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RNA inverse folding, designing sequences to form specific 3D structures, is critical for therapeutics, gene regulation, and synthetic biology. Current methods, focused on sequence recovery, struggle to address structural objectives like…

Machine Learning · Computer Science 2026-01-28 Qi Si , Xuyang Liu , Penglei Wang , Xin Guo , Yuan Qi , Yuan Cheng

In sequential decision-making problems, Return-Conditioned Supervised Learning (RCSL) has gained increasing recognition for its simplicity and stability in modern decision-making tasks. Unlike traditional offline reinforcement learning (RL)…

Machine Learning · Computer Science 2025-06-11 Zhishuai Liu , Yu Yang , Ruhan Wang , Pan Xu , Dongruo Zhou

Reinforcement Learning (RL) is notoriously data-inefficient, which makes training on a real robot difficult. While model-based RL algorithms (world models) improve data-efficiency to some extent, they still require hours or days of…

Machine Learning · Computer Science 2023-10-25 Yunhai Feng , Nicklas Hansen , Ziyan Xiong , Chandramouli Rajagopalan , Xiaolong Wang

We seek to understand what facilitates sample-efficient learning from historical datasets for sequential decision-making, a problem that is popularly known as offline reinforcement learning (RL). Further, we are interested in algorithms…

Machine Learning · Computer Science 2024-02-07 Thanh Nguyen-Tang , Raman Arora

Data corruption, including missing and noisy data, poses significant challenges in real-world machine learning. This study investigates the effects of data corruption on model performance and explores strategies to mitigate these effects…

Machine Learning · Computer Science 2025-05-22 Qi Liu , Wanjing Ma

Offline Reinforcement Learning (RL) aims to turn large datasets into powerful decision-making engines without any online interactions with the environment. This great promise has motivated a large amount of research that hopes to replicate…

Machine Learning · Computer Science 2020-12-01 Louis Monier , Jakub Kmec , Alexandre Laterre , Thomas Pierrot , Valentin Courgeau , Olivier Sigaud , Karim Beguir

Deep reinforcement learning (DRL) requires the collection of interventional data, which is sometimes expensive and even unethical in the real world, such as in the autonomous driving and the medical field. Offline reinforcement learning…

Machine Learning · Computer Science 2023-06-12 Wenxuan Zhu , Chao Yu , Qiang Zhang

Pretraining reinforcement learning (RL) models on offline datasets is a promising way to improve their training efficiency in online tasks, but challenging due to the inherent mismatch in dynamics and behaviors across various tasks. We…

Machine Learning · Computer Science 2024-06-06 Minting Pan , Yitao Zheng , Yunbo Wang , Xiaokang Yang

Deep reinforcement learning algorithms that learn policies by trial-and-error must learn from limited amounts of data collected by actively interacting with the environment. While many prior works have shown that proper regularization…

Machine Learning · Computer Science 2023-04-21 Qiyang Li , Aviral Kumar , Ilya Kostrikov , Sergey Levine

Deep reinforcement learning (DRL) techniques have become increasingly used in various fields for decision-making processes. However, a challenge that often arises is the trade-off between both the computational efficiency of the…

Machine Learning · Computer Science 2023-08-21 Anthony Kobanda , Valliappan C. A. , Joshua Romoff , Ludovic Denoyer

This study tackles the challenges of adversarial corruption in model-based reinforcement learning (RL), where the transition dynamics can be corrupted by an adversary. Existing studies on corruption-robust RL mostly focus on the setting of…

Machine Learning · Statistics 2024-07-23 Chenlu Ye , Jiafan He , Quanquan Gu , Tong Zhang

Inductive reasoning, a cornerstone of human cognition, enables generalization from limited data but hasn't yet been fully achieved by large language models (LLMs). While modern LLMs excel at reasoning tasks, their ability to maintain stable…

Artificial Intelligence · Computer Science 2025-05-29 Chunyang Li , Weiqi Wang , Tianshi Zheng , Yangqiu Song

Long-sequence decision-making, which is usually addressed through reinforcement learning (RL), is a critical component for optimizing strategic operations in dynamic environments, such as real-time bidding in computational advertising. The…

Artificial Intelligence · Computer Science 2026-01-16 Xiaowei Lv , Zhilin Zhang , Yijun Li , Yusen Huo , Siyuan Ju , Xuyan Li , Chunxiang Hong , Tianyu Wang , Yongcai Wang , Peng Sun , Chuan Yu , Jian Xu , Bo Zheng

Decision Transformer (DT) can learn effective policy from offline datasets by converting the offline reinforcement learning (RL) into a supervised sequence modeling task, where the trajectory elements are generated auto-regressively…

Machine Learning · Computer Science 2024-11-19 Zhihong Liu , Long Qian , Zeyang Liu , Lipeng Wan , Xingyu Chen , Xuguang Lan

Offline reinforcement learning (RL), also known as batch RL, offers the prospect of policy optimization from large pre-recorded datasets without online environment interaction. It addresses challenges with regard to the cost of data…

Offline reinforcement learning (RL) refers to the problem of learning policies from a static dataset of environment interactions. Offline RL enables extensive use and re-use of historical datasets, while also alleviating safety concerns…

Machine Learning · Computer Science 2020-12-22 Rafael Rafailov , Tianhe Yu , Aravind Rajeswaran , Chelsea Finn

Diffusion models have shown strong competitiveness in offline reinforcement learning tasks by formulating decision-making as sequential generation. However, the practicality of these methods is limited due to the lengthy inference processes…

Machine Learning · Computer Science 2024-07-24 Renming Huang , Yunqiang Pei , Guoqing Wang , Yangming Zhang , Yang Yang , Peng Wang , Hengtao Shen

The learning inefficiency of reinforcement learning (RL) from scratch hinders its practical application towards continuous robotic tracking control, especially for high-dimensional robots. This work proposes a data-informed residual…

Systems and Control · Electrical Eng. & Systems 2024-06-10 Cong Li , Fangzhou Liu , Yongchao Wang , Martin Buss

Many cybersecurity problems that require real-time decision-making based on temporal observations can be abstracted as a sequence modeling problem, e.g., network intrusion detection from a sequence of arriving packets. Existing approaches…

Cryptography and Security · Computer Science 2023-12-19 Jingdi Chen , Hanhan Zhou , Yongsheng Mei , Gina Adam , Nathaniel D. Bastian , Tian Lan

Machine learning (ML) models trained using Empirical Risk Minimization (ERM) often exhibit systematic errors on specific subpopulations of tabular data, known as error slices. Learning robust representation in presence of error slices is…

Machine Learning · Computer Science 2025-11-10 Shantanu Ghosh , Tiankang Xie , Mikhail Kuznetsov