Related papers: Normative brain mapping of 3-dimensional morphomet…
Although normal homologous brain structures are approximately symmetrical by definition, they also have shape differences due to e.g. natural ageing. On the other hand, neurodegenerative conditions induce their own changes in this…
Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…
We propose two methodologies in order to better understand the inter-individual variability of resting-state functional Magnetic Resonance Imaging (fMRI) brain data. The aim of the study was to quantify whether the average dendrogram is…
Nervous systems are characterized by neurons displaying a diversity of morphological shapes. Traditionally, different shapes have been qualitatively described based on visual inspection and quantitatively described based on morphometric…
Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are…
Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions using big volumes of neuroimaging data. Functional magnetic resonance imaging (fMRI) can produce these…
In this paper, we studied the association between the change of structural brain volumes to the potential development of Alzheimer's disease (AD). Using a simple abstraction technique, we converted regional cortical and subcortical volume…
Resting state functional magnetic resonance images (fMRI) are commonly used for classification of patients as having Alzheimer's disease (AD), mild cognitive impairment (MCI), or being cognitive normal (CN). Most methods use time-series…
Brain network analysis provides an interpretable framework for characterizing brain organization and has been widely used for neurological disorder identification. Recent advances in self-supervised learning have motivated the development…
Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…
Designing generative models for 3D structural brain MRI that synthesize morphologically-plausible and attribute-specific (e.g., age, sex, disease state) samples is an active area of research. Existing approaches based on frameworks like…
Neuroimaging data, particularly from techniques like MRI or PET, offer rich but complex information about brain structure and activity. To manage this complexity, latent representation models - such as Autoencoders, Generative Adversarial…
We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of…
Brain aging, and more specifically the difference between the chronological and the biological age of a person, may be a promising biomarker for identifying neurodegenerative diseases. For this purpose accurate prediction is important but…
Statistical shape modeling (SSM) directly from 3D medical images is an underutilized tool for detecting pathology, diagnosing disease, and conducting population-level morphology analysis. Deep learning frameworks have increased the…
This study presents an innovative method for Alzheimer's disease diagnosis using 3D MRI designed to enhance the explainability of model decisions. Our approach adopts a soft attention mechanism, enabling 2D CNNs to extract volumetric…
Functional Magnetic Resonance Imaging (fMRI) relies on multi-step data processing pipelines to accurately determine brain activity; among them, the crucial step of spatial smoothing. These pipelines are commonly suboptimal, given the local…
Real-world settings often do not allow acquisition of high-resolution volumetric images for accurate morphological assessment and diagnostic. In clinical practice it is frequently common to acquire only sparse data (e.g. individual slices)…
High-dimensional neuroimaging data presents challenges for assessing neurodegenerative diseases due to complex non-linear relationships. Variational Autoencoders (VAEs) can encode scans into lower-dimensional latent spaces capturing…
Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…