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In this paper, we present a novel approach to approximate the gain function of the feedback particle filter (FPF). The exact gain function is the solution of a Poisson equation involving a probability-weighted Laplacian. The numerical…

Machine Learning · Computer Science 2022-06-07 S. Yagiz Olmez , Amirhossein Taghvaei , Prashant G. Mehta

In this article we provide homotopy solutions of a cancer nonlinear model describing the dynamics of tumor cells in interaction with healthy and effector immune cells. We apply a semi-analytic technique for solving strongly nonlinear…

We introduce the so called DeepParticle method to learn and generate invariant measures of stochastic dynamical systems with physical parameters based on data computed from an interacting particle method (IPM). We utilize the expressiveness…

Machine Learning · Computer Science 2022-06-22 Zhongjian Wang , Jack Xin , Zhiwen Zhang

This paper addresses 6-DOF (degree-of-freedom) tactile localization, i.e. the pose estimation of tridimensional objects given tactile measurements. This estimation problem is fundamental for the operation of autonomous robots that are often…

Robotics · Computer Science 2025-09-16 Giulia Vezzani , Ugo Pattacini , Giorgio Battistelli , Luigi Chisci , Lorenzo Natale

In the past few decades, the development of fluorescent technologies and microscopic techniques has greatly improved scientists' ability to observe real-time single-cell activities. In this paper, we consider the filtering problem associate…

Quantitative Methods · Quantitative Biology 2022-07-27 Zhou Fang , Ankit Gupta , Mustafa Khammash

An adpative integration technique for time advancement of particle motion in the context of coupled computational fluid dynamics (CFD) - discrete element method (DEM) simulations is presented in this work. CFD-DEM models provide an accurate…

Computational Physics · Physics 2018-02-28 Hariswaran Sitaraman , Ray Grout

Inferring spatial transcriptomics (ST) from histology enables scalable histogenomic profiling, yet current methods are largely restricted to single-tissue models. This fragmentation fails to leverage biological principles shared across…

Machine Learning · Computer Science 2026-05-13 Susu Hu , Stefanie Speidel

Interacting particle methods are increasingly used to sample from complex and high-dimensional distributions. These stochastic particle integration techniques can be interpreted as an universal acceptance-rejection sequential particle…

Computational Finance · Quantitative Finance 2012-10-30 P. Del Moral , G. W. Peters , Ch. Vergé

Objective: Tumor Treating Fields (TTFields) is an emerging approach for cancer therapy that inhibits tumor cell proliferation by applying alternating electric fields (EF) of intermediate frequency and low intensity. The TTFields-induced…

Medical Physics · Physics 2024-10-17 Minmin Wang , Xu Xie , Zhengbo Fan , Yue Lan , Yun Pan , Guangdi Chen , Shaomin Zhang , Yuxing Wang

Glioblastoma Multiforme is a malignant brain tumor with poor prognosis. There have been numerous attempts to model the invasion of tumorous glioma cells via partial differential equations in the form of advection-diffusion-reaction…

Cell Behavior · Quantitative Biology 2020-01-16 Christian Engwer , Michael Wenske

An efficient, iterative semi-implicit (SI) numerical method for the time integration of stiff wave systems is presented. Physics-based assumptions are used to derive a convergent iterative formulation of the SI scheme which enables the…

Computational Physics · Physics 2008-07-02 N. F. Loureiro , G. W. Hammett

Gradient flow in the 2-Wasserstein space is widely used to optimize functionals over probability distributions and is typically implemented using an interacting particle system with $n$ particles. Analyzing these algorithms requires showing…

Machine Learning · Computer Science 2026-03-27 Chandan Tankala , Dheeraj M. Nagaraj , Anant Raj

In industrial big data scenarios, high-dimensional sparse matrices (HDI) are widely used to characterize high-order interaction relationships among massive nodes. The stochastic gradient descent-based latent factor analysis (SGD-LFA) method…

Machine Learning · Computer Science 2025-08-26 Jinli Li , Shiyu Long , Minglian Han

This paper presents a two-phase method for learning interaction kernels of stochastic many-particle systems. After transforming stochastic trajectories of every particle into the particle density function by the kernel density estimation…

Computational Physics · Physics 2025-01-03 Yangxuan Shi , Wuyue Yang , Liu Hong

Tumour invasion is strongly influenced by microenvironment and, among other parameters, chemical stimuli play an important role. An innovative methodology for the quantitative investigation of chemotaxis in vitro by live imaging of…

Cell Behavior · Quantitative Biology 2022-03-29 Rosalia Ferraro , Flora Ascione , Prashant Dogra , Vittorio Cristini , Stefano Guido , Sergio Caserta

The filtering of a Markov diffusion process on a manifold from counting process observations leads to `large' changes in the conditional distribution upon an observed event, corresponding to a multiplication of the density by the intensity…

Optimization and Control · Mathematics 2019-11-01 Simone Carlo Surace , Anna Kutschireiter , Jean-Pascal Pfister

We formulate theoretical modeling approaches and develop practical computational simulation methods for investigating the non-equilibrium statistical mechanics of fluid interfaces with passive and active immersed particles. Our approaches…

Soft Condensed Matter · Physics 2024-10-03 Dev Jasuja , Paul J. Atzberger

The emergence of diffusion models has significantly advanced generative AI, improving the quality, realism, and creativity of image and video generation. Among them, Stable Diffusion (StableDiff) stands out as a key model for text-to-image…

Hardware Architecture · Computer Science 2025-07-03 Zhican Wang , Guanghui He , Hongxiang Fan

We propose a multiscale model of the invasion of the extracellular matrix by two types of cancer cells, the differentiated cancer cells and the cancer stem cells. We assume that the epithelial mesenchymal-like transition between them is…

Cell Behavior · Quantitative Biology 2016-04-19 Nikolaos Sfakianakis , Niklas Kolbe , Nadja Hellmann , Maria Lukacova-Medvidova

Artificial Intelligence (AI) based image analysis has an immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially…