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If Uncertainty Quantification (UQ) is crucial to achieve trustworthy Machine Learning (ML), most UQ methods suffer from disparate and inconsistent evaluation protocols. We claim this inconsistency results from the unclear requirements the…

Machine Learning · Computer Science 2022-07-28 Victor Bouvier , Simona Maggio , Alexandre Abraham , Léo Dreyfus-Schmidt

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

This paper focuses on the uncertainty estimation for white matter lesions (WML) segmentation in magnetic resonance imaging (MRI). On one side, voxel-scale segmentation errors cause the erroneous delineation of the lesions; on the other…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Nataliia Molchanova , Vatsal Raina , Andrey Malinin , Francesco La Rosa , Henning Muller , Mark Gales , Cristina Granziera , Mara Graziani , Meritxell Bach Cuadra

Uncertainty estimation is important for interpreting the trustworthiness of machine learning models in many applications. This is especially critical in the data-driven active learning setting where the goal is to achieve a certain accuracy…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Bo Li , Tommy Sonne Alstrøm

Effective Uncertainty Quantification (UQ) represents a key aspect for reliable deployment of Large Language Models (LLMs) in automated decision-making and beyond. Yet, for LLM generation with multiple choice structure, the state-of-the-art…

Machine Learning · Computer Science 2025-11-18 Ramzi Dakhmouche , Adrien Letellier , Hossein Gorji

Uncertainty quantification (UQ) has emerged as a promising approach for detecting hallucinations and low-quality output of Large Language Models (LLMs). However, obtaining proper uncertainty scores is complicated by the conditional…

The ability to replicate predictions by machine learning (ML) or artificial intelligence (AI) models and results in scientific workflows that incorporate such ML/AI predictions is driven by numerous factors. An uncertainty-aware metric that…

Machine Learning · Computer Science 2023-08-28 Line Pouchard , Kristofer G. Reyes , Francis J. Alexander , Byung-Jun Yoon

Epistemic uncertainty quantification (UQ) identifies where models lack knowledge. Traditional UQ methods, often based on Bayesian neural networks, are not suitable for pre-trained non-Bayesian models. Our study addresses quantifying…

Machine Learning · Computer Science 2024-04-17 Hanjing Wang , Qiang Ji

Uncertainty quantification (UQ) is important for reliability assessment and enhancement of machine learning models. In deep learning, uncertainties arise not only from data, but also from the training procedure that often injects…

Machine Learning · Statistics 2023-11-13 Ziyi Huang , Henry Lam , Haofeng Zhang

Uncertainty quantification (UQ) is essential for assessing the reliability of Earth observation (EO) products. However, the extensive use of machine learning models in EO introduces an additional layer of complexity, as those models…

Machine Learning · Computer Science 2024-12-10 Yuanyuan Wang , Qian Song , Dawood Wasif , Muhammad Shahzad , Christoph Koller , Jonathan Bamber , Xiao Xiang Zhu

Uncertainty quantification (UQ) is a critical aspect of artificial intelligence (AI) systems, particularly in high-risk domains such as healthcare, autonomous systems, and financial technology, where decision-making processes must account…

Uncertainty quantification (UQ) is the process of systematically determining and characterizing the degree of confidence in computational model predictions. In the context of systems biology, especially with dynamic models, UQ is crucial…

Machine Learning · Statistics 2024-10-29 Alberto Portela , Julio R. Banga , Marcos Matabuena

Deep learning has played a major role in the interpretation of dermoscopic images for detecting skin defects and abnormalities. However, current deep learning solutions for dermatological lesion analysis are typically limited in providing…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Gun-Hee Lee , Han-Bin Ko , Seong-Whan Lee

Quantifying uncertainties for machine learning models is a critical step to reduce human verification effort by detecting predictions with low confidence. This paper proposes a method for uncertainty quantification (UQ) of table structure…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Kehinde Ajayi , Leizhen Zhang , Yi He , Jian Wu

Deep learning based methods for automatic organ segmentation have shown promise in aiding diagnosis and treatment planning. However, quantifying and understanding the uncertainty associated with model predictions is crucial in critical…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Jadie Adams , Shireen Y. Elhabian

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Deep learning has been shown to be highly effective for automatic modulation classification (AMC), which is a pivotal technology for next-generation cognitive communications. Yet, existing deep learning methods for AMC often lack robust…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Huian Yang , Rajeev Sahay

Uncertainty in medical image segmentation tasks, especially inter-rater variability, arising from differences in interpretations and annotations by various experts, presents a significant challenge in achieving consistent and reliable image…

Uncertainty Quantification (UQ) is a promising approach to improve model reliability, yet quantifying the uncertainty of Large Language Models (LLMs) is non-trivial. In this work, we establish a connection between the uncertainty of LLMs…

Computation and Language · Computer Science 2025-10-16 Mingda Li , Xinyu Li , Weinan Zhang , Longxuan Ma

Deep learning (DL) models have provided state-of-the-art performance in various medical imaging benchmarking challenges, including the Brain Tumor Segmentation (BraTS) challenges. However, the task of focal pathology multi-compartment…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Raghav Mehta , Angelos Filos , Ujjwal Baid , Chiharu Sako , Richard McKinley , Michael Rebsamen , Katrin Datwyler , Raphael Meier , Piotr Radojewski , Gowtham Krishnan Murugesan , Sahil Nalawade , Chandan Ganesh , Ben Wagner , Fang F. Yu , Baowei Fei , Ananth J. Madhuranthakam , Joseph A. Maldjian , Laura Daza , Catalina Gomez , Pablo Arbelaez , Chengliang Dai , Shuo Wang , Hadrien Reynaud , Yuan-han Mo , Elsa Angelini , Yike Guo , Wenjia Bai , Subhashis Banerjee , Lin-min Pei , Murat AK , Sarahi Rosas-Gonzalez , Ilyess Zemmoura , Clovis Tauber , Minh H. Vu , Tufve Nyholm , Tommy Lofstedt , Laura Mora Ballestar , Veronica Vilaplana , Hugh McHugh , Gonzalo Maso Talou , Alan Wang , Jay Patel , Ken Chang , Katharina Hoebel , Mishka Gidwani , Nishanth Arun , Sharut Gupta , Mehak Aggarwal , Praveer Singh , Elizabeth R. Gerstner , Jayashree Kalpathy-Cramer , Nicolas Boutry , Alexis Huard , Lasitha Vidyaratne , Md Monibor Rahman , Khan M. Iftekharuddin , Joseph Chazalon , Elodie Puybareau , Guillaume Tochon , Jun Ma , Mariano Cabezas , Xavier Llado , Arnau Oliver , Liliana Valencia , Sergi Valverde , Mehdi Amian , Mohammadreza Soltaninejad , Andriy Myronenko , Ali Hatamizadeh , Xue Feng , Quan Dou , Nicholas Tustison , Craig Meyer , Nisarg A. Shah , Sanjay Talbar , Marc-Andre Weber , Abhishek Mahajan , Andras Jakab , Roland Wiest , Hassan M. Fathallah-Shaykh , Arash Nazeri , Mikhail Milchenko1 , Daniel Marcus , Aikaterini Kotrotsou , Rivka Colen , John Freymann , Justin Kirby , Christos Davatzikos , Bjoern Menze , Spyridon Bakas , Yarin Gal , Tal Arbel