Related papers: The relationship between parameters and effects in…
The electroencephalography (EEG), which is one of the easiest modes of recording brain activations in a non-invasive manner, is often distorted due to recording artifacts which adversely impacts the stimulus-response analysis. The most…
Instrumental variables are commonly used to estimate effects of a treatment afflicted by unmeasured confounding, and in practice instruments are often continuous (e.g., measures of distance, or treatment preference). However, available…
Biophysical models describing complex, cellular phenomena typically include systems of nonlinear differential equations with many free parameters. While experimental measurements can fix some parameters, those describing internal cellular…
Noninvasive brain stimulation can activate neurons in the brain but requires power electronics with exceptionally high power in the mega-volt-ampere and high frequencies in the kilohertz range. Whereas oscillator circuits offered only one…
Pulse-modulated feedback is utilized in drug dosing to mimic sustained over a longer period of time manual discrete dose administration, the latter is in contrast with continuous drug infusion. The intermittent mode of dosing calls for a…
The present literature about possible mechanisms behind the effectivity of noninvasive electromagnetic stimulation in major depressive disorder (MDD) is not very rich. Despite extensive research in applications for clinical practice, the…
Advancements in neurosurgical robotics have improved medical procedures, particularly deep brain stimulation, where robots combine human and machine intelligence to precisely implant electrodes in the brain. While effective, this procedure…
Sound can exert forces on objects of any material and shape. This has made the contactless manipulation of objects by intense ultrasound a fascinating area of research with wide-ranging applications. While much is understood for acoustic…
We here present work a generalized low-level technical framework aimed to provide musical biofeedback in post-stroke balance and gait rehabilitation, built by an iterative user-centered process. The framework comprises wireless wearable…
Cross-frequency interactions are fundamental brain mechanisms for integrating information across temporal scales. However, accurate identification of these couplings is hindered by complex multi-frequency nonlinearities and by spurious,…
In order to gain a mechanistic understanding of how tinnitus emerges in the brain, we must build biologically plausible computational models that mimic both tinnitus development and perception, and test the tentative models with brain and…
Subband-based approaches process subbands in parallel through the model with shared parameters to learn the commonality of local spectrums for noise reduction. In this way, they have achieved remarkable results with fewer parameters.…
Deciding on an appropriate intervention requires a causal model of a treatment, the outcome, and potential mediators. Causal mediation analysis lets us distinguish between direct and indirect effects of the intervention, but has mostly been…
The computational underpinnings of positive psychotic symptoms have recently received significant attention. Candidate mechanisms include some combination of maladaptive priors and reduced updating of these priors during perception. A…
Transcranial low-intensity focused ultrasound can deliver energy to the brain in a minimally invasive manner for neuromodulation applications. However, continuous sonication through the skull introduces significant wave interactions,…
Consonance is related to the perception of pleasantness arising from a combination of sounds and has been approached quantitatively using mathematical relations, physics, information theory, and psychoacoustics. Tonal consonance is present…
Despite many years of research, the quest to identify neural correlates of perceptual consciousness (NCC) remains unresolved. One major obstacle lies in methodological limitations: most studies rely on non-invasive neural measures with…
In this paper we study how to shape temporal pulses to switch a bistable system between its stable steady states. Our motivation for pulse-based control comes from applications in synthetic biology, where it is generally difficult to…
In recent years, non-invasive neuro-modulation methods such as Focused Ultrasound (FUS) have gained popularity. The aim of this work is to introduce the use of existing open-source technology for surgical navigation to the field of…
Response variability limits the clinical utility of transcutaneous auricular vagus nerve stimulation (taVNS) for negative symptoms in treatment-resistant schizophrenia (TRS). This study aimed to develop an electroencephalography (EEG)-based…