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Diffusion models face significant challenges when employed for large-scale medical image reconstruction in real practice such as 3D Computed Tomography (CT). Due to the demanding memory, time, and data requirements, it is difficult to train…
Snapshot compressive spectral imaging reconstruction aims to reconstruct three-dimensional spatial-spectral images from a single-shot two-dimensional compressed measurement. Existing state-of-the-art methods are mostly based on deep…
Diffusion Posterior Sampling(DPS) methodology is a novel framework that permits nonlinear CT reconstruction by integrating a diffusion prior and an analytic physical system model, allowing for one-time training for different applications.…
Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…
Diffusion models, as powerful generative models, have found a wide range of applications and shown great potential in solving image reconstruction problems. Some works attempted to solve MRI reconstruction with diffusion models, but these…
Deep learning-based automated diagnosis of lung cancer has emerged as a crucial advancement that enables healthcare professionals to detect and initiate treatment earlier. However, these models require extensive training datasets with…
Cone-beam computed tomography (CBCT) is widely used in image-guided radiotherapy. Reconstructing CBCTs from limited-angle acquisitions (LA-CBCT) is highly desired for improved imaging efficiency, dose reduction, and better mechanical…
Deep image prior (DIP) has been successfully applied to positron emission tomography (PET) image restoration, enabling represent implicit prior using only convolutional neural network architecture without training dataset, whereas the…
Low-dose Computed Tomography (LDCT) reconstruction is an important task in medical image analysis. Recent years have seen many deep learning based methods, proved to be effective in this area. However, these methods mostly follow a…
Image-generative artificial intelligence (AI) has garnered significant attention in recent years. In particular, the diffusion model, a core component of generative AI, produces high-quality images with rich diversity. In this study, we…
Spectral computed tomography (CT) with photon-counting detectors holds immense potential for material discrimination and tissue characterization. However, under ultra-low-dose conditions, the sharply degraded signal-to-noise ratio (SNR) in…
To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…
We present a tomographic imaging technique, termed Deep Prior Diffraction Tomography (DP-DT), to reconstruct the 3D refractive index (RI) of thick biological samples at high resolution from a sequence of low-resolution images collected…
In this work, we introduce a new deep learning approach based on diffusion posterior sampling (DPS) to perform material decomposition from spectral CT measurements. This approach combines sophisticated prior knowledge from unsupervised…
The reconstruction of X-rays CT images from sparse or limited-angle geometries is a highly challenging task. The lack of data typically results in artifacts in the reconstructed image and may even lead to object distortions. For this…
Accurate attenuation and scatter corrections are crucial in positron emission tomography (PET) imaging for accurate visual interpretation and quantitative analysis. Traditional methods relying on computed tomography (CT) or magnetic…
We introduce Diffusion Active Learning, a novel approach that combines generative diffusion modeling with data-driven sequential experimental design to adaptively acquire data for inverse problems. Although broadly applicable, we focus on…
Positron emission tomography (PET) with 18F-Fluorodeoxyglucose (FDG) is an established tool in the diagnostic workup of patients with suspected dementing disorders. However, compared to the routinely available magnetic resonance imaging…
Photon-counting computed tomography (PCCT) has emerged as a promising imaging technique, enabling spectral imaging and material decomposition (MD). However, images typically suffer from a low signal-to-noise ratio (SNR) due to constraints…
Magnetic Resonance (MR) imaging plays an essential role in contemporary clinical diagnostics. It is increasingly integrated into advanced therapeutic workflows, such as hybrid Positron Emission Tomography/Magnetic Resonance (PET/MR) imaging…