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Being able to successfully determine whether the testing samples has similar distribution as the training samples is a fundamental question to address before we can safely deploy most of the machine learning models into practice. In this…

Machine Learning · Computer Science 2024-05-07 Zhaiming Shen , Menglun Wang , Guang Cheng , Ming-Jun Lai , Lin Mu , Ruihao Huang , Qi Liu , Hao Zhu

Building robust deterministic neural networks remains a challenge. On the one hand, some approaches improve out-of-distribution detection at the cost of reducing classification accuracy in some situations. On the other hand, some methods…

Machine Learning · Computer Science 2022-08-09 David Macêdo , Cleber Zanchettin , Teresa Ludermir

Classifier-guided diffusion models have emerged as a powerful approach for conditional image generation, but they suffer from overconfident predictions during early denoising steps, causing the guidance gradient to vanish. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Seyed Alireza Javid , Amirhossein Bagheri , Nuria González-Prelcic

Despite multiple efforts made towards robust machine learning (ML) models, their vulnerability to adversarial examples remains a challenging problem that calls for rethinking the defense strategy. In this paper, we take a step back and…

Machine Learning · Computer Science 2022-02-21 Abderrahmen Amich , Birhanu Eshete

Out-of-distribution (OOD) detection in deep learning has traditionally been framed as a binary task, where samples are either classified as belonging to the known classes or marked as OOD, with little attention given to the semantic…

Machine Learning · Computer Science 2025-03-28 Erik Wallin , Fredrik Kahl , Lars Hammarstrand

Machine learning models are increasingly used in practice. However, many machine learning methods are sensitive to test or operational data that is dissimilar to training data. Out-of-distribution (OOD) data is known to increase the…

Machine Learning · Computer Science 2023-03-01 Tyler Cody , Laura Freeman

Out-of-Distribution (OOD) detection is critical for safe deployment; however, existing detectors often struggle to generalize across datasets of varying scales and model architectures, and some can incur high computational costs in…

Machine Learning · Computer Science 2025-04-04 Litian Liu , Yao Qin

Out-of-distribution (OoD) detection for data-based programs is a goal of paramount importance. Common approaches in the literature tend to train detectors requiring inside-of-distribution (in-distribution, or IoD) and OoD validation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 Romain Xu-Darme , Julien Girard-Satabin , Darryl Hond , Gabriele Incorvaia , Zakaria Chihani

The generalization ability of machine learning models degrades significantly when the test distribution shifts away from the training distribution. We investigate the problem of training models that are robust to shifts caused by changes in…

Machine Learning · Computer Science 2023-09-19 Jiaheng Wei , Harikrishna Narasimhan , Ehsan Amid , Wen-Sheng Chu , Yang Liu , Abhishek Kumar

Likelihood-based deep generative models (DGMs) have gained significant attention for their ability to approximate the distributions of high-dimensional data. However, these models lack a performance guarantee in assigning higher likelihood…

Machine Learning · Computer Science 2025-02-04 Behrooz Montazeran , Ullrich Köthe

How can we automatically select an out-of-distribution (OOD) detection model for various underlying tasks? This is crucial for maintaining the reliability of open-world applications by identifying data distribution shifts, particularly in…

Machine Learning · Computer Science 2025-03-03 Yuehan Qin , Yichi Zhang , Yi Nian , Xueying Ding , Yue Zhao

The function of biomolecules such as proteins depends on their ability to interconvert between a wide range of structures or "conformations." Researchers have endeavored for decades to develop computational methods to predict the…

Biomolecules · Quantitative Biology 2026-02-05 Daniel D. Richman , Jessica Karaguesian , Carl-Mikael Suomivuori , Ron O. Dror

Segmentation evaluation metrics traditionally rely on binary decision logic: predictions are either correct or incorrect, based on rigid IoU thresholds. Detection--based metrics such as F1 and mAP determine correctness at the object level…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Ranit Karmakar , Simon F. Nørrelykke

Reliable use of deep neural networks (DNNs) for medical image analysis requires methods to identify inputs that differ significantly from the training data, called out-of-distribution (OOD), to prevent erroneous predictions. OOD detection…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Harry Anthony , Konstantinos Kamnitsas

Estimating model accuracy on unseen, unlabeled datasets is crucial for real-world machine learning applications, especially under distribution shifts that can degrade performance. Existing methods often rely on predicted class probabilities…

Machine Learning · Computer Science 2025-08-28 Chenzhi Liu , Mahsa Baktashmotlagh , Yanran Tang , Zi Huang , Ruihong Qiu

Generalizing deep learning models to unknown target domain distribution with low latency has motivated research into test-time training/adaptation (TTT/TTA). Existing approaches often focus on improving test-time training performance under…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Yushu Li , Xun Xu , Yongyi Su , Kui Jia

Reliable confidence estimation for deep neural classifiers is a challenging yet fundamental requirement in high-stakes applications. Unfortunately, modern deep neural networks are often overconfident for their erroneous predictions. In this…

Machine Learning · Computer Science 2023-03-31 Fei Zhu , Zhen Cheng , Xu-Yao Zhang , Cheng-Lin Liu

Out-of-distribution (OOD) detection is a crucial part of deploying machine learning models safely. It has been extensively studied with a plethora of methods developed in the literature. This problem is tackled with an OOD score…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Jingqiu Zhou , Aojun Zhou , Hongsheng Li

Recent advancements have explored text-to-image diffusion models for synthesizing out-of-distribution (OOD) samples, substantially enhancing the performance of OOD detection. However, existing approaches typically rely on perturbing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Xin Gao , Jiyao Liu , Guanghao Li , Yueming Lyu , Jianxiong Gao , Weichen Yu , Ningsheng Xu , Liang Wang , Caifeng Shan , Ziwei Liu , Chenyang Si

Deep neural networks have significantly contributed to the success in predictive accuracy for classification tasks. However, they tend to make over-confident predictions in real-world settings, where domain shifting and out-of-distribution…

Artificial Intelligence · Computer Science 2021-07-16 Yibo Hu , Latifur Khan