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Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Machine Learning · Computer Science 2025-01-03 Arseniy Shumilov , Yueting Zhu , Negin Ashrafi , Armin Abdollahi , Greg Placencia , Kamiar Alaei , Maryam Pishgar

The timeliness of detection of a sepsis event in progress is a crucial factor in the outcome for the patient. Machine learning models built from data in electronic health records can be used as an effective tool for improving this…

Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…

Machine Learning · Computer Science 2025-09-03 Hejiang Cai , Di Wu , Ji Xu , Xiang Liu , Yiziting Zhu , Xin Shu , Yujie Li , Bin Yi

Sepsis is a life-threatening infectious syndrome associated with high mortality in intensive care units (ICUs). Early and accurate sepsis prediction (SP) is critical for timely intervention, yet remains challenging due to subtle early…

Machine Learning · Computer Science 2025-10-22 Zexi Tan , Tao Xie , Binbin Sun , Xiang Zhang , Yiqun Zhang , Yiu-Ming Cheung

Sepsis is a life-threatening condition that requires rapid detection and treatment to prevent progression to severe sepsis, septic shock, or multi-organ failure. Despite advances in medical technology, it remains a major challenge for…

Machine Learning · Computer Science 2025-11-11 Atharva Thakur , Shruti Dhumal

Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…

Machine Learning · Computer Science 2026-01-01 Alireza Rafiei , Farshid Hajati , Alireza Rezaee , Amirhossien Panahi , Shahadat Uddin

Current machine learning models aiming to predict sepsis from Electronic Health Records (EHR) do not account for the heterogeneity of the condition, despite its emerging importance in prognosis and treatment. This work demonstrates the…

Quantitative Methods · Quantitative Biology 2020-11-24 Zina Ibrahim , Honghan Wu , Ahmed Hamoud , Lukas Stappen , Richard Dobson , Andrea Agarossi

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…

Machine Learning · Computer Science 2019-03-07 Avijit Mitra , Khalid Ashraf

This study proposes the use of Machine Learning models to predict the early onset of sepsis using deidentified clinical data from Montefiore Medical Center in Bronx, NY, USA. A supervised learning approach was adopted, wherein an XGBoost…

Ensembling neural networks is a long-standing technique for improving the generalization error of neural networks by combining networks with orthogonal properties via a committee decision. We show that this technique is an ideal fit for…

Machine Learning · Computer Science 2023-06-12 Shigehiko Schamoni , Michael Hagmann , Stefan Riezler

Sepsis is a life-threatening organ malfunction caused by the host's inability to fight infection, which can lead to death without proper and immediate treatment. Therefore, early diagnosis and medical treatment of sepsis in critically ill…

Machine Learning · Computer Science 2023-04-14 Kevin Ewig , Xiangwen Lin , Tucker Stewart , Katherine Stern , Grant O'Keefe , Ankur Teredesai , Juhua Hu

Heart disease is a serious global health issue that claims millions of lives every year. Early detection and precise prediction are critical to the prevention and successful treatment of heart related issues. A lot of research utilizes…

Machine Learning · Computer Science 2024-07-30 Rahul Karmakar , Udita Ghosh , Arpita Pal , Sattwiki Dey , Debraj Malik , Priyabrata Sain

Sepsis is a life-threatening condition with organ dysfunction and is a leading cause of death and critical illness worldwide. Even a few hours of delay in the treatment of sepsis results in increased mortality. Early detection of sepsis…

Sepsis is a major public health concern due to its high morbidity, mortality, and cost. Its clinical outcome can be substantially improved through early detection and timely intervention. By leveraging publicly available datasets, machine…

Machine Learning · Computer Science 2026-02-04 Yin Jin , Tucker R. Stewart , Deyi Zhou , Chhavi Gupta , Arjita Nema , Scott C. Brakenridge , Grant E. O'Keefe , Juhua Hu

Despite decades of clinical research, sepsis remains a global public health crisis with high mortality, and morbidity. Currently, when sepsis is detected and the underlying pathogen is identified, organ damage may have already progressed to…

Epilepsy is a prevalent neurological disorder characterized by recurrent and unpredictable seizures, necessitating accurate prediction for effective management and patient care. Application of machine learning (ML) on electroencephalogram…

Signal Processing · Electrical Eng. & Systems 2023-08-11 Md. Simul Hasan Talukder , Rejwan Bin Sulaiman

Sepsis is a life threatening medical condition that occurs when the body has an extreme response to infection, leading to widespread inflammation, organ failure, and potentially death. Because sepsis can worsen rapidly, early detection is…

Machine Learning · Computer Science 2025-05-07 Oyindolapo O. Komolafe , Zhimin Mei , David Morales Zarate , Gregory William Spangenberg

The proliferation of early diagnostic technologies, including self-monitoring systems and wearables, coupled with the application of these technologies on large segments of healthy populations may significantly aggravate the problem of…

Machine Learning · Computer Science 2021-07-23 Anna Fedyukova , Douglas Pires , Daniel Capurro

Sepsis is the leading cause of death in non-coronary intensive care units. Moreover, a delay of antibiotic treatment of patients with severe sepsis by only few hours is associated with increased mortality. This insight makes accurate models…

Quantitative Methods · Quantitative Biology 2019-09-26 Shigehiko Schamoni , Holger A. Lindner , Verena Schneider-Lindner , Manfred Thiel , Stefan Riezler

Although there has been significant research in boosting of weak learners, there has been little work in the field of boosting from strong learners. This latter paradigm is a form of weighted voting with learned weights. In this work, we…

Machine Learning · Computer Science 2020-12-22 Matthew A. Reyna , Gari D. Clifford
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