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We consider the subdiffusion--absorption process in a system which consists of two different media separated by a thin membrane. The process is described by subdiffusion--absorption equations with fractional Riemann--Liouville time…

Statistical Mechanics · Physics 2018-08-01 Tadeusz Kosztołowicz

In this paper we study subdiffusion in a system with a thin membrane. At the beginning, the random walk of a particle is considered in a system with a discrete time and space variable and then the probability describing the evolution of the…

Statistical Mechanics · Physics 2015-05-21 Tadeusz Kosztołowicz

We present a new method for modeling tissue perfusion on the capillary scale. The microvasculature is represented by a network of one-dimensional vessel segments embedded in the extra-vascular space. Vascular and extra-vascular space…

Computational Physics · Physics 2020-03-23 Timo Koch , Martin Schneider , Rainer Helmig , Patrick Jenny

Morphological change of bilayer membrane in vivo is not a spontaneous procedure but modulated by various types of proteins in general. Most of these modulations are associated with the localization of related proteins in the crowded lipid…

Quantitative Methods · Quantitative Biology 2016-06-30 Michael Mikucki , Y. C. Zhou

Realistic examples of reaction-diffusion phenomena governing spatial and spatiotemporal pattern formation are rarely isolated systems, either chemically or thermodynamically. However, even formulations of `open' reaction-diffusion systems…

Pattern Formation and Solitons · Physics 2021-05-14 Andrew L. Krause , Václav Klika , Philip K. Maini , Denis Headon , Eamonn A. Gaffney

Motivated by models of signaling pathways in B lymphocytes, which have extremely large nuclei, we study the question of how reaction-diffusion equations in thin $2D$ domains may be approximated by diffusion equations in regions of smaller…

Analysis of PDEs · Mathematics 2020-07-17 Adam Bobrowski

We consider a continuum mechanical model for the migration of multiple cell populations through parts of tissue separated by thin membranes. In this model, cells belonging to different populations may be characterised by different…

Analysis of PDEs · Mathematics 2021-09-28 Chiara Giverso , Tommaso Lorenzi , Luigi Preziosi

We consider the diffusion-advection problem in two simple cellular flow models (often invoked as examples for subdiffusive tracer's motion) and concentrate on the intermediate time range, in which the tracer's motion indeed may show…

Fluid Dynamics · Physics 2016-09-28 Patrick Pöschke , Igor M. Sokolov , Alexander A. Nepomnyashchy , Michael A. Zaks

The aim of this paper is to discuss the appropriate modelling of in- and outflow boundary conditions for nonlinear drift-diffusion models for the transport of particles including size exclusion and their effect on the behaviour of…

Analysis of PDEs · Mathematics 2016-11-03 Martin Burger , Jan-Frederik Pietschmann

We consider a model system consisting of two reaction-diffusion equations, where one species diffuses in a volume while the other species diffuses on the surface which surrounds the volume. The two equations are coupled via a nonlinear…

Analysis of PDEs · Mathematics 2017-07-21 Tang Quoc Bao , Klemens Fellner , Evangelos Latos

The random motion of a Brownian particle confined in some finite domain is considered. Quite generally, the relevant statistical properties involve infinite series, whose coefficients are related to the eigenvalues of the diffusion…

Statistical Mechanics · Physics 2010-04-26 Thomas Bickel

This paper presents an extended version of the article [Franz, S., Kopteva, N.: J. Differential Equations, 252 (2012)]. The main improvement compared to the latter is in that here we additionally estimate the mixed second-order derivative…

Analysis of PDEs · Mathematics 2022-12-23 Sebastian Franz , Natalia Kopteva

This paper develops an approach for solving perpetual discounted optimal stopping problems for multidimensional diffusions, with special emphasis on the $d$-dimensional Wiener process. We first obtain some verification theorems for…

Probability · Mathematics 2016-11-04 Sören Christensen , Fabián Crocce , Ernesto Mordecki , Paavo Salminen

For characterizing the Brownian motion in a bounded domain: $\Omega$, it is well-known that the boundary conditions of the classical diffusion equation just rely on the given information of the solution along the boundary of a domain; on…

Analysis of PDEs · Mathematics 2018-01-24 Weihua Deng , Buyang Li , Wenyi Tian , Pingwen Zhang

In this paper the numerical solution of potential problems defined on 3D unbounded domains is addressed with Boundary Element Methods (BEMs), since in this way the problem is studied only on the boundary, and thus any finite approximation…

Numerical Analysis · Mathematics 2022-05-06 Antonella Falini , Carlotta Giannelli , Tadej Kanduc , Maria Lucia Sampoli , Alessandra Sestini

We propose certain approach of solving two-dimensional non-stationary and stationary advection-diffusion-reaction boundary value problems through their reduction to the set of corresponding one-dimensional problems. This method leverages…

Numerical Analysis · Mathematics 2024-11-19 R. Drebotiy , H. Shynkarenko

In cell membranes, proteins and lipids diffuse in a highly crowded and heterogeneous landscape, where aggregates and dense domains of proteins or lipids obstruct the path of diffusing molecules. In general, hindered motion gives rise to…

Soft Condensed Matter · Physics 2010-06-16 Margaret R. Horton , Felix Höfling , Joachim O. Rädler , Thomas Franosch

Using techniques of the theory of semigroups of linear operators we study the question of approximating solutions to equations governing diffusion in thin layers separated by a semi-permeable membrane. We show that as thickness of the…

Analysis of PDEs · Mathematics 2019-08-08 Adam Bobrowski

We study a weighted eigenvalue problem with anisotropic diffusion in bounded Lipschitz domains $\Omega\subset \mathbb{R}^{N} $, $N\ge1$, under Robin boundary conditions, proving the existence of two positive eigenvalues $\lambda^{\pm}$…

Analysis of PDEs · Mathematics 2023-03-03 Benedetta Pellacci , Giovanni Pisante , Delia Schiera

We consider singularly perturbed convection-diffusion equations on one-dimensional networks (metric graphs) as well as the transport problems arising in the vanishing diffusion limit. Suitable coupling condition at inner vertices are…

Analysis of PDEs · Mathematics 2020-04-22 Herbert Egger , Nora Philippi