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We investigate Turing instability and pattern formation in two-dimensional domains for two reaction-diffusion models, obtained as diffusive limits of kinetic equations for mixtures of monatomic and polyatomic gases. The first model is of…

Mathematical Physics · Physics 2026-02-23 Stefano Boccelli , Giorgio Martalò , Romina Travaglini

We introduce a spatially extended mathematical model for Duchenne muscular dystrophy based on a damage-driven paradigm, in which immune recruitment is triggered by tissue injury. The model is formulated as a reaction--diffusion--chemotaxis…

Mathematical Physics · Physics 2026-04-06 Gaetana Gambino , Francesco Gargano , Alessandra Rizzo , Vincenzo Sciacca

We consider a reaction-diffusion process with retardation. The particles, immersed in traps initially, remain inactive until another particle is annihilated spontaneously with a rate $\lambda$ at a certain point $\vec x$. In that case the…

Statistical Mechanics · Physics 2015-06-25 Michael Schulz , Steffen Trimper , Knud Zabrocki

We explore a mechanism of pattern formation arising in processes described by a system of a single reaction-diffusion equation coupled with ordinary differential equations. Such systems of equations arise from the modeling of interactions…

Analysis of PDEs · Mathematics 2020-07-15 Steffen Härting , Anna Marciniak-Czochra

Reaction--diffusion mechanism are a robust paradigm that can be used to represent many biological and physical phenomena over multiple spatial scales. Applications include intracellular dynamics, the migration of cells and the patterns…

Quantitative Methods · Quantitative Biology 2021-01-01 Cameron A. Smith , Christian A. Yates

We consider a multi-species reaction-diffusion system that arises in epidemiology to describe the spread of several strains, or variants, of a disease in a population. Our model is a natural spatial, multi-species, extension of the…

Analysis of PDEs · Mathematics 2022-08-02 Romain Ducasse , Samuel Nordmann

This paper aims to investigate a reaction-diffusion model which describes in-host infection for Mycobacterium tuberculosis (Mtb) allowing random motion (i.e. linear diffusion) and chemotaxis (i.e. non-linear diffusion) of macrophages and…

Populations and Evolution · Quantitative Biology 2024-10-16 C. Accarino , R. Accarino , F. Capone , R. De Luca , L. Fiorentino , G. Massa

Reaction-diffusion systems have been proposed as a model for pattern formation and morphogenesis. The Fickian diffusion typically employed in these constructions model the Brownian motion of particles. The biological and chemical elements…

Quantitative Methods · Quantitative Biology 2023-11-09 Siddhartha Srivastava , Krishna Garikipati

We study systems of reaction-diffusion equations with discontinuous spatially distributed hysteresis in the right-hand side. The input of hysteresis is given by a vector-valued function of space and time. Such systems describe hysteretic…

Analysis of PDEs · Mathematics 2013-09-27 Pavel Gurevich , Sergey Tikhomirov

A key problem in modelling the evolution dynamics of infectious diseases is the mathematical representation of the mechanism of transmission of the contagion. Models with a finite number of subpopulations can be described via systems of…

Optimization and Control · Mathematics 2017-03-09 Sebastian Anita , Vincenzo Capasso

Reaction-diffusion systems where transition rates exhibit quenched disorder are common in physical and chemical systems. We study pair reactions on a periodic two-dimensional lattice, including continuous deposition and spontaneous…

Disordered Systems and Neural Networks · Physics 2010-11-10 A. Wolff , I. Lohmar , J. Krug , Y. Frank , O. Biham

Many mathematical models for biological phenomena, such as the spread of diseases, are based on reaction-diffusion equations for densities of interacting cell populations. We present a consistent derivation of reaction-diffusion equations…

Analysis of PDEs · Mathematics 2026-02-23 Marzia Bisi , Davide Cusseddu , Ana Jacinta Soares , Romina Travaglini

We propose a mathematical kinetic framework to investigate interactions between tumor cells and the immune system, focusing on the spatial dynamics of tumor progression and immune responses. We develop two kinetic models: one describes a…

Cell Behavior · Quantitative Biology 2026-02-24 Martina Conte , Romina Travaglini

Mathematical and computational modelling in oncology has played an increasingly important role in not only understanding the impact of various approaches to treatment on tumour growth, but in optimizing dosing regimens and aiding the…

Tissues and Organs · Quantitative Biology 2025-07-03 Molly Brennan , Andrew L. Krause , Edgardo Villar-Sepúlveda , Christopher B. Prior

We investigated existence of global weak solutions for a system of chemotaxis type with nonlinear degenerate diffusion, arising in modelling Multiple Sclerosis disease. The model consists of three equations describing the evolution of…

Analysis of PDEs · Mathematics 2024-05-10 S. Fagioli , E. Radici , L. Romagnoli

Signaling molecules play an important role for many cellular functions. We investigate here a general system of two membrane reaction-diffusion equations coupled to a diffusion equation inside the cell by a Robin-type boundary condition and…

Analysis of PDEs · Mathematics 2015-06-16 Andreas Rätz , Matthias Röger

Mathematical modeling is now used commonly in the analysis of signaling networks. With advances in high resolution microscopy, the spatial location of different signaling molecules and the spatio-temporal dynamics of signaling microdomains…

Subcellular Processes · Quantitative Biology 2016-07-26 Jasmine Nirody , Padmini Rangamani

Currently, free flaps and pedicled flaps are assessed for reperfusion in post-operative care using colour, capillary refill, temperature, texture and Doppler signal (if available). While these techniques are effective, they are prone to…

Medical Physics · Physics 2022-04-18 Mark Main , Richard JJ Pilkington , Graham M Gibson , Akhil Kallepalli

In this paper we study a nonlinear reaction-diffusion system which models an infectious disease caused by bacteria such as those for cholera. One of the significant features in this model is that a certain portion of the recovered human…

Analysis of PDEs · Mathematics 2022-02-01 Hong-Ming Yin , Jun Zou

The Turing instability paradigm is revisited in the context of a multispecies diffusion scheme derived from a self-consistent microscopic formulation. The analysis is developed with reference to the case of two species. These latter share…

Biological Physics · Physics 2012-07-02 Duccio Fanelli , Claudia Cianci , Francesca Di Patti