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The adoption of digital twins (DTs) in precision medicine is increasingly viable, propelled by extensive data collection and advancements in artificial intelligence (AI), alongside traditional biomedical methodologies. However, the reliance…

The report describes the discussions from the Workshop on Mathematical Opportunities in Digital Twins (MATH-DT) from December 11-13, 2023, George Mason University. It illustrates that foundational Mathematical advances are required for…

Optimization and Control · Mathematics 2024-03-25 Harbir Antil

Digital Twin technology is an emerging concept that has become the centre of attention for industry and, in more recent years, academia. The advancements in industry 4.0 concepts have facilitated its growth, particularly in the…

Computers and Society · Computer Science 2020-06-19 Aidan Fuller , Zhong Fan , Charles Day , Chris Barlow

Digital twin (DT) technology enables real-time simulation, prediction, and optimization of physical systems, but practical deployment faces challenges from high data requirements, proprietary data constraints, and limited adaptability to…

The use of a software tool chain to generate Digital Twins (DTs) automatically can speed up digitization and lower development costs. Engineering documents and system data are just two examples of source information that can be used to…

Human-Computer Interaction · Computer Science 2023-10-24 Mohammad Azangoo , Seppo Sierla , Valeriy Vyatkin

We live in a world of exploding complexity driven by technical evolution as well as highly volatile socio-economic environments. Managing complexity is a key issue in everyday decision making such as providing safe, sustainable, and…

Computers and Society · Computer Science 2023-11-28 Dirk Hartmann

Digital Twins have been described as beneficial in many areas, such as virtual commissioning, fault prediction or reconfiguration planning. Equipping Digital Twins with artificial intelligence functionalities can greatly expand those…

Machine Learning · Computer Science 2021-08-31 Benjamin Maschler , Dominik Braun , Nasser Jazdi , Michael Weyrich

A digital twin (DT) is a virtual representation of physical process, products and/or systems that requires a high-fidelity computational model for continuous update through the integration of sensor data and user input. In the context of…

Machine Learning · Computer Science 2023-11-15 Yangfan Li , Satyajit Mojumder , Ye Lu , Abdullah Al Amin , Jiachen Guo , Xiaoyu Xie , Wei Chen , Gregory J. Wagner , Jian Cao , Wing Kam Liu

The energy sector's digital transformation brings mutually dependent communication and energy infrastructure, tightening the relationship between the physical and the digital world. Digital twins (DT) are the key concept for this. This…

Systems and Control · Electrical Eng. & Systems 2025-03-19 Wouter Zomerdijk , Peter Palensky , Tarek AlSkaif , Pedro P. Vergara

A digital twin can be defined as an adaptive model of a complex physical system. Recent advances in computational pipelines, multiphysics solvers, artificial intelligence, big data cybernetics, data processing and management tools bring the…

Signal Processing · Electrical Eng. & Systems 2019-10-07 Adil Rasheed , Omer San , Trond Kvamsdal

The digital twin has emerged as a technology to predict the undesirables, and ensure desired performance of complex systems. Although digital twins have got attention in the manufacturing research spectrum, yet their industrial application…

Systems and Control · Electrical Eng. & Systems 2021-04-08 Ali Ahmad Malik

Over the years, Digital Twin (DT) has become popular in Advanced Manufacturing (AM) due to its ability to improve production efficiency and quality. By creating virtual replicas of physical assets, DTs help in real-time monitoring, develop…

Computational Engineering, Finance, and Science · Computer Science 2024-11-05 Chas Hamel , Md Manjurul Ahsan , Shivakumar Raman

Digital Twins (DTs) represent digital counterparts of physical systems, assets, or processes, referred to as the actual twin (AT). DTs integrate heterogeneous data, models, and semantic technologies to support monitoring, simulation,…

Software Engineering · Computer Science 2026-05-21 Faima Abbasi , Jean-Sébastien Sottet , Cedric Pruski

With the accelerating availability of multimodal surgical data and real-time computation, Surgical Digital Twins (SDTs) have emerged as virtual counterparts that mirror, predict, and inform decisions across pre-, intra-, and postoperative…

Digital twins are sophisticated software systems for the representation, monitoring, and control of cyber-physical systems, including automotive, avionics, smart manufacturing, and many more. Existing definitions and reference models of…

Software Engineering · Computer Science 2025-07-08 Jerome Pfeiffer , Jingxi Zhang , Benoit Combemale , Judith Michael , Bernhard Rumpe , Manuel Wimmer , Andreas Wortmann

Digital Twins (DTs) are set to become a key enabling technology in future wireless networks, with their use in network management increasing significantly. We developed a DT framework that leverages the heterogeneity of network access…

Networking and Internet Architecture · Computer Science 2024-08-07 Roberto Morabito , Bivek Pandey , Paulius Daubaris , Yasith R Wanigarathna , Sasu Tarkoma

Digital Twin was introduced over a decade ago, as an innovative all-encompassing tool, with perceived benefits including real-time monitoring, simulation and forecasting. However, the theoretical framework and practical implementations of…

Machine Learning · Computer Science 2020-12-07 Angira Sharma , Edward Kosasih , Jie Zhang , Alexandra Brintrup , Anisoara Calinescu

Modern manufacturing demands high flexibility and reconfigurability to adapt to dynamic production needs. Model-based Engineering (MBE) supports rapid production line design, but final reconfiguration requires simulations and validation.…

Digital twin (DT) technology has received immense attention over the years due to the promises it presents to various stakeholders in science and engineering. As a result, different thematic areas of DT have been explored. This is no…

Computational Engineering, Finance, and Science · Computer Science 2024-10-22 Taiwo A. Adebiyi , Nafeezat A. Ajenifuja , Ruda Zhang

The evolution of network virtualization and native artificial intelligence (AI) paradigms have conceptualized the vision of future wireless networks as a comprehensive entity operating in whole over a digital platform, with smart…

Artificial Intelligence · Computer Science 2023-03-30 Lina Bariah , Merouane Debbah