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Related papers: Brain Age Estimation with a Greedy Dual-Stream Mod…

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Simulating prospective magnetic resonance imaging (MRI) scans from a given individual brain image is challenging, as it requires accounting for canonical changes in aging and/or disease progression while also considering the individual…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Jingru Fu , Yuqi Zheng , Neel Dey , Daniel Ferreira , Rodrigo Moreno

Machine learning models for continuous outcomes often yield systematically biased predictions, particularly for values that largely deviate from the mean. Specifically, predictions for large-valued outcomes tend to be negatively biased…

Machine Learning · Statistics 2024-09-05 Hwiyoung Lee , Shuo Chen

Deep neural networks (DNN) have been designed to predict the chronological age of a healthy brain from T1-weighted magnetic resonance images (T1 MRIs), and the predicted brain age could serve as a valuable biomarker for the early detection…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Yu Fu , Yanyan Huang , Shunjie Dong , Yalin Wang , Tianbai Yu , Meng Niu , Cheng Zhuo

This paper presents a general framework for obtaining interpretable multivariate discriminative models that allow efficient statistical inference for neuroimage analysis. The framework, termed generative discriminative machine (GDM),…

Applications · Statistics 2019-06-04 Erdem Varol , Aristeidis Sotiras , Ke Zeng , Christos Davatzikos

Most deep learning models for temporal regression directly output the estimation based on single input images, ignoring the relationships between different images. In this paper, we propose deep relation learning for regression, aiming to…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Sheng He , Yanfang Feng , P. Ellen Grant , Yangming Ou

Age is one of the major known risk factors for Alzheimer's Disease (AD). Detecting AD early is crucial for effective treatment and preventing irreversible brain damage. Brain age, a measure derived from brain imaging reflecting structural…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Jay Shah , Md Mahfuzur Rahman Siddiquee , Yi Su , Teresa Wu , Baoxin Li

Brain age is a critical measure that reflects the biological ageing process of the brain. The gap between brain age and chronological age, referred to as brain PAD (Predicted Age Difference), has been utilized to investigate…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Lemuel Puglisi , Alessia Rondinella , Linda De Meo , Francesco Guarnera , Sebastiano Battiato , Daniele Ravì

Deep Learning for neuroimaging data is a promising but challenging direction. The high dimensionality of 3D MRI scans makes this endeavor compute and data-intensive. Most conventional 3D neuroimaging methods use 3D-CNN-based architectures…

Image and Video Processing · Electrical Eng. & Systems 2021-02-10 Umang Gupta , Pradeep K. Lam , Greg Ver Steeg , Paul M. Thompson

Age is an important variable to describe the expected brain's anatomy status across the normal aging trajectory. The deviation from that normative aging trajectory may provide some insights into neurological diseases. In neuroimaging,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Accurate segmentation of brain tissues from MRI scans is critical for neuroscience and clinical applications, but achieving consistent performance across the human lifespan remains challenging due to dynamic, age-related changes in brain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yongheng Sun , Jun Shu , Jianhua Ma , Fan Wang

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

Methodology · Statistics 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

Availability of large and diverse medical datasets is often challenged by privacy and data sharing restrictions. For successful application of machine learning techniques for disease diagnosis, prognosis, and precision medicine, large…

Age is an essential factor in modern diagnostic procedures. However, assessment of the true biological age (BA) remains a daunting task due to the lack of reference ground-truth labels. Current BA estimation approaches are either restricted…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Karim Armanious , Sherif Abdulatif , Wenbin Shi , Tobias Hepp , Sergios Gatidis , Bin Yang

Predictive modeling using structural magnetic resonance imaging (MRI) data is a prominent approach to study brain-aging. Machine learning algorithms and feature extraction methods have been employed to improve predictions and explore…

Machine Learning · Computer Science 2025-01-20 Georgios Antonopoulos , Shammi More , Simon B. Eickhoff , Federico Raimondo , Kaustubh R. Patil

Facial age estimation has received a lot of attention for its diverse application scenarios. Most existing studies treat each sample equally and aim to reduce the average estimation error for the entire dataset, which can be summarized as…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Zenghao Bao , Zichang Tan , Jun Li , Jun Wan , Xibo Ma , Zhen Lei

Neurodegeneration, characterized by the progressive loss of neuronal structure or function, is commonly assessed in clinical practice through reductions in cortical thickness or brain volume, as visualized by structural MRI. While…

Signal Processing · Electrical Eng. & Systems 2025-10-15 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

The shared response model provides a simple but effective framework to analyse fMRI data of subjects exposed to naturalistic stimuli. However when the number of subjects or runs is large, fitting the model requires a large amount of memory…

Computer Vision and Pattern Recognition · Computer Science 2019-12-04 Hugo Richard , Lucas Martin , Ana Luısa Pinho , Jonathan Pillow , Bertrand Thirion

Defining vascular age in terms of physiological function has become one focal point of the extensive studies to categorize and track chronological age. Transcranial Doppler (TCD) is a method by which cerebral blood flow velocity is measured…

Artificial Intelligence · Computer Science 2026-05-19 Anni Zhao , Alex Bateh , Tyler Baldridge , Sandra Billinger , Xiao Hu

Automatic segmentation of brain MR images into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) is critical for tissue volumetric analysis and cortical surface reconstruction. Due to dramatic structural and appearance…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Xiaoyang Chen , Jinjian Wu , Wenjiao Lyu , Yicheng Zou , Kim-Han Thung , Siyuan Liu , Ye Wu , Sahar Ahmad , Pew-Thian Yap

Deep learning can provide rapid brain age estimation based on brain magnetic resonance imaging (MRI). However, most studies use one neural network to extract the global information from the whole input image, ignoring the local fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Sheng He , P. Ellen Grant , Yangming Ou