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The analysis of the tumor environment on digital histopathology slides is becoming key for the understanding of the immune response against cancer, supporting the development of novel immuno-therapies. We introduce here a novel deep…

Image and Video Processing · Electrical Eng. & Systems 2019-06-27 Ansh Kapil , Tobias Wiestler , Simon Lanzmich , Abraham Silva , Keith Steele , Marlon Rebelatto , Guenter Schmidt , Nicolas Brieu

We present a simulation method that allows us to calculate the titration curves for systems undergoing protonation/deprotonation reactions -- such as charged colloidal suspensions with acidic/basic surface groups, polyelectrolytes,…

Statistical Mechanics · Physics 2023-09-22 Yan Levin , Amin Bakhshandeh

We present a novel application of our high-resolution capacitance dilatometer, specifically engineered for the precise characterization of quantum materials. These materials, which often appear as ultrathin, platelet-shaped crystals, are…

Materials Science · Physics 2026-02-18 R. Küchler , S. Panja , S. Wirth , P. Gegenwart

Smartwatches have become popular for monitoring physiological parameters outside clinical settings. Using reflective photoplethysmography (PPG) sensors, such watches can non-invasively estimate heart rate (HR) in everyday environments and…

Signal Processing · Electrical Eng. & Systems 2024-12-24 Manuel Meier , Christian Holz

We present a detailed experimental study of the particle-hole symmetry (PHS) of the fractional quantum Hall (FQH) states about half filling in a multiband system. Specifically, we focus on the lowest Landau level of the monolayer-like band…

Mesoscale and Nanoscale Physics · Physics 2025-05-14 Simrandeep Kaur , Harsimran Singh , Kenji Watanabe , Takashi Taniguchi , Unmesh Ghorai , Manish Jain , Rajdeep Sensarma , Aveek Bid

H-score is a semi-quantitative method used to assess the presence and distribution of proteins in tissue samples by combining the intensity of staining and percentage of stained nuclei. It is widely used but time-consuming and can be…

Quantum entanglement is known as a unique quantum feature that cannot be obtained by classical physics. Over the last several decades, however, such an understanding on quantum entanglement might have confined us in a limited world of weird…

Quantum Physics · Physics 2023-08-01 B. S. Ham

Quantum entropies and state distances are analyzed in polaronic systems with short range (Holstein model) and long range (Fr$\ddot{o}$hlich model) electron-phonon coupling. These quantities are extracted by a variational wave function which…

Strongly Correlated Electrons · Physics 2015-05-19 C. A. Perroni , V. Marigliano Ramaglia , V. Cataudella

Topological phases are characterized by their entanglement properties, which is manifest in a direct relation between entanglement spectra and edge states discovered by Li and Haldane. We propose to leverage the power of synthetic quantum…

Quantum Gases · Physics 2022-05-04 Torsten V. Zache , Christian Kokail , Bhuvanesh Sundar , Peter Zoller

Quantum chemistry is envisioned as an early and disruptive application for quantum computers. Yet, closer scrutiny of the proposed algorithms shows that there are considerable difficulties along the way. Here, we propose two criteria for…

Quantum Physics · Physics 2026-04-09 Thibaud Louvet , Thomas Ayral , Xavier Waintal

Super-resolution microscopy has catalyzed valuable insights into the sub-cellular, mechanistic details of many different biological processes across a wide range of cell types. Fluorescence polarization spectroscopy tools have also enabled…

Biological Physics · Physics 2023-01-25 Jack W Shepherd , Alex L Payne-Dwyer , Ji-Eun Lee , Aisha Syeda , Mark C Leake

Using a field-portable, smartphone fluorometer to assess water quality based on the pH response of a designer probe, a map of pH of public tap water sites has been obtained. A custom designed Android application digitally processed and…

Instrumentation and Detectors · Physics 2015-10-27 Arafat Hossain , John Canning , Sandra Ast , Peter J. Rutledge , Abbas Jamalipour

The detection of organic molecules with increasing complexity and potential biological relevance is opening the possibility to understand the formation of the building blocks of life in the interstellar medium. One of the families of…

Astrophysics of Galaxies · Physics 2017-02-22 V. M. Rivilla , M. T. Beltrán , J. Martín-Pintado , F. Fontani , P. Caselli , R. Cesaroni

Entanglement is a fundamental resource of various optical quantum-information-processing (QIP) applications. Towards high-speed QIP system, entanglement should be encoded in short wavepackets. We report real-time observation of ultrafast…

Cytosine methylation has been found to play a crucial role in various biological processes, including a number of human diseases. The detection of this small modification remains challenging. In this work, we computationally explore the…

Biological Physics · Physics 2017-02-21 Jianqing Qi , Niranjan Govind , M. P. Anantram

Motivation: Bisulphite sequencing enables the detection of cytosine methylation. The sequence of the methylation states of cytosines on any given read forms a methylation pattern that carries substantially more information than merely…

Genomics · Quantitative Biology 2014-12-09 Peijie Lin , Sylvain Foret , Susan R. Wilson , Conrad J. Burden

For a long time, performing converged path integral simulations at ultra-low, but finite temperatures of a few Kelvin has been a nearly impossible task. However, recent developments in advanced colored noise thermostatting schemes for path…

Chemical Physics · Physics 2021-03-25 Christoph Schran , Fabien Brieuc , Dominik Marx

We propose a hybrid approach to the experimental assessment of the genuine quantum features of a general system consisting of microscopic and macroscopic parts. We infer entanglement by combining dichotomic measurements on a bidimensional…

All observations by the aperture photometer (PHT-P) and the far-infrared (FIR) camera section (PHT-C) of ISOPHOT included reference measurements against stable internal fine calibration sources (FCS) to correct for temporal drifts in…

High-resolution spatial transcriptomics (HR-ST) technologies offer unprecedented insights into tissue architecture but lack standardized frameworks for histological annotation. We present ST2HE, a cross-platform generative framework that…

Quantitative Methods · Quantitative Biology 2025-10-16 Zhentao Liu , Arun Das , Wen Meng , Yu-Chiao Chiu , Shou-Jiang Gao , Yufei Huang