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The advancement of single-cell RNA-sequencing (scRNA-seq) technologies allow us to study the individual level cell-type-specific gene expression networks by direct inference of genes' conditional independence structures. scRNA-seq data…

Methodology · Statistics 2024-09-20 Changhao Ge , Hongzhe Li

Symbolic regression with polynomial neural networks and polynomial neural ordinary differential equations (ODEs) are two recent and powerful approaches for equation recovery of many science and engineering problems. However, these methods…

Machine Learning · Computer Science 2023-08-28 Colby Fronk , Jaewoong Yun , Prashant Singh , Linda Petzold

We present a novel Bayesian approach for high-dimensional grouped regression under sparsity. We leverage a sparse projection method that uses a sparsity-inducing map to derive an induced posterior on a lower-dimensional parameter space. Our…

Methodology · Statistics 2026-05-25 Samhita Pal , Subhashis Ghosal

Reconstruction of gene regulatory networks is the process of identifying gene dependency from gene expression profile through some computation techniques. In our human body, though all cells pose similar genetic material but the activation…

We propose a new framework, called Poisson learning, for graph based semi-supervised learning at very low label rates. Poisson learning is motivated by the need to address the degeneracy of Laplacian semi-supervised learning in this regime.…

Machine Learning · Computer Science 2020-08-17 Jeff Calder , Brendan Cook , Matthew Thorpe , Dejan Slepcev

We propose a new image denoising algorithm when the data is contaminated by a Poisson noise. As in the Non-Local Means filter, the proposed algorithm is based on a weighted linear combination of the bserved image. But in contract to the…

Applications · Statistics 2012-01-31 Qiyu Jin , Ion Grama , Quansheng Liu

Architecture, size, and shape of glands are most important patterns used by pathologists for assessment of cancer malignancy in prostate histopathological tissue slides. Varying structures of glands along with cumbersome manual observations…

Image and Video Processing · Electrical Eng. & Systems 2019-10-10 Malay Singh , Emarene Mationg Kalaw , Wang Jie , Mundher Al-Shabi , Chin Fong Wong , Danilo Medina Giron , Kian-Tai Chong , Maxine Tan , Zeng Zeng , Hwee Kuan Lee

Prostate cancer (PCa) was the most frequently diagnosed cancer among American men in 2023. The histological grading of biopsies is essential for diagnosis, and various deep learning-based solutions have been developed to assist with this…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Ekaterina Redekop , Mara Pleasure , Zichen Wang , Anthony Sisk , Yang Zong , Kimberly Flores , William Speier , Corey W. Arnold

The robust Poisson method is becoming increasingly popular when estimating the association of exposures with a binary outcome. Unlike the logistic regression model, the robust Poisson method yields results that can be interpreted as risk or…

Methodology · Statistics 2022-09-14 Denis Talbot , Miceline Mésidor , Yohann Chiu , Marc Simard , Caroline Sirois

Many high-energy physics analyses require the presence of leptons from $W$, $Z$, or $H$ boson decay. For these analyses, signatures that mimic such leptons present a `fake lepton' background that must be estimated. Since the magnitude of…

High Energy Physics - Experiment · Physics 2016-06-23 Erich W. Varnes

Correctly assessing the malignancy of breast lesions identified during ultrasound examinations is crucial for effective clinical decision-making. However, the current "golden standard" relies on manual BI-RADS scoring by clinicians, often…

Machine Learning · Computer Science 2024-08-29 Alek Fröhlich , Thiago Ramos , Gustavo Cabello , Isabela Buzatto , Rafael Izbicki , Daniel Tiezzi

Patient-reported outcomes (PROs) directly collected from cancer patients being treated with radiation therapy play a vital role in assisting clinicians in counseling patients regarding likely toxicities. Precise prediction and evaluation of…

Machine Learning · Computer Science 2024-11-19 Yang Yan , Zhong Chen , Cai Xu , Xinglei Shen , Jay Shiao , John Einck , Ronald C Chen , Hao Gao

Neural Processes (NPs; Garnelo et al., 2018a,b) are a rich class of models for meta-learning that map data sets directly to predictive stochastic processes. We provide a rigorous analysis of the standard maximum-likelihood objective used to…

Machine Learning · Statistics 2021-01-12 Wessel P. Bruinsma , James Requeima , Andrew Y. K. Foong , Jonathan Gordon , Richard E. Turner

We treat an image restoration problem with a Poisson noise chan- nel using a Bayesian framework. The Poisson randomness might be appeared in observation of low contrast object in the field of imaging. The noise observation is often hard to…

Computer Vision and Pattern Recognition · Computer Science 2014-12-09 Hayaru Shouno

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

The PC algorithm uses conditional independence tests for model selection in graphical modeling with acyclic directed graphs. In Gaussian models, tests of conditional independence are typically based on Pearson correlations, and…

Statistics Theory · Mathematics 2012-07-03 Naftali Harris , Mathias Drton

The progression of lung cancer implies the intrinsic ordinal relationship of lung nodules at different stages-from benign to unsure then to malignant. This problem can be solved by ordinal regression methods, which is between classification…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Yiming Lei , Hongming Shan , Junping Zhang

Medical images can be used to predict a clinical score coding for the severity of a disease, a pain level or the complexity of a cognitive task. In all these cases, the predicted variable has a natural order. While a standard classifier…

Machine Learning · Computer Science 2012-10-02 Fabian Pedregosa , Alexandre Gramfort , Gaël Varoquaux , Elodie Cauvet , Christophe Pallier , Bertrand Thirion

We propose an anomaly detection technique for high-resolution X-ray spectroscopy. The method is based on the neural network architecture variational autoencoder, and requires only {\it normal} samples for training. We implement the network…

Instrumentation and Methods for Astrophysics · Physics 2019-06-12 Y. Ichinohe , S. Yamada

We introduce a scalable Bayesian preference learning method for identifying convincing arguments in the absence of gold-standard rat- ings or rankings. In contrast to previous work, we avoid the need for separate methods to perform quality…

Computation and Language · Computer Science 2018-06-08 Edwin Simpson , Iryna Gurevych
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