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This work explores a novel data augmentation method based on Large Language Models (LLMs) for predicting item difficulty and response time of retired USMLE Multiple-Choice Questions (MCQs) in the BEA 2024 Shared Task. Our approach is based…

Computation and Language · Computer Science 2024-04-23 Ana-Cristina Rogoz , Radu Tudor Ionescu

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of…

Computation and Language · Computer Science 2024-03-29 Shan Chen , Yingya Li , Sheng Lu , Hoang Van , Hugo JWL Aerts , Guergana K. Savova , Danielle S. Bitterman

As large language models (LLMs) grow in parameter size and capabilities, such as interaction through prompting, they open up new ways of interfacing with automatic speech recognition (ASR) systems beyond rescoring n-best lists. This work…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-25 Maryam Naderi , Enno Hermann , Alexandre Nanchen , Sevada Hovsepyan , Mathew Magimai. -Doss

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

Computation and Language · Computer Science 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

This paper explores the application of prompt engineering to enhance the performance of large language models (LLMs) in the domain of Traditional Chinese Medicine (TCM). We propose TCM-Prompt, a framework that integrates various pre-trained…

Computation and Language · Computer Science 2024-10-28 Yirui Chen , Qinyu Xiao , Jia Yi , Jing Chen , Mengyang Wang

Large Language Models (LLMs) have shown impressive capabilities in many scenarios, but their performance depends, in part, on the choice of prompt. Past research has focused on optimizing prompts specific to a task. However, much less…

Computation and Language · Computer Science 2026-04-07 Lechen Zhang , Tolga Ergen , Lajanugen Logeswaran , Moontae Lee , David Jurgens

This study investigated the application of Large Language Models (LLMs) for simplifying biomedical texts to enhance health literacy. Using a public dataset, which included plain language adaptations of biomedical abstracts, we developed and…

Computation and Language · Computer Science 2025-12-19 Primoz Kocbek , Leon Kopitar , Gregor Stiglic

Large Language Models (LLMs) generate responses to questions; however, their effectiveness is often hindered by sub-optimal quality of answers and occasional failures to provide accurate responses to questions. To address these challenges,…

Computation and Language · Computer Science 2024-02-06 Liang Zhang , Katherine Jijo , Spurthi Setty , Eden Chung , Fatima Javid , Natan Vidra , Tommy Clifford

Large Language Models (LLMs) can be tasked with scoring texts according to pre-defined criteria and on a defined scale, but there is no recognised optimal prompting strategy for this. This article focuses on the task of LLMs scoring journal…

Digital Libraries · Computer Science 2025-12-02 Mike Thelwall

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

We explore the potential of Large Language Models (LLMs) to assist and potentially correct physicians in medical decision-making tasks. We evaluate several LLMs, including Meditron, Llama2, and Mistral, to analyze the ability of these…

Computation and Language · Computer Science 2024-05-07 Burcu Sayin , Pasquale Minervini , Jacopo Staiano , Andrea Passerini

Pre-trained LLMs have demonstrated substantial capabilities across a range of conventional natural language processing (NLP) tasks, such as summarization and entity recognition. In this paper, we explore the application of LLMs in the…

Quantitative Methods · Quantitative Biology 2024-08-14 Kamyar Zeinalipour , Neda Jamshidi , Monica Bianchini , Marco Maggini , Marco Gori

The rapid identification of medical emergencies through digital communication channels remains a critical challenge in modern healthcare delivery, particularly with the increasing prevalence of telemedicine. This paper presents a novel…

Machine Learning · Computer Science 2024-12-24 Ferit Akaybicen , Aaron Cummings , Lota Iwuagwu , Xinyue Zhang , Modupe Adewuyi

In the face of rapidly expanding online medical literature, automated systems for aggregating and summarizing information are becoming increasingly crucial for healthcare professionals and patients. Large Language Models (LLMs), with their…

Computation and Language · Computer Science 2024-03-07 Niraj Yagnik , Jay Jhaveri , Vivek Sharma , Gabriel Pila

Predicting enzymatic reactions is crucial for applications in biocatalysis, metabolic engineering, and drug discovery, yet it remains a complex and resource-intensive task. Large Language Models (LLMs) have recently demonstrated remarkable…

Artificial Intelligence · Computer Science 2025-05-12 Lorenzo Di Fruscia , Jana Marie Weber

Large language models (LLMs) have demonstrated significant advancements in error handling. Current error-handling works are performed in a passive manner, with explicit error-handling instructions. However, in real-world scenarios, explicit…

Computation and Language · Computer Science 2025-06-03 Jiayi Zeng , Yizhe Feng , Mengliang He , Wenhui Lei , Wei Zhang , Zeming Liu , Xiaoming Shi , Aimin Zhou

This study presents a novel two-stage Retrieve-Rank system for automated ICD-10-CM medical coding, comparing its performance against a Vanilla Large Language Model (LLM) approach. Evaluating both systems on a dataset of 100 single-term…

Information Retrieval · Computer Science 2024-07-19 Keith Kwan