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Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these…

Planning effective interventions in biological systems requires treatment-effect models that adapt to unseen biological contexts by identifying their specific underlying mechanisms. Yet single-cell perturbation datasets span only a handful…

Machine Learning · Computer Science 2026-05-08 Marvin Sextro , Weronika Kłos , Gabriel Dernbach

Large Language Models (LLMs) generate realistic synthetic data but offer no guarantee that their outputs respect the causal mechanisms governing the target domain. We introduce CausalSynth, a framework that decouples causal structure…

Machine Learning · Computer Science 2026-05-19 Zehua Cheng , Wei Dai , Jiahao Sun , Thomas Lukasiewicz

Discovering and exploiting the causal structure in the environment is a crucial challenge for intelligent agents. Here we explore whether causal reasoning can emerge via meta-reinforcement learning. We train a recurrent network with…

Causal knowledge is vital for effective reasoning in science, as causal relations, unlike correlations, allow one to reason about the outcomes of interventions. Algorithms that can discover causal relations from observational data are based…

Machine Learning · Statistics 2019-11-12 Anish Dhir , Ciarán M. Lee

Causal deep learning (CDL) is a new and important research area in the larger field of machine learning. With CDL, researchers aim to structure and encode causal knowledge in the extremely flexible representation space of deep learning…

Machine Learning · Computer Science 2022-12-05 Jeroen Berrevoets , Krzysztof Kacprzyk , Zhaozhi Qian , Mihaela van der Schaar

Inferring causal relationships from observational data is rarely straightforward, but the problem is especially difficult in high dimensions. For these applications, causal discovery algorithms typically require parametric restrictions or…

Methodology · Statistics 2022-06-29 David S. Watson , Ricardo Silva

Most of previous machine learning algorithms are proposed based on the i.i.d. hypothesis. However, this ideal assumption is often violated in real applications, where selection bias may arise between training and testing process. Moreover,…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Zheyan Shen , Peng Cui , Kun Kuang , Bo Li , Peixuan Chen

Ensuring safe operation of safety-critical complex systems interacting with their environment poses significant challenges, particularly when the system's world model relies on machine learning algorithms to process the perception input. A…

Robotics · Computer Science 2025-05-27 Roman Gansch , Lina Putze , Tjark Koopmann , Jan Reich , Christian Neurohr

Causal discovery aims to uncover cause-and-effect relationships encoded in causal graphs by leveraging observational, interventional data, or their combination. The majority of existing causal discovery methods are developed assuming…

Machine Learning · Computer Science 2024-06-25 Muhammad Qasim Elahi , Lai Wei , Murat Kocaoglu , Mahsa Ghasemi

Deep neural networks have significantly improved the performance of low-level vision tasks but also increased the difficulty of interpretability. A deep understanding of deep models is beneficial for both network design and practical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Jinfan Hu , Jinjin Gu , Shiyao Yu , Fanghua Yu , Zheyuan Li , Zhiyuan You , Chaochao Lu , Chao Dong

Causal discovery can be a powerful tool for investigating causality when a system can be observed but is inaccessible to experiments in practice. Despite this, it is rarely used in any scientific or medical fields. One of the major hurdles…

Machine Learning · Statistics 2019-10-07 Erich Kummerfeld , Alexander Rix

Conversational semantic role labeling (CSRL) is believed to be a crucial step towards dialogue understanding. However, it remains a major challenge for existing CSRL parser to handle conversational structural information. In this paper, we…

Computation and Language · Computer Science 2021-11-05 Han Wu , Kun Xu , Linqi Song

We present two online causal structure learning algorithms which can track changes in a causal structure and process data in a dynamic real-time manner. Standard causal structure learning algorithms assume that causal structure does not…

Artificial Intelligence · Computer Science 2019-07-16 Durdane Kocacoban , James Cussens

Supervised causal learning has shown promise in causal discovery, yet it often struggles with generalization across diverse interventional settings, particularly when intervention targets are unknown. To address this, we propose TICL…

Machine Learning · Computer Science 2026-02-24 Wei Chen , Rui Ding , Bojun Huang , Yang Zhang , Qiang Fu , Yuxuan Liang , Han Shi , Dongmei Zhang

Estimation of causal effects is critical to a range of scientific disciplines. Existing methods for this task either require interventional data, knowledge about the ground truth causal graph, or rely on assumptions such as…

Machine Learning · Computer Science 2025-11-21 Jake Robertson , Arik Reuter , Siyuan Guo , Noah Hollmann , Frank Hutter , Bernhard Schölkopf

Advances in single-cell omics allow for unprecedented insights into the transcription profiles of individual cells. When combined with large-scale perturbation screens, through which specific biological mechanisms can be targeted, these…

Machine Learning · Computer Science 2023-10-24 Alejandro Tejada-Lapuerta , Paul Bertin , Stefan Bauer , Hananeh Aliee , Yoshua Bengio , Fabian J. Theis

In this work, we propose a novel algorithmic framework for data sharing and coordinated exploration for the purpose of learning more data-efficient and better performing policies under a concurrent reinforcement learning (CRL) setting. In…

Machine Learning · Statistics 2024-02-01 Tim Tse , Isaac Chan , Zhitang Chen

Causal representation learning promises to extend causal models to hidden causal variables from raw entangled measurements. However, most progress has focused on proving identifiability results in different settings, and we are not aware of…

Machine Learning · Computer Science 2025-02-04 Dingling Yao , Caroline Muller , Francesco Locatello

This paper studies the problem of learning causal structures from observational data. We reformulate the Structural Equation Model (SEM) with additive noises in a form parameterized by binary graph adjacency matrix and show that, if the…

Machine Learning · Computer Science 2022-01-11 Ignavier Ng , Shengyu Zhu , Zhuangyan Fang , Haoyang Li , Zhitang Chen , Jun Wang