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High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Recent work has shown that label-efficient few-shot learning through self-supervision can achieve promising medical image segmentation results. However, few-shot segmentation models typically rely on prototype representations of the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Stine Hansen , Srishti Gautam , Robert Jenssen , Michael Kampffmeyer

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

The Segment Anything Model (SAM) has demonstrated impressive performance in zero-shot promptable segmentation on natural images. The recently released Segment Anything Model 2 (SAM 2) claims to outperform SAM on images and extends the…

Image and Video Processing · Electrical Eng. & Systems 2025-04-16 Sourya Sengupta , Satrajit Chakrabarty , Ravi Soni

The recent Segment Anything Model (SAM) has demonstrated remarkable zero-shot capability and flexible geometric prompting in general image segmentation. However, SAM often struggles when handling various unconventional images, such as…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Aoran Xiao , Weihao Xuan , Heli Qi , Yun Xing , Ruijie Ren , Xiaoqin Zhang , Ling Shao , Shijian Lu

Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Zhongxi Qiu , Yan Hu , Heng Li , Jiang Liu

Accurate organ segmentation is essential for clinical tasks such as radiotherapy planning and disease monitoring. Recent foundation models like MedSAM achieve strong results using point or bounding-box prompts but still require manual…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Wenjie Zhang , Liming Luo , Mengnan He , Jiarui Hai , Jiancheng Ye

The Segment Anything Model (SAM) can achieve satisfactory segmentation performance under high-quality box prompts. However, SAM's robustness is compromised by the decline in box quality, limiting its practicality in clinical reality. In…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Yuhao Huang , Xin Yang , Han Zhou , Yan Cao , Haoran Dou , Fajin Dong , Dong Ni

Medical image segmentation is essential for clinical diagnosis, surgical planning, and treatment monitoring. Traditional approaches typically strive to tackle all medical image segmentation scenarios via one-time learning. However, in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Zhaori Liu , Mengyang Li , Hu Han , Enli Zhang , Shiguang Shan , Zhiming Zhao

The Segment Anything Model (SAM) has recently emerged as a groundbreaking foundation model for prompt-driven image segmentation tasks. However, both the original SAM and its medical variants require slice-by-slice manual prompting of target…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yichi Zhang , Shiyao Hu , Sijie Ren , Chen Jiang , Yuan Cheng , Yuan Qi

We present a zero-shot segmentation approach for agricultural imagery that leverages Plantnet, a large-scale plant classification model, in conjunction with its DinoV2 backbone and the Segment Anything Model (SAM). Rather than collecting…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Simon Ravé , Jean-Christophe Lombardo , Pejman Rasti , Alexis Joly , David Rousseau

Segment Anything Model (SAM) demonstrates powerful zero-shot capabilities; however, its accuracy and robustness significantly decrease when applied to medical image segmentation. Existing methods address this issue through modality fusion,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yiheng Zhong , Zihong Luo , Chengzhi Liu , Feilong Tang , Zelin Peng , Ming Hu , Yingzhen Hu , Jionglong Su , Zongyuan Ge , Imran Razzak

We introduce SAM3D, a new approach to semi-automatic zero-shot segmentation of 3D images building on the existing Segment Anything Model. We achieve fast and accurate segmentations in 3D images with a four-step strategy involving: user…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Trevor J. Chan , Aarush Sahni , Yijin Fang , Jie Li , Alisha Luthra , Alison Pouch , Chamith S. Rajapakse

Segment Anything Model (SAM) has emerged as a transformative approach in image segmentation, acclaimed for its robust zero-shot segmentation capabilities and flexible prompting system. Nonetheless, its performance is challenged by images…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Wei-Ting Chen , Yu-Jiet Vong , Sy-Yen Kuo , Sizhuo Ma , Jian Wang

Segmentation quality assessment (SQA) plays a critical role in the deployment of a medical image based AI system. Users need to be informed/alerted whenever an AI system generates unreliable/incorrect predictions. With the introduction of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Yizhe Zhang , Shuo Wang , Tao Zhou , Qi Dou , Danny Z. Chen

Image segmentation is a long-standing challenge in computer vision, studied continuously over several decades, as evidenced by seminal algorithms such as N-Cut, FCN, and MaskFormer. With the advent of foundation models (FMs), contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Tianfei Zhou , Wang Xia , Fei Zhang , Boyu Chang , Wenguan Wang , Ye Yuan , Ender Konukoglu , Daniel Cremers

We introduce the Segment Anything (SA) project: a new task, model, and dataset for image segmentation. Using our efficient model in a data collection loop, we built the largest segmentation dataset to date (by far), with over 1 billion…

Computer Vision and Pattern Recognition · Computer Science 2023-04-06 Alexander Kirillov , Eric Mintun , Nikhila Ravi , Hanzi Mao , Chloe Rolland , Laura Gustafson , Tete Xiao , Spencer Whitehead , Alexander C. Berg , Wan-Yen Lo , Piotr Dollár , Ross Girshick

Few-shot segmentation is the problem of learning to identify specific types of objects (e.g., airplanes) in images from a small set of labeled reference images. The current state of the art is driven by resource-intensive construction of…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Savinay Nagendra , Kashif Rashid , Chaopeng Shen , Daniel Kifer

The Segment Anything Model (SAM) is a recently proposed prompt-based segmentation model in a generic zero-shot segmentation approach. With the zero-shot segmentation capacity, SAM achieved impressive flexibility and precision on various…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Can Cui , Ruining Deng , Quan Liu , Tianyuan Yao , Shunxing Bao , Lucas W. Remedios , Yucheng Tang , Yuankai Huo

Segment Anything Model (SAM) has achieved impressive results for natural image segmentation with input prompts such as points and bounding boxes. Its success largely owes to massive labeled training data. However, directly applying SAM to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Jin Ye , Junlong Cheng , Jianpin Chen , Zhongying Deng , Tianbin Li , Haoyu Wang , Yanzhou Su , Ziyan Huang , Jilong Chen , Lei Jiang , Hui Sun , Min Zhu , Shaoting Zhang , Junjun He , Yu Qiao