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Developing efficient multi-objective optimization methods to compute the Pareto set of optimal compromises between conflicting objectives remains a key challenge, especially for large-scale and expensive problems. To bridge this gap, we…

Machine Learning · Computer Science 2026-02-05 Sedjro Salomon Hotegni , Sebastian Peitz

Diffusion models have demonstrated significant promise in various generative tasks; however, they often struggle to satisfy challenging constraints. Our approach addresses this limitation by rethinking training-free loss-guided diffusion…

Machine Learning · Computer Science 2024-11-19 William Huang , Yifeng Jiang , Tom Van Wouwe , C. Karen Liu

Offline multi-objective optimization aims to identify Pareto-optimal solutions given a dataset of designs and their objective values. In this work, we propose a preference-guided diffusion model that generates Pareto-optimal designs by…

Machine Learning · Computer Science 2025-12-19 Yashas Annadani , Syrine Belakaria , Stefano Ermon , Stefan Bauer , Barbara E Engelhardt

Building world models that accurately and comprehensively represent the real world is the utmost aspiration for conditional image generative models as it would enable their use as world simulators. For these models to be successful world…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Pietro Astolfi , Marlene Careil , Melissa Hall , Oscar Mañas , Matthew Muckley , Jakob Verbeek , Adriana Romero Soriano , Michal Drozdzal

Discrete diffusion models generate sequences by iteratively denoising samples corrupted by categorical noise, offering an appealing alternative to autoregressive decoding for structured and symbolic generation. However, standard training…

Machine Learning · Computer Science 2026-02-04 Huu Binh Ta , Michael Cardei , Alvaro Velasquez , Ferdinando Fioretto

AI-driven design problems, such as DNA/protein sequence design, are commonly tackled from two angles: generative modeling, which efficiently captures the feasible design space (e.g., natural images or biological sequences), and model-based…

To fully leverage the capabilities of diffusion models, we are often interested in optimizing downstream reward functions during inference. While numerous algorithms for reward-guided generation have been recently proposed due to their…

Machine Learning · Computer Science 2025-04-18 Masatoshi Uehara , Xingyu Su , Yulai Zhao , Xiner Li , Aviv Regev , Shuiwang Ji , Sergey Levine , Tommaso Biancalani

In light of the widespread success of generative models, a significant amount of research has gone into speeding up their sampling time. However, generative models are often sampled multiple times to obtain a diverse set incurring a cost…

Machine Learning · Computer Science 2023-11-27 Gabriele Corso , Yilun Xu , Valentin de Bortoli , Regina Barzilay , Tommi Jaakkola

Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Theodoros Kouzelis , Efstathios Karypidis , Ioannis Kakogeorgiou , Spyros Gidaris , Nikos Komodakis

Designing functional protein sequences that satisfy multiple desired properties is a core research focus of protein engineering. Prior methods struggle with inability or inefficiency when dealing with numerous, often conflicting,…

Biomolecules · Quantitative Biology 2026-05-08 Zitai Kong , Yifan Dong , Yixuan Wu , Zhaokang Liang , Jian Wu , Hongxia Xu

Modifications to test-time sampling have emerged as an important extension to diffusion algorithms, with the goal of biasing the generative process to achieve a given objective without having to retrain the entire diffusion model. However,…

Machine Learning · Computer Science 2026-04-21 Hao Luan , Yi Xian Goh , See-Kiong Ng , Chun Kai Ling

Recent advances in diffusion generative models have yielded remarkable progress. While the quality of generated content continues to improve, these models have grown considerably in size and complexity. This increasing computational burden…

Machine Learning · Computer Science 2025-03-13 Reza Shirkavand , Peiran Yu , Shangqian Gao , Gowthami Somepalli , Tom Goldstein , Heng Huang

This paper introduces an approach to endow generative diffusion processes the ability to satisfy and certify compliance with constraints and physical principles. The proposed method recast the traditional sampling process of generative…

Machine Learning · Computer Science 2024-11-05 Jacob K Christopher , Stephen Baek , Ferdinando Fioretto

Multi-objective optimization (MOO) arises in many real-world applications where trade-offs between competing objectives must be carefully balanced. In the offline setting, where only a static dataset is available, the main challenge is…

Machine Learning · Computer Science 2026-02-16 Jatan Shrestha , Santeri Heiskanen , Kari Hepola , Severi Rissanen , Pekka Jääskeläinen , Joni Pajarinen

Fine-tuning diffusion models via online reinforcement learning (RL) has shown great potential for enhancing text-to-image alignment. However, since precisely specifying a ground-truth objective for visual tasks remains challenging, the…

Machine Learning · Computer Science 2026-01-01 Haoran He , Yuxiao Ye , Jie Liu , Jiajun Liang , Zhiyong Wang , Ziyang Yuan , Xintao Wang , Hangyu Mao , Pengfei Wan , Ling Pan

Prototypical-part methods, e.g., ProtoPNet, enhance interpretability in image recognition by linking predictions to training prototypes, thereby offering intuitive insights into their decision-making. Existing methods, which rely on a…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Chong Wang , Yuanhong Chen , Fengbei Liu , Yuyuan Liu , Davis James McCarthy , Helen Frazer , Gustavo Carneiro

Diffusion generative models transform noise into data by inverting a process that progressively adds noise to data samples. Inspired by concepts from the renormalization group in physics, which analyzes systems across different scales, we…

Machine Learning · Computer Science 2024-10-04 Mathis Gerdes , Max Welling , Miranda C. N. Cheng

Diffusion models have emerged as effective tools for generating diverse and high-quality content. However, their capability in high-resolution image generation, particularly for panoramic images, still faces challenges such as visible seams…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Teng Zhou , Yongchuan Tang

Generative diffusion models trained on large-scale datasets have achieved remarkable progress in image synthesis. In favor of their ability to supplement missing details and generate aesthetically pleasing contents, recent works have…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Junhao Cheng , Wei-Ting Chen , Xi Lu , Ming-Hsuan Yang

Diffusion models have become a central tool in deep generative modeling, but standard formulations rely on a single network and a single diffusion schedule to transform a simple prior, typically a standard normal distribution, into the…

Machine Learning · Statistics 2025-12-29 Takuro Kutsuna
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