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Manually tracing regions of interest (ROIs) within the liver is the de facto standard method for measuring liver attenuation on computed tomography (CT) in diagnosing nonalcoholic fatty liver disease (NAFLD). However, manual tracing is…
Objectives: To mathematically investigate urethral pressure and influencing parameters of stress urinary incontinence (SUI) in women, with focus on the clinical aspects of the mathematical modeling. Method: Several patients' data are…
Coronary heart disease (CHD) is the leading cause of adult death in the United States and worldwide, and for which the coronary angiography procedure is the primary gateway for diagnosis and clinical management decisions. The…
Atrial fibrillation (AF) is a cardiovascular disease identified as one of the main risk factors for stroke. The majority of strokes due to AF are caused by clots originating in the left atrial appendage (LAA). LAA occlusion is an effective…
Mechanical stresses in soft materials across different length scales play a fundamental role in understanding the function of biological systems and in the use of artificial materials for engineering soft machines and biomedical devices.…
Mean aortic pressure (MAP) is a major determinant of perfusion in all organs systems. The ability to forecast MAP would enhance the ability of physicians to estimate prognosis of the patient and assist in early detection of hemodynamic…
During episodes of atrial fibrillation, the heart's electrical activity becomes disorganized and shows fragmenting spiral waves. To systematically address how this pattern terminates using spatially extended simulations exceeds current…
The properties of intracranial aneurysms (IAs) walls are known to be driven by the underlying hemodynamics adjacent to the IA sac. Different pathways exist explaining the connections between hemodynamics and local tissue properties. The…
During intracranial aneurysm (IA) treatment with Diverters (FDs), the device/parent artery diameters ratio may influence the ability of the device to induce aneurysm healing response. Oversized FDs are safer to deploy but may not induce…
Surgical ablation (SA) is the most effective procedure to terminate atrial fibrillation (AF) in patients requiring concomitant open heart surgery. However, considering the great stress provoked in the patients heart, along with the benefits…
Recent data from the Federal Highway Administration highlights an alarming increase in fatalities and injuries in roadway work zones, emphasizing the need for enhanced worker safety measures. This study addresses this concern by evaluating…
Traumatic injuries are measured using the Abbreviated Injury Scale (AIS), which is a risk to life scale. New human computer models use stresses and strains to evaluate whether serious or fatal injuries are reached, unfortunately these…
The application of molecular dynamics (MD) simulations to quasistatic loading is severely limited by the large separation between atomic vibration timescales and experimentally relevant deformation rates. In this work we employ the…
Atrial fibrillation (AF) is the most common arrhythmia affecting millions of people in the Western countries and, due to the widespread impact on the population and its medical relevance, is largely investigated in both clinical and…
Accelerated life testing (ALT) is a method of reducing the lifetime of components through exposure to extreme stress. This method of obtaining lifetime information involves the design of a testing experiment, i.e., an accelerated test plan.…
The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…
This study evaluates two approaches applied to computed tomography (CT) images of patients with abdominal aortic aneurysm: one deterministic, based on tools of Approximation Theory, and one based on Artificial Intelligence. Both aim to…
Intracranial aneurysms (IAs) are abnormal dilations of cerebral blood vessels that, if ruptured, can lead to life-threatening consequences. However, their small size and soft contrast in radiological scans often make it difficult to perform…
Hypertrophic cardiomyopathy (HCM) patients have a high incidence of atrial fibrillation (AF) and increased stroke risk, even with low risk of congestive heart failure, hypertension, age, diabetes, previous stroke/transient ischemic attack…
Aortic valve stenosis (AVS) presents challenges in asymptomatic detection, resulting in delayed intervention. This study aims to understand how AVS affects pulse wave (PW) morphology. A PW database of 16,038 virtual subjects aged 50 to 75…