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While RNA technologies hold immense therapeutic potential in a range of applications from vaccination to gene editing, the broad implementation of these technologies is hindered by the challenge of delivering these agents effectively. Lipid…

Biomolecules · Quantitative Biology 2023-08-30 Daisy Yi Ding , Yuhui Zhang , Yuan Jia , Jiuzhi Sun

The discovery of new ionizable lipids for efficient lipid nanoparticle (LNP)-mediated RNA delivery remains a critical bottleneck for RNA-based therapeutics development. Recent advances have highlighted the potential of machine learning (ML)…

Network traffic classification is a crucial research area aiming to enhance service quality, streamline network management, and bolster cybersecurity. To address the growing complexity of transmission encryption techniques, various machine…

Machine Learning · Computer Science 2024-10-22 Tongze Wang , Xiaohui Xie , Wenduo Wang , Chuyi Wang , Youjian Zhao , Yong Cui

U-shaped architectures have long dominated the field of medical image segmentation, while Transformers are widely employed for modeling long-range dependencies. The former typically handles scale variations implicitly by aggregating…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yanhua Zhang , Ke Zhang , Jingyu Wang , Gabriella Balestra , Samanta Rosati , Yulin Wu , Wuwei Wang , Valentina Giannini

Transformer-based architectures have become the backbone of both uni-modal and multi-modal foundation models, largely due to their scalability via attention mechanisms, resulting in a rich ecosystem of publicly available pre-trained models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Xiuwei Chen , Wentao Hu , Xiao Dong , Sihao Lin , Zisheng Chen , Meng Cao , Yina Zhuang , Jianhua Han , Hang Xu , Xiaodan Liang

Previous research on lightweight models has primarily focused on CNNs and Transformer-based designs. CNNs, with their local receptive fields, struggle to capture long-range dependencies, while Transformers, despite their global modeling…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Haoyang He , Jiangning Zhang , Yuxuan Cai , Hongxu Chen , Xiaobin Hu , Zhenye Gan , Yabiao Wang , Chengjie Wang , Yunsheng Wu , Lei Xie

Multimodal Large Language Models (MLLMs) have attracted much attention for their multifunctionality. However, traditional Transformer architectures incur significant overhead due to their secondary computational complexity. To address this…

Computer Vision and Pattern Recognition · Computer Science 2024-08-22 Wenjun Huang , Jiakai Pan , Jiahao Tang , Yanyu Ding , Yifei Xing , Yuhe Wang , Zhengzhuo Wang , Jianguo Hu

Multi-modality image fusion aims to integrate the merits of images from different sources and render high-quality fusion images. However, existing feature extraction and fusion methods are either constrained by inherent local reduction bias…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Chenguang Zhu , Shan Gao , Huafeng Chen , Guangqian Guo , Chaowei Wang , Yaoxing Wang , Chen Shu Lei , Quanjiang Fan

Linear RNN architectures, like Mamba, can be competitive with Transformer models in language modeling while having advantageous deployment characteristics. Given the focus on training large-scale Transformer models, we consider the…

Machine Learning · Computer Science 2025-06-30 Junxiong Wang , Daniele Paliotta , Avner May , Alexander M. Rush , Tri Dao

With the rapid growth of encrypted network traffic, effective traffic classification has become essential for network security and quality of service management. Current machine learning and deep learning approaches for traffic…

Machine Learning · Computer Science 2026-01-30 Tongze Wang , Xiaohui Xie , Wenduo Wang , Chuyi Wang , Jinzhou Liu , Boyan Huang , Yannan Hu , Youjian Zhao , Yong Cui

Accurate and efficient multivariate time series (MTS) analysis is increasingly critical for a wide range of intelligent applications. Within this realm, Transformers have emerged as the predominant architecture due to their strong ability…

Machine Learning · Computer Science 2026-05-19 Rui An , Haohao Qu , Wenqi Fan , Xuequn Shang , Qing Li

Accurate prediction of RNA-associated interactions is essential for understanding cellular regulation and advancing drug discovery. While Biological Large Language Models (BioLLMs) such as ESM-2 and RiNALMo provide powerful sequence…

Genomics · Quantitative Biology 2026-02-27 Rabeya Tus Sadia , Qiang Ye , Qiang Cheng

Recent advancements in medical imaging have resulted in more complex and diverse images, with challenges such as high anatomical variability, blurred tissue boundaries, low organ contrast, and noise. Traditional segmentation methods…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Yufeng Jiang , Zongxi Li , Xiangyan Chen , Haoran Xie , Jing Cai

The LiDAR 3D object detector that strikes a balance between accuracy and speed is crucial for achieving real-time perception in autonomous driving. However, many existing LiDAR detection models depend on complex feature transformations,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Rui Yu , Runkai Zhao , Jiagen Li , Qingsong Zhao , HuaiCheng Yan , Meng Wang

Remote sensing change detection (CD) has made significant advancements with the adoption of Convolutional Neural Networks (CNNs) and Transformers. While CNNs offer powerful feature extraction, they are constrained by receptive field…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 JunYao Kaung , HongWei Ge

Semantic segmentation of high-resolution remote sensing images is vital in downstream applications such as land-cover mapping, urban planning and disaster assessment.Existing Transformer-based methods suffer from the constraint between…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Enze Zhu , Zhan Chen , Dingkai Wang , Hanru Shi , Xiaoxuan Liu , Lei Wang

Multi-modal medical image synthesis involves nonlinear transformation of tissue signals between source and target modalities, where tissues exhibit contextual interactions across diverse spatial distances. As such, the utility of a network…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Omer F. Atli , Bilal Kabas , Fuat Arslan , Arda C. Demirtas , Mahmut Yurt , Onat Dalmaz , Tolga Çukur

Abnormality detection in medical imaging is a critical task requiring both high efficiency and accuracy to support effective diagnosis. While convolutional neural networks (CNNs) and Transformer-based models are widely used, both face…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Yao Wang , Dong Yang , Zhi Qiao , Wenjian Huang , Liuzhi Yang , Zhen Qian

Time series prediction, a crucial task across various domains, faces significant challenges due to the inherent complexities of time series data, including non-stationarity, multi-scale periodicity, and transient dynamics, particularly when…

Machine Learning · Computer Science 2025-07-18 Qianru Zhang , Chenglei Yu , Haixin Wang , Yudong Yan , Yuansheng Cao , Siu-Ming Yiu , Tailin Wu , Hongzhi Yin

Over the past decade, convolutional neural networks (CNN) have shown very competitive performance in medical image analysis tasks, such as disease classification, tumor segmentation, and lesion detection. CNN has great advantages in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Yin Dai , Yifan Gao
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