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The classical approach to diffusion processes is based on Fick's law that the flux is proportional to the concentration gradient. Various phenomena occurring during propagation of penetrating liquids in polymers show that this type of…

Analysis of PDEs · Mathematics 2010-12-10 Dmitry A. Vorotnikov

The main objective of this paper is analysis of the initial-boundary value problems for the linear and semilinear time-fractional diffusion equations with a uniformly elliptic spatial differential operator of the second order and the Caputo…

Analysis of PDEs · Mathematics 2022-08-10 Yuri Luchko , Masahiro Yamamoto

We study the asymptotic behaviour of a system of nonlinear reaction--diffusion--advection equations in a domain consisting of two bulk regions connected via microscopic channels distributed within a thin membrane. Both the width of the…

Analysis of PDEs · Mathematics 2025-12-15 Lucas M. Fix , Gianna Götzmann , Malte A. Peter , Jan-F. Pietschmann

Diffusion-mediated surface phenomena are crucial for human life and industry, with examples ranging from oxygen capture by lung alveolar surface to heterogeneous catalysis, gene regulation, membrane permeation and filtration processes.…

Statistical Mechanics · Physics 2020-08-19 Denis S. Grebenkov

Restrictions to molecular motion by barriers (membranes) are ubiquitous in biological tissues, porous media and composite materials. A major challenge is to characterize the microstructure of a material or an organism nondestructively using…

Soft Condensed Matter · Physics 2011-03-11 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

Recent advancements in the ability to construct three-dimensional (3D) tissues and organoids from stem cells and biomaterials have not only opened abundant new research avenues in disease modeling and regenerative medicine but also have…

Tissues and Organs · Quantitative Biology 2017-07-27 Richard J. McMurtrey

Cell polarity and movement are fundamental to many biological functions. Experimental and theoretically studies have indicated that interactions of certain proteins lead to the cell polarization which plays a key role in controlling the…

Dynamical Systems · Mathematics 2022-08-12 Shuang Liu , Li-Tien Cheng , Bo Li

We study the mass-conserved reaction-diffusion system known as the wave-pinning model, which serves as a minimal framework for describing cell polarity. In this model, the interplay between reaction kinetics and slow diffusion forms a sharp…

Dynamical Systems · Mathematics 2026-01-09 Shunsuke Kobayashi , Koya Sakakibara , Taikei Uechi

In living cells, proteins combine 3D bulk diffusion and 1D sliding along the DNA to reach a target faster. This process is known as facilitated diffusion, and we investigate its dynamics in the physiologically relevant case of confined DNA.…

Soft Condensed Matter · Physics 2015-06-12 G. Foffano , D. Marenduzzo , E. Orlandini

Let $\Omega$ be a domain in $\mathbb R^N$, where $N \ge 2$ and $\partial\Omega$ is not necessarily bounded. We consider nonlinear diffusion equations of the form $\partial_t u= \Delta \phi(u)$. Let $u=u(x,t)$ be the solution of either the…

Analysis of PDEs · Mathematics 2011-08-10 Rolando Magnanini , Shigeru Sakaguchi

We investigate reversible diffusion-influenced reactions of an isolated pair in two dimensions. To this end, we employ convolution relations that permit deriving the survival probability of the reversible reaction directly in terms of the…

Quantitative Methods · Quantitative Biology 2015-06-16 Thorsten Prüstel , M. Tachiya

A Dirichlet problem is considered for the eikonal equation in an anisotropic medium. The nonlinear boundary value problem (BVP) formulated in the present work is the limit of the diffusion-reaction problem with a reaction parameter tending…

Numerical Analysis · Computer Science 2018-02-20 Alexander G. Churbanov , Petr N. Vabishchevich

We study small perturbations of diffusion processes in $\mathbb{R}^d$ that leave invariant a finite collection of hypersurfaces. Each surface is assumed to be repelling for the unperturbed process, and the unperturbed motion on each of the…

Probability · Mathematics 2026-02-12 Leonid Koralov , Chenglin Liu

In this paper we present a mathematical study of particle diffusion inside and outside a spherical biological cell that has been exposed on one side to a propagating planar diffusive front. The media inside and outside the spherical cell…

Biological Physics · Physics 2024-06-11 Sandeep Santhosh Kumar , Stanley J. Miklavcic

We investigate singularly perturbed elliptic problems with multiplicative nonlocal diffusion terms subject to Robin boundary conditions. The diffusion depends on a global quantity of the solution, which introduces a nonlocal coupling…

Analysis of PDEs · Mathematics 2026-04-08 Chiun-Chang Lee , Sang-Hyuck Moon , Wen Yang

We consider a domain $\Omega\subseteq\mathbb{R\!}^{\,2}$ with branched fractal boundary $\Gamma^{\infty}$ and parameter $\tau\in[1/2,\tau^{\ast}]$ introduced by Achdou and Tchou \cite{ACH08}, for $\tau^{\ast}\simeq 0.593465$, which acts as…

Analysis of PDEs · Mathematics 2025-07-25 Kevin Silva-Pérez , Alejandro Vélez-Santiago

The analytical solution of the equation describing diffusion of intrinsic point defects has been obtained for a one-dimensional finite-length domain. This solution is intended for investigating and modeling the changes in defect…

Materials Science · Physics 2014-06-26 O. I. Velichko

We propose a boundary element method for the accurate solution of the cell-by-cell bidomain model of electrophysiology. The cell-by-cell model, also called Extracellular-Membrane-Intracellular (EMI) model, is a system of reaction-diffusion…

Numerical Analysis · Mathematics 2024-06-28 Giacomo Rosilho de Souza , Rolf Krause , Simone Pezzuto

We consider a system of particles undergoing correlated diffusion with elastic boundary conditions on the half-line. By taking the large particle limit we establish existence and uniqueness for the limiting empirical measure valued process…

Probability · Mathematics 2022-10-19 Ben Hambly , Julian Meier , Andreas Sojmark

Recently, the problem of boundary stabilization for unstable linear constant-coefficient reaction-diffusion equation on N-balls has been solved by means of the backstepping method. However, the extension of this result to spatially-varying…

Optimization and Control · Mathematics 2016-01-11 Rafael Vazquez , Miroslav Krstic
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