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Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

Neurons and Cognition · Quantitative Biology 2022-08-15 Ganchao Wei , Ian H. Stevenson

Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…

Neurons and Cognition · Quantitative Biology 2017-12-18 Clemens Korndörfer , Ekkehard Ullner , Jordi García-Ojalvo , Gordon Pipa

Cardiac and respiratory rhythms are known to exhibit a modest degree of phase synchronization, which is affected by age, diseases, and other factors. We study the fine temporal structure of this synchrony in healthy young, healthy elderly,…

Tissues and Organs · Quantitative Biology 2021-04-26 Sungwoo Ahn , Jessica Solfest1 , Leonid L Rubchinsky

We report on the origin of synchronized bursting dynamics in various networks of neural spiking oscillators, when a certain threshold in coupling strength is exceeded. These ensembles synchronize at relatively low coupling strength and lose…

Chaotic Dynamics · Physics 2007-05-23 Mikhail V. Ivanchenko , Grigory V. Osipov , Vladimir D. Shalfeev , Jurgen Kurths

Neurons integrate synaptic inputs and convert them to action potential output at electrically distant locations. The computational power of a neuron is hence enhanced by subcellular compartmentalization and nonlinear synaptic integration,…

Neurons and Cognition · Quantitative Biology 2024-08-13 Jaeyoung Yoon

It is well known that synchronization patterns and coherence have a major role in the functioning of brain networks, both in pathological and in healthy states. In particular, in the perception of sound, one can observe an increase in…

Adaptation and Self-Organizing Systems · Physics 2024-02-01 Jakub Sawicki , Eckehard Schöll

Spontaneous fluctuations of the BOLD (Blood Oxygen Level-Dependent) signal, measured with fMRI (functional Magnetic Resonance Imaging), display a rich and neurobiologically relevant functional connectivity structure. This structure is…

Neurons and Cognition · Quantitative Biology 2012-09-24 Enzo Tagliazucchi , Frederic von Wegner , Astrid Morzelewski , Verena Brodbeck , Helmut Laufs

Background: The roles of neuromodulation in a neural network, such as in a cortical microcolumn, are still incompletely understood. Neuromodulation influences neural processing by presynaptic and postsynaptic regulation of synaptic…

Neurons and Cognition · Quantitative Biology 2019-06-25 Gabriele Scheler

Our current understanding of brain rhythms is based on quantifying their instantaneous or time-averaged characteristics. What remains unexplored, is the actual structure of the waves -- their shapes and patterns over finite timescales. To…

Neurons and Cognition · Quantitative Biology 2022-05-10 Clarissa Hoffman , Jingheng Cheng , Daoyun Ji , Y. Dabaghian

This perspective article investigates how auditory stimuli influence neural network dynamics using the FitzHugh-Nagumo (FHN) model and empirical brain connectivity data. Results show that synchronization is sensitive to both the frequency…

Neurons and Cognition · Quantitative Biology 2025-04-11 Jakub Sawicki

Glioma cells can reshape functional neuronal networks by hijacking neuronal synapses, leading to partial or complete neurological dysfunction. These mechanisms have been previously explored for language functions. However, the impact of…

In neural systems, synaptic plasticity is usually driven by spike trains. Due to the inherent noises of neurons, synapses and networks, spike trains typically exhibit externally uncontrollable variability such as spatial heterogeneity and…

Neurons and Cognition · Quantitative Biology 2015-06-18 Zedong Bi , Changsong Zhou , Hai-Jun Zhou

We study the dynamical behaviors of this improved memristive neuron model by changing external harmonic current and the magnetic gain parameters. The model shows rich dynamics including periodic and chaotic spiking and bursting, and…

Adaptation and Self-Organizing Systems · Physics 2020-03-03 Marius E. Yamakou

Neural activity exhibits a vast range of timescales that can be several fold larger than the membrane time constant of individual neurons. Two types of mechanisms have been proposed to explain this conundrum. One possibility is that large…

Neurons and Cognition · Quantitative Biology 2019-03-26 Manuel Beiran , Srdjan Ostojic

Many of the amazing functional capabilities of the brain are collective properties stemming from the interactions of large sets of individual neurons. In particular, the most salient collective phenomena in brain activity are oscillations,…

Neurons and Cognition · Quantitative Biology 2022-06-29 Victor Buendía , Pablo Villegas , Raffaella Burioni , Miguel A. Muñoz

Heterogeneity of firing rate statistics is known to have severe consequences on neural coding. Recent experimental recordings in weakly electric fish indicate that the distribution-width of superficial pyramidal cell firing rates (trial-…

Neurons and Cognition · Quantitative Biology 2017-08-14 Cheng Ly , Gary Marsat

Increasing experimental evidence suggests that axonal action potential conduction velocity is a highly adaptive parameter in the adult central nervous system. Yet, the effects of this newfound plasticity on global brain dynamics is poorly…

Neurons and Cognition · Quantitative Biology 2019-03-26 Vladimir A. Ivanov , Ioannis E. Polykretis , Konstantinos P. Michmizos

A new type of intermittent behavior is described to occur near the boundary of phase synchronization regime of coupled chaotic oscillators. This mechanism, called ring intermittency, arises for sufficiently high initial mismatches in the…

Chaotic Dynamics · Physics 2007-05-23 Alexander E. Hramov , Alexey A. Koronovskii , Maria K. Kurovskaya , S. Boccaletti

In the brain, coherent neuronal activities often appear simultaneously in multiple frequency bands, e.g., as combinations of alpha (8-12 Hz), beta (12.5-30 Hz), gamma (30-120 Hz) oscillations, among others. These rhythms are believed to…

Neurons and Cognition · Quantitative Biology 2023-04-26 Tianyi Wu , Yuhang Cai , Ruilin Zhang , Zhongyi Wang , Louis Tao , Zhuo-Cheng Xiao

Brain rhythms contribute to every aspect of brain function. Here, we study critical and resonance phenomena that precede the emergence of brain rhythms. Using an analytical approach and simulations of a cortical circuit model of neural…

Disordered Systems and Neural Networks · Physics 2015-06-12 A. V. Goltsev , M. A. Lopes , K. -E. Lee , J. F. F. Mendes