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Related papers: Towards an Innate Cell-Environment Nanothermometer

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The temperature distribution within cells, especially the debates on mitochondrial temperature, has recently attracted widespread attention. Some studies have claimed that the temperature of mitochondria can reach up to 50-53 degrees…

Biological Physics · Physics 2025-06-03 Tong Zhang , Tian-Tian Li , Jing-Ru Wang , Yu-Wen Zhang , Chao Sun , Zheng Huang , Jing-Juan Xu , Bin Kang

Cell-based biosensors constitute a fundamental tool in biotechnology, and their relevance has greatly increased in recent years as a result of a surging demand for reduced animal testing and for high-throughput and cost-effective in vitro…

Energy dissipation is a fundamental process governing the dynamics of physical, chemical, and biological systems. It is also one of the main characteristics distinguishing quantum and classical phenomena. In condensed matter physics, in…

Fluorescent nanothermometry has revealed pronounced intracellular temperature heterogeneity, establishing the field of single-cell thermal biology. However, these observations have sparked a controversy known as the "10^5 gap issue",…

The local thermal conductivity (\k{appa}) is a pivotal biophysical parameter, governing intracellular heat flux and underlying functional processes like metabolic regulation and stress response. However, label-free mapping with sub-micron…

Biological Physics · Physics 2026-03-04 Jiahua Zhang , Yong Hou , Xinhao Hu , Yicheng Wang , Madoka Suzuki , Bo Gao , Zhiqin Chu

To achieve accurate results in nanocalorimetry a detailed analysis and understanding of the behavior of the calorimetric system is required. There are especially two system-related aspects that should be taken in consideration: the…

Other Condensed Matter · Physics 2012-03-12 S. Tagliati , A. Rydh

Extracellular protein concentrations and gradients queue a wide range of cellular responses, such as cell motility and division. Spatio-temporal quantification of these concentrations as produced by cells has proven challenging. As a…

Quantitative Methods · Quantitative Biology 2015-05-12 Jeff M. Byers , Joseph A. Christodoulides , James B. Delehanty , Deepa Raghu , Marc P. Raphael

Accurate temperature measurement at the nanoscale is crucial for thermal management in next-generation microelectronic devices. Existing optical and scanning-probe thermometry techniques face limitations in spatial resolution, accuracy, or…

Understanding heat transport is relevant to develop efficient strategies for thermal management in microelectronics for instance, as well as for fundamental science purposes. However, measuring temperatures in nanostructured environments…

The use of gold nanoparticles for hyperthermia therapy in near infrared (NIR) spectral regions has catalysed substantial research efforts due to the potential impact in clinical therapy applications. However, the photoscattering effect…

We report on three new types of nanoelectromechanical systems based on carbon nanotubes: an electromechanical nanothermometer, a nanorelay and a nanomotor. The nanothermometer can be used for accurate temperature measurements in spatially…

Other Condensed Matter · Physics 2015-05-13 Andrey M. Popov , Yurii E. Lozovik , Elena Bichoutskaia , Anton S. Kulish

A differential, membrane-based nanocalorimeter for general specific heat studies of very small samples, ranging from 0.5 mg to sub-{\mu}g in mass, is described. The calorimeter operates over the temperature range from above room temperature…

Instrumentation and Detectors · Physics 2012-08-20 S. Tagliati , V. M. Krasnov , A. Rydh

Over the last decade, single-molecule optical microscopy has become the gold-standard approach to decipher complex molecular processes in cellular environments. [1-3] Single-molecule fluorescence microscopy has several advantages such as…

Biological Physics · Physics 2017-11-15 Edakkattuparambil Sidharth Shibu , Nadezda Varkentina , Laurent Cognet , Brahim Lounis

The femtosecond evolution of the electronic temperature of laser-excited gold nanoparticles is measured, by means of ultrafast time-resolved photoemission spectroscopy induced by extreme-ultraviolet radiation pulses. The temperature of the…

Nanophotonic engineering of light-matter interaction at subwavelength scale allows thermal radiation that is fundamentally different from that of traditional thermal emitters and provides exciting opportunities for various thermal-photonic…

Electron microscopy (EM) has been instrumental in our understanding of biological systems ranging from subcellular structures to complex organisms. Although EM reveals cellular morphology with nanoscale resolution, it does not provide…

The achievement of all-fibre functional nano-modules for subcellular label-free measurement has long been pursued due to the limitations of manufacturing techniques. In this paper, a compact all-fibre label-free nano-sensor composed of a…

Motivated by the recent development of fast and ultra-sensitive thermometry in nanoscale systems, we investigate quantum calorimetric detection of individual heat pulses in the sub-meV energy range. We propose a hybrid superconducting…

Mesoscale and Nanoscale Physics · Physics 2018-11-28 F. Brange , P. Samuelsson , B. Karimi , J. P. Pekola

We explore the possibility to perform an in-situ transmission electron microscopy (TEM) thermoelectric characterization of materials. A differential heating element on a custom in-situ TEM microchip allows to generate a temperature gradient…

Materials Science · Physics 2025-01-14 Simon Hettler , Mohammad Furqan , Andres Sotelo , Raul Arenal

The reliable measurement and accurate control of the temperature within nanophotonic devices is a key prerequisite for their application in both classical and quantum technologies. Established approaches use sensors that are attached in…

Quantum Physics · Physics 2025-02-19 Kilian Sandholzer , Stephan Rinner , Justus Edelmann , Andreas Reiserer