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Conversational agents are increasingly used to address emotional needs on top of information needs. One use case of increasing interest are counselling-style mental health and behaviour change interventions, with large language model…

Human-Computer Interaction · Computer Science 2026-04-22 Selina Meyer , David Elsweiler

We present Genie-CAT, a tool-augmented large-language-model (LLM) system designed to accelerate scientific hypothesis generation in protein design. Using metalloproteins (e.g., ferredoxins) as a case study, Genie-CAT integrates four…

Quantitative Methods · Quantitative Biology 2025-11-25 Bruno Jacob , Khushbu Agarwal , Marcel Baer , Peter Rice , Simone Raugei

The language generation and reasoning capabilities of large language models (LLMs) have enabled conversational systems with impressive performance in a variety of tasks, from code generation, to composing essays, to passing STEM and legal…

Artificial Intelligence · Computer Science 2025-02-28 Konstantina Christakopoulou , Iris Qu , John Canny , Andrew Goodridge , Cj Adams , Minmin Chen , Maja Matarić

Conversational Assistants (CA) are increasingly supporting human workers in knowledge management. Traditionally, CAs respond in specific ways to predefined user intents and conversation patterns. However, this rigidness does not handle the…

Human-Computer Interaction · Computer Science 2024-07-15 Samuel Kernan Freire , Chaofan Wang , Evangelos Niforatos

Task-oriented conversational systems are essential for efficiently addressing diverse user needs, yet their development requires substantial amounts of high-quality conversational data that is challenging and costly to obtain. While large…

Information Retrieval · Computer Science 2025-11-06 Zhefan Wang , Ning Geng , Zhiqiang Guo , Weizhi Ma , Min Zhang

Recent advances in Large Language Models (LLMs) have propelled conversational AI from traditional dialogue systems into sophisticated agents capable of autonomous actions, contextual awareness, and multi-turn interactions with users. Yet,…

Artificial Intelligence · Computer Science 2025-04-25 Emre Can Acikgoz , Cheng Qian , Hongru Wang , Vardhan Dongre , Xiusi Chen , Heng Ji , Dilek Hakkani-Tür , Gokhan Tur

Leveraging advanced reasoning capabilities and extensive world knowledge of large language models (LLMs) to construct generative agents for solving complex real-world problems is a major trend. However, LLMs inherently lack embodiment as…

Human-Computer Interaction · Computer Science 2024-07-23 Ye Jin , Ruoxuan Yang , Zhijie Yi , Xiaoxi Shen , Huiling Peng , Xiaoan Liu , Jingli Qin , Jiayang Li , Jintao Xie , Peizhong Gao , Guyue Zhou , Jiangtao Gong

Large language models (LLMs) have emerged as valuable tools for many natural language understanding tasks. In safety-critical applications such as healthcare, the utility of these models is governed by their ability to generate outputs that…

Computation and Language · Computer Science 2023-03-31 Varun Nair , Elliot Schumacher , Geoffrey Tso , Anitha Kannan

Large Language Models (LLMs) like GPT-4 have revolutionized natural language processing, showing remarkable linguistic proficiency and reasoning capabilities. However, their application in strategic multi-agent decision-making environments…

Computation and Language · Computer Science 2024-05-29 Chuanhao Li , Runhan Yang , Tiankai Li , Milad Bafarassat , Kourosh Sharifi , Dirk Bergemann , Zhuoran Yang

The reasoning capability of large language models (LLMs), defined as their ability to analyze, infer, and make decisions based on input information, is essential for building intelligent task-oriented dialogue systems. However, existing…

Computation and Language · Computer Science 2026-03-02 Yu Zhu , Kai Yang

Large Language Models~(LLMs) have demonstrated capabilities across various applications but face challenges such as hallucination, limited reasoning abilities, and factual inconsistencies, especially when tackling complex, domain-specific…

To understand diverse natural language commands, virtual assistants today are trained with numerous labor-intensive, manually annotated sentences. This paper presents a methodology and the Genie toolkit that can handle new compound commands…

Computation and Language · Computer Science 2019-04-22 Giovanni Campagna , Silei Xu , Mehrad Moradshahi , Richard Socher , Monica S. Lam

The latest advancements in AI and deep learning have led to a breakthrough in large language model (LLM)-based agents such as GPT-4. However, many commercial conversational agent development tools are pipeline-based and have limitations in…

Computation and Language · Computer Science 2023-09-08 Mina Foosherian , Hendrik Purwins , Purna Rathnayake , Touhidul Alam , Rui Teimao , Klaus-Dieter Thoben

The ability of large language models (LLMs) to mimic human-like intelligence has led to a surge in LLM-based autonomous agents. Though recent LLMs seem capable of planning and reasoning given user instructions, their effectiveness in…

Open-source pre-trained Large Language Models (LLMs) exhibit strong language understanding and generation capabilities, making them highly successful in a variety of tasks. However, when used as agents for dealing with complex problems in…

Computation and Language · Computer Science 2024-04-01 Qinhao Zhou , Zihan Zhang , Xiang Xiang , Ke Wang , Yuchuan Wu , Yongbin Li

Large language models (LLMs) are increasingly seen as assistants, copilots, and consultants, capable of supporting a wide range of tasks through natural conversation. However, most systems remain constrained by a linear request-response…

Computation and Language · Computer Science 2026-05-05 Jiaqi Chen , Yanzhe Zhang , Yutong Zhang , Yijia Shao , Diyi Yang

Large language models (LLMs) are powerful dialogue agents, but specializing them towards fulfilling a specific function can be challenging. Instructing tuning, i.e. tuning models on instruction and sample responses generated by humans…

Computation and Language · Computer Science 2024-01-11 Dennis Ulmer , Elman Mansimov , Kaixiang Lin , Justin Sun , Xibin Gao , Yi Zhang

Generating complex multi-turn goal-oriented dialogue agents is a difficult problem that has seen a considerable focus from many leaders in the tech industry, including IBM, Google, Amazon, and Microsoft. This is in large part due to the…

The rise of big data has amplified the need for efficient, user-friendly automated machine learning (AutoML) tools. However, the intricacy of understanding domain-specific data and defining prediction tasks necessitates human intervention…

Computation and Language · Computer Science 2023-05-24 Md Mahadi Hassan , Alex Knipper , Shubhra Kanti Karmaker Santu

Computational thinking, and by extension, computer programming, is notoriously challenging to learn. Conversational agents and generative artificial intelligence (genAI) have the potential to facilitate this learning process by offering…

Human-Computer Interaction · Computer Science 2024-06-17 Jacob Penney , João Felipe Pimentel , Igor Steinmacher , Marco A. Gerosa
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