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In genetical genomics studies, it is important to jointly analyze gene expression data and genetic variants in exploring their associations with complex traits, where the dimensionality of gene expressions and genetic variants can both be…

Methodology · Statistics 2014-04-15 Wei Lin , Rui Feng , Hongzhe Li

High-dimensional statistical inference deals with models in which the the number of parameters p is comparable to or larger than the sample size n. Since it is usually impossible to obtain consistent procedures unless $p/n\rightarrow0$, a…

Statistics Theory · Mathematics 2013-03-13 Sahand N. Negahban , Pradeep Ravikumar , Martin J. Wainwright , Bin Yu

Many data extraction tasks of practical relevance require not only syntactic pattern matching but also semantic reasoning about the content of the underlying text. While regular expressions are very well suited for tasks that require only…

Programming Languages · Computer Science 2023-08-28 Qiaochu Chen , Arko Banerjee , Çağatay Demiralp , Greg Durrett , Isil Dillig

Studies on generalization performance of machine learning algorithms under the scope of information theory suggest that compressed representations can guarantee good generalization, inspiring many compression-based regularization methods.…

Machine Learning · Computer Science 2019-10-16 Antoine Saporta , Yifu Chen , Michael Blot , Matthieu Cord

Modern technologies are producing a wealth of data with complex structures. For instance, in two-dimensional digital imaging, flow cytometry, and electroencephalography, matrix type covariates frequently arise when measurements are obtained…

Methodology · Statistics 2013-10-22 Hua Zhou , Lexin Li

Within the statistical and machine learning literature, regularization techniques are often used to construct sparse (predictive) models. Most regularization strategies only work for data where all predictors are treated identically, such…

Computation · Statistics 2020-12-16 Sander Devriendt , Katrien Antonio , Tom Reynkens , Roel Verbelen

Synthetic data can improve generalization when real data is scarce, but excessive reliance may introduce distributional mismatches that degrade performance. In this paper, we present a learning-theoretic framework to quantify the trade-off…

Machine Learning · Statistics 2026-04-02 Amitis Shidani , Tyler Farghly , Yang Sun , Habib Ganjgahi , George Deligiannidis

Latent variable models are a fundamental modeling tool in machine learning applications, but they present significant computational and analytical challenges. The popular EM algorithm and its variants, is a much used algorithmic tool; yet…

Machine Learning · Computer Science 2015-12-08 Xinyang Yi , Constantine Caramanis

Gene expression analysis aims at identifying the genes able to accurately predict biological parameters like, for example, disease subtyping or progression. While accurate prediction can be achieved by means of many different techniques,…

Methodology · Statistics 2008-09-11 Christine De Mol , Sofia Mosci , Magali Traskine , Alessandro Verri

Empirical Risk Minimization (ERM) algorithms are widely used in a variety of estimation and prediction tasks in signal-processing and machine learning applications. Despite their popularity, a theory that explains their statistical…

Machine Learning · Statistics 2020-07-07 Hossein Taheri , Ramtin Pedarsani , Christos Thrampoulidis

Many statistical estimators for high-dimensional linear regression are M-estimators, formed through minimizing a data-dependent square loss function plus a regularizer. This work considers a new class of estimators implicitly defined…

Statistics Theory · Mathematics 2022-02-15 Peng Zhao , Yun Yang , Qiao-Chu He

Recently, a large number of efficient deep learning methods for solving inverse problems have been developed and show outstanding numerical performance. For these deep learning methods, however, a solid theoretical foundation in the form of…

Numerical Analysis · Mathematics 2020-02-04 Daniel Obmann , Johannes Schwab , Markus Haltmeier

When solving rank-deficient or discrete ill-posed problems by regularization methods, the choice of the regularization parameter is crucial. It is also of interest, the regularization norm used in the selection of the solution. In this…

Numerical Analysis · Mathematics 2024-10-30 Ibrahima Dione

Elasticity image, visualizing the quantitative map of tissue stiffness, can be reconstructed by solving an inverse problem. Classical methods for magnetic resonance elastography (MRE) try to solve a regularized optimization problem…

Image and Video Processing · Electrical Eng. & Systems 2021-05-28 Narges Mohammadi , Marvin M. Doyley , Mujdat Cetin

Modelling statistical relationships beyond the conditional mean is crucial in many settings. Conditional density estimation (CDE) aims to learn the full conditional probability density from data. Though highly expressive, neural network…

Machine Learning · Statistics 2020-02-17 Jonas Rothfuss , Fabio Ferreira , Simon Boehm , Simon Walther , Maxim Ulrich , Tamim Asfour , Andreas Krause

In this paper, we study the effect of different regularizers and their implications in high dimensional image classification and sparse linear unmixing. Although kernelization or sparse methods are globally accepted solutions for processing…

Machine Learning · Statistics 2016-11-03 Devis Tuia , Remi Flamary , Michel Barlaud

High-dimensional sparse modeling via regularization provides a powerful tool for analyzing large-scale data sets and obtaining meaningful, interpretable models. The use of nonconvex penalty functions shows advantage in selecting important…

Methodology · Statistics 2016-05-12 Zemin Zheng , Yingying Fan , Jinchi Lv

Linear Mixed-Effects (LME) models are a fundamental tool for modeling correlated data, including cohort studies, longitudinal data analysis, and meta-analysis. Design and analysis of variable selection methods for LMEs is more difficult…

We introduce Stochastic Asymptotical Regularization (SAR) methods for the uncertainty quantification of the stable approximate solution of ill-posed linear-operator equations, which are deterministic models for numerous inverse problems in…

Numerical Analysis · Mathematics 2022-12-21 Ye Zhang , Chuchu Chen

Regularization is widely used in statistics and machine learning to prevent overfitting and gear solution towards prior information. In general, a regularized estimation problem minimizes the sum of a loss function and a penalty term. The…

Computation · Statistics 2012-01-18 Hua Zhou , Yichao Wu
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