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Several enhanced sampling techniques rely on the definition of collective variables to effectively explore free energy landscapes. Existing variables that describe the progression along a reactive pathway offer an elegant solution but face…

Chemical Physics · Physics 2024-02-05 Thorben Fröhlking , Luigi Bonati , Valerio Rizzi , Francesco Luigi Gervasio

A variety of enhanced sampling methods predict multidimensional free energy landscapes associated with biological and other molecular processes as a function of a few selected collective variables (CVs). The accuracy of these methods is…

Computational Physics · Physics 2024-04-09 Lukas Müllender , Andrea Rizzi , Michele Parrinello , Paolo Carloni , Davide Mandelli

Accurately modeling quantum dissipative dynamics remains challenging due to environmental complexity and non-Markovian memory effects. Although machine learning provides a promising alternative to conventional simulation techniques, most…

Chemical Physics · Physics 2026-03-18 Muhammad Atif , Arif Ullah , Ming Yang

High-dimensional metastable molecular system can often be characterised by a few features of the system, i.e. collective variables (CVs). Thanks to the rapid advance in the area of machine learning and deep learning, various deep…

Machine Learning · Computer Science 2023-08-10 Wei Zhang , Christof Schütte

Investigating processes in complex molecular systems, which are characterized by many variables, is a crucial problem in computational physics. These systems can be reduced to a few meaningful degrees of freedom known as collective…

Chemical Physics · Physics 2024-05-27 Tuğçe Gökdemir , Jakub Rydzewski

In this work, we introduce DeepFlame, an open-source C++ platform with the capabilities of utilising machine learning algorithms and pre-trained models to solve for reactive flows. We combine the individual strengths of the computational…

Fluid Dynamics · Physics 2023-07-17 Runze Mao , Minqi Lin , Yan Zhang , Tianhan Zhang , Zhi-Qin John Xu , Zhi X. Chen

This paper explores the use of knowledge distillation to improve a Multi-Task Deep Neural Network (MT-DNN) (Liu et al., 2019) for learning text representations across multiple natural language understanding tasks. Although ensemble learning…

Computation and Language · Computer Science 2019-04-23 Xiaodong Liu , Pengcheng He , Weizhu Chen , Jianfeng Gao

We tackle the long-tailed visual recognition problem from the knowledge distillation perspective by proposing a Distill the Virtual Examples (DiVE) method. Specifically, by treating the predictions of a teacher model as virtual examples, we…

Computer Vision and Pattern Recognition · Computer Science 2021-09-21 Yin-Yin He , Jianxin Wu , Xiu-Shen Wei

Road lanes are integral components of the visual perception systems in intelligent vehicles, playing a pivotal role in safe navigation. In lane detection tasks, balancing accuracy with real-time performance is essential, yet existing…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Weiqing Qi , Guoyang Zhao , Fulong Ma , Linwei Zheng , Ming Liu

Recent advances in large-scale visual representation learning have significantly improved performance in plant species and plant disease recognition tasks. However, state-of-the-art models, often based on high-capacity vision transformers…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Ilyass Moummad , Reda Bensaid , Kawtar Zaher , Hervé Goëau , Jean-Christophe Lombardo , Joseph Salmon , Pierre Bonnet , Alexis Joly

The study of the rare transitions that take place between long lived metastable states is a major challenge in molecular dynamics simulations. Many of the methods suggested to address this problem rely on the identification of the slow…

Chemical Physics · Physics 2023-06-07 Dhiman Ray , Enrico Trizio , Michele Parrinello

Recent advances in graph neural networks (GNNs) have enabled more comprehensive modeling of molecules and molecular systems, thereby enhancing the precision of molecular property prediction and molecular simulations. Nonetheless, as the…

Machine Learning · Computer Science 2023-10-31 Filip Ekström Kelvinius , Dimitar Georgiev , Artur Petrov Toshev , Johannes Gasteiger

Distributed quantum machine learning faces significant challenges due to heterogeneous client data and variations in local model structures, which hinder global model aggregation. To address these challenges, we propose a knowledge…

Quantum Physics · Physics 2025-09-23 Kai Yu , Binbin Cai , Song Lin

This paper discusses our proposal and implementation of Distill, a domain-specific compilation tool based on LLVM to accelerate cognitive models. Cognitive models explain the process of cognitive function and offer a path to human-like…

Programming Languages · Computer Science 2022-01-17 Jan Vesely , Raghavendra Pradyumna Pothukuchi , Ketaki Joshi , Samyak Gupta , Jonathan D. Cohen , Abhishek Bhattacharjee

Many biological processes occur on time scales longer than those accessible to molecular dynamics simulations. Identifying collective variables (CVs) and introducing an external potential to accelerate them is a popular approach to address…

Computational Physics · Physics 2024-10-24 Enrico Trizio , Andrea Rizzi , Pablo M. Piaggi , Michele Invernizzi , Luigi Bonati

Macromolecular and biomolecular folding landscapes typically contain high free energy barriers that impede efficient sampling of configurational space by standard molecular dynamics simulation. Biased sampling can artificially drive the…

Biological Physics · Physics 2018-11-01 Wei Chen , Andrew L Ferguson

Deep Neural Networks (DNNs) have significantly advanced the field of computer vision. To improve DNN training process, knowledge distillation methods demonstrate their effectiveness in accelerating network training by introducing a fixed…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Daqian Shi , Xiaolei Diao , Xu Chen , Cédric M. John

Neural network potentials (NNPs) offer a powerful alternative to traditional force fields for molecular dynamics (MD) simulations. Accurate and stable MD simulations, crucial for evaluating material properties, require training data…

Machine Learning · Computer Science 2025-06-23 Naoki Matsumura , Yuta Yoshimoto , Yuto Iwasaki , Meguru Yamazaki , Yasufumi Sakai

Quantum Neural Networks (QNNs) are a promising class of quantum machine learning models with potential quantum advantages when implemented on scalable, error-corrected quantum computers. However, as system sizes increase, deploying QNNs…

Quantum Physics · Physics 2026-03-24 Yuxuan Yan , Sitian Qian , Qi Zhao , Xingjian Zhang

Understanding the long-time dynamics of complex physical processes depends on our ability to recognize patterns. To simplify the description of these processes, we often introduce a set of reaction coordinates, customarily referred to as…

Chemical Physics · Physics 2024-12-31 Tuğçe Gökdemir , Jakub Rydzewski
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