xiao Li

The dispute of how the human brain represents conceptual knowledge has been argued in many scientific fields. Brain imaging studies have shown that the spatial patterns of neural activation in the brain are correlated with thinking about…

Neurons and Cognition · Quantitative Biology 2018-06-15 Subba Reddy Oota , Naresh Manwani , Bapi Raju S

Brain decoding aims to reconstruct original stimuli from fMRI signals, providing insights into interpreting mental content. Current approaches rely heavily on subject-specific models due to the complex brain processing mechanisms and the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Zicheng Wang , Zhen Zhao , Luping Zhou , Parashkev Nachev

Neuroimaging-based prediction methods for intelligence and cognitive abilities have seen a rapid development in literature. Among different neuroimaging modalities, prediction based on functional connectivity (FC) has shown great promise.…

Neurons and Cognition · Quantitative Biology 2023-07-20 Yang Li , Xin Ma , Raj Sunderraman , Shihao Ji , Suprateek Kundu

Deep learning is leading to major advances in the realm of brain decoding from functional Magnetic Resonance Imaging (fMRI). However, the large inter-subject variability in brain characteristics has limited most studies to train models on…

Machine Learning · Computer Science 2023-12-12 Alexis Thual , Yohann Benchetrit , Felix Geilert , Jérémy Rapin , Iurii Makarov , Hubert Banville , Jean-Rémi King

Accounting for inter-individual variability in brain function is key to precision medicine. Here, by considering functional inter-individual variability as meaningful data rather than noise, we introduce VarCoNet, an enhanced…

Neural and Evolutionary Computing · Computer Science 2025-10-06 Charalampos Lamprou , Aamna Alshehhi , Leontios J. Hadjileontiadis , Mohamed L. Seghier

Neuroimaging-driven prediction of brain age, defined as the predicted biological age of a subject using only brain imaging data, is an exciting avenue of research. In this work we seek to build models of brain age based on functional…

Functional magnetic resonance imaging (fMRI) enables non-invasive brain disorder classification by capturing blood-oxygen-level-dependent (BOLD) signals. However, most existing methods rely on functional connectivity (FC) via Pearson…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Guoqi Yu , Xiaowei Hu , Angelica I. Aviles-Rivero , Anqi Qiu , Shujun Wang