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This study proposes a novel framework based on the RuleFit method to estimate Heterogeneous Treatment Effect (HTE) in a randomized clinical trial. To achieve this, we adopted S-learner of the metaalgorithm for our proposed framework. The…

Methodology · Statistics 2023-07-28 Mayu Hiraishi , Ke Wan , Kensuke Tanioka , Hiroshi Yadohisa , Toshio Shimokawa

Causal discovery algorithms aim at untangling complex causal relationships from data. Here, we study causal discovery and inference methods based on staged tree models, which can represent complex and asymmetric causal relationships between…

Methodology · Statistics 2023-03-02 Manuele Leonelli , Gherardo Varando

Many processes, from gene interaction in biology to computer networks to social media, can be modeled more precisely as temporal hypergraphs than by regular graphs. This is because hypergraphs generalize graphs by extending edges to connect…

Human-Computer Interaction · Computer Science 2021-05-12 Maximilian T. Fischer , Devanshu Arya , Dirk Streeb , Daniel Seebacher , Daniel A. Keim , Marcel Worring

Discovering a unique causal structure is difficult due to both inherent identifiability issues, and the consequences of finite data. As such, uncertainty over causal structures, such as those obtained from a Bayesian posterior, are often…

Machine Learning · Computer Science 2025-03-06 Anish Dhir , Matthew Ashman , James Requeima , Mark van der Wilk

We address the problem of estimating causal effects from observational data in the presence of network confounding, a setting where both treatment assignment and observed outcomes of individuals may be influenced by their neighbors within a…

Machine Learning · Computer Science 2026-03-24 Abhishek Dalvi , Neil Ashtekar , Vasant Honavar

Personalized healthcare decisions require reasoning about how physiological and behavioral variables influence an individual patient over time. Existing temporal causal discovery methods are poorly matched to this setting: cohort-level…

Machine Learning · Computer Science 2026-05-11 Elahe Khatibi , Ziyu Wang , Saba A. Farahani , Di Huang , Hung Cao , Ramesh Jain , Amir M. Rahmani

A fundamental task in science is to determine the underlying causal relations because it is the knowledge of this functional structure what leads to the correct interpretation of an effect given the apparent associations in the observed…

Artificial Intelligence · Computer Science 2024-08-02 Alexandre Trilla , Nenad Mijatovic

Causal discovery studies the problem of mining causal relationships between variables from data, which is of primary interest in science. During the past decades, significant amount of progresses have been made toward this fundamental data…

Artificial Intelligence · Computer Science 2016-11-28 Kui Yu , Jiuyong Li , Lin Liu

A number of methods have been proposed for causal effect estimation, yet few have demonstrated efficacy in handling data with complex structures, such as images. To fill this gap, we propose Causal Multi-task Deep Ensemble (CMDE), a novel…

Machine Learning · Computer Science 2023-05-30 Ziyang Jiang , Zhuoran Hou , Yiling Liu , Yiman Ren , Keyu Li , David Carlson

Causal discovery is a difficult problem that typically relies on strong assumptions on the data-generating model, such as non-Gaussianity. In practice, many modern applications provide multiple related views of the same system, which has…

Machine Learning · Computer Science 2025-09-29 Ambroise Heurtebise , Omar Chehab , Pierre Ablin , Alexandre Gramfort , Aapo Hyvärinen

Causal inference is a fundamental research topic for discovering the cause-effect relationships in many disciplines. However, not all algorithms are equally well-suited for a given dataset. For instance, some approaches may only be able to…

Machine Learning · Computer Science 2024-03-11 Zhipeng Ma , Marco Kemmerling , Daniel Buschmann , Chrismarie Enslin , Daniel Lütticke , Robert H. Schmitt

Meta-analysis, by synthesizing effect estimates from multiple studies conducted in diverse settings, stands at the top of the evidence hierarchy in clinical research. Yet, conventional approaches based on fixed- or random-effects models…

Understanding causal heterogeneity is essential for scientific discovery in domains such as biology and medicine. However, existing methods lack causal awareness, with insufficient modeling of heterogeneity, confounding, and observational…

Machine Learning · Computer Science 2025-10-29 Wenrui Li , Qinghao Zhang , Xiaowo Wang

The ability to understand causality from data is one of the major milestones of human-level intelligence. Causal Discovery (CD) algorithms can identify the cause-effect relationships among the variables of a system from related…

Artificial Intelligence · Computer Science 2024-03-14 Uzma Hasan , Emam Hossain , Md Osman Gani

We propose a novel method for estimating heterogeneous treatment effects based on the fused lasso. By first ordering samples based on the propensity or prognostic score, we match units from the treatment and control groups. We then run the…

Background: Selecting feature genes to predict phenotypes is one of the typical tasks in analyzing genomics data. Though many general-purpose algorithms were developed for prediction, dealing with highly correlated genes in the prediction…

Applications · Statistics 2022-04-11 Li Xing , Songwan Joun , Kurt Mackay , Mary Lesperance , Xuekui Zhang

Human activity recognition (HAR) is a key challenge in pervasive computing and its solutions have been presented based on various disciplines. Specifically, for HAR in a smart space without privacy and accessibility issues, data streams…

Machine Learning · Computer Science 2023-12-04 Hyunju Kim , Heesuk Son , Dongman Lee

Interpretability plays a crucial role in the application of statistical learning to estimate heterogeneous treatment effects (HTE) in complex diseases. In this study, we leverage a rule-based workflow, namely causal rule learning (CRL), to…

Machine Learning · Computer Science 2025-11-24 Ying Wu , Hanzhong Liu , Kai Ren , Shujie Ma , Xiangyu Chang

Predictive models learned from historical data are widely used to help companies and organizations make decisions. However, they may digitally unfairly treat unwanted groups, raising concerns about fairness and discrimination. In this…

Machine Learning · Computer Science 2018-03-07 Yongkai Wu , Lu Zhang , Xintao Wu

Causal effect estimation under observational studies is challenging due to the lack of ground truth data and treatment assignment bias. Though various methods exist in literature for addressing this problem, most of them ignore…

Artificial Intelligence · Computer Science 2024-12-11 Abhinav Thorat , Ravi Kolla , Niranjan Pedanekar
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