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Deep learning models trained in a supervised setting have revolutionized audio and speech processing. However, their performance inherently depends on the quantity of human-annotated data, making them costly to scale and prone to poor…

Audio and Speech Processing · Electrical Eng. & Systems 2026-02-12 Theo Lepage , Reda Dehak

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

Quantitative Methods · Quantitative Biology 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Self-supervised learning (SSL) for clinical time series data has received significant attention in recent literature, since these data are highly rich and provide important information about a patient's physiological state. However, most…

Machine Learning · Computer Science 2023-07-21 Aniruddh Raghu , Payal Chandak , Ridwan Alam , John Guttag , Collin M. Stultz

Alzheimer's Disease (AD), as the most devastating neurodegenerative disease worldwide, has reached nearly 10 million new cases annually. Current technology provides unprecedented opportunities to study the progression and etiology of this…

Neurons and Cognition · Quantitative Biology 2022-11-14 Zibin Zhao

Alzheimer's disease (AD) is an irreversible brain disease that can dramatically reduce quality of life, most commonly manifesting in older adults and eventually leading to the need for full-time care. Early detection is fundamental to…

Computation and Language · Computer Science 2019-06-14 Flavio Di Palo , Natalie Parde

Self-supervised learning (SSL) has recently achieved promising performance for 3D medical image analysis tasks. Most current methods follow existing SSL paradigm originally designed for photographic or natural images, which cannot…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Yankai Jiang , Mingze Sun , Heng Guo , Xiaoyu Bai , Ke Yan , Le Lu , Minfeng Xu

Electroencephalography (EEG) plays a crucial role in brain-computer interfaces (BCIs) and neurological diagnostics, but its real-world deployment faces challenges due to noise artifacts, missing data, and high annotation costs. We introduce…

Signal Processing · Electrical Eng. & Systems 2025-10-24 Meghna Roy Chowdhury , Yi Ding , Shreyas Sen

Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…

Image and Video Processing · Electrical Eng. & Systems 2021-01-07 Kuo Yang , Emad A. Mohammed

Reliable early detection of Alzheimer's disease (AD) is challenging, particularly due to limited availability of labeled data. While large language models (LLMs) have shown strong transfer capabilities across domains, adapting them to the…

Computation and Language · Computer Science 2026-02-13 Lei Jiang , Yue Zhou , Natalie Parde

Self-supervised learning (SSL) is an emerging technique that has been successfully employed to train convolutional neural networks (CNNs) and graph neural networks (GNNs) for more transferable, generalizable, and robust representation…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Prarthana Bhattacharyya , Chengjie Huang , Krzysztof Czarnecki

Existing research has shown the potential of classifying Alzheimers Disease (AD) from eye-tracking (ET) data with classifiers that rely on task-specific engineered features. In this paper, we investigate whether we can improve on existing…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Harshinee Sriram , Cristina Conati , Thalia Field

A major limitation in applying deep learning to artificial intelligence (AI) systems is the scarcity of high-quality curated datasets. We investigate strong augmentation based self-supervised learning (SSL) techniques to address this…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 John D. Miller , Vignesh A. Arasu , Albert X. Pu , Laurie R. Margolies , Weiva Sieh , Li Shen

Self-supervised learning (SSL) based speech foundation models have been applied to a wide range of ASR tasks. However, their application to dysarthric and elderly speech via data-intensive parameter fine-tuning is confronted by in-domain…

Audio and Speech Processing · Electrical Eng. & Systems 2024-07-22 Shujie Hu , Xurong Xie , Mengzhe Geng , Zengrui Jin , Jiajun Deng , Guinan Li , Yi Wang , Mingyu Cui , Tianzi Wang , Helen Meng , Xunying Liu

Depression, a prevalent mental health disorder impacting millions globally, demands reliable assessment systems. Unlike previous studies that focus solely on either detecting depression or predicting its severity, our work identifies…

Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are…

Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…

The past few years have witnessed a remarkable advance in deep learning for EEG-based sleep stage classification (SSC). However, the success of these models is attributed to possessing a massive amount of labeled data for training, limiting…

Signal Processing · Electrical Eng. & Systems 2022-10-14 Emadeldeen Eldele , Mohamed Ragab , Zhenghua Chen , Min Wu , Chee-Keong Kwoh , Xiaoli Li

Deep supervised learning algorithms typically require a large volume of labeled data to achieve satisfactory performance. However, the process of collecting and labeling such data can be expensive and time-consuming. Self-supervised…

Machine Learning · Computer Science 2024-07-16 Jie Gui , Tuo Chen , Jing Zhang , Qiong Cao , Zhenan Sun , Hao Luo , Dacheng Tao

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

The rapid global aging trend has led to an increase in dementia cases, including Alzheimer's disease, underscoring the urgent need for early and accurate diagnostic methods. Traditional diagnostic techniques, such as cognitive tests,…

Machine Learning · Computer Science 2024-09-06 Juan A. Berrios Moya