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Motion estimation of organs in a sequence of images is important in numerous medical imaging applications. The focus of this paper is the analysis of 4D Respiratory Correlated Computed Tomography (RCCT) Imaging. It is hypothesized that the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Markus D. Foote , Pouya Sabouri , Amit Sawant , Sarang C. Joshi

3D Cone-Beam CT (CBCT) is widely used in radiotherapy but suffers from motion artifacts due to breathing. A common clinical approach mitigates this by sorting projections into respiratory phases and reconstructing images per phase, but this…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Yuliang Huang , Imraj Singh , Thomas Joyce , Kris Thielemans , Jamie R. McClelland

Four-dimensional MRI (4D-MRI) is an promising technique for capturing respiratory-induced motion in radiation therapy planning and delivery. Conventional 4D reconstruction methods, which typically rely on phase binning or separate template…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Xinyang Wu , Muheng Li , Xia Li , Orso Pusterla , Sairos Safai , Philippe C. Cattin , Antony J. Lomax , Ye Zhang

Objective: Four-dimensional computed tomography (4DCT) imaging consists in reconstructing a CT acquisition into multiple phases to track internal organ and tumor motion. It is commonly used in radiotherapy treatment planning to establish…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yi-Heng Cao , Vincent Bourbonne , François Lucia , Ulrike Schick , Julien Bert , Vincent Jaouen , Dimitris Visvikis

Four-dimensional cone-beam computed tomography (4D CBCT) provides respiration-resolved images and can be used for image-guided radiation therapy. However, the ability to reveal respiratory motion comes at the cost of image artifacts. As raw…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Ziheng Deng , Hua Chen , Yongzheng Zhou , Haibo Hu , Zhiyong Xu , Jiayuan Sun , Tianling Lyu , Yan Xi , Yang Chen , Jun Zhao

Four-dimensional computed tomography (4DCT) is essential for medical imaging applications like radiotherapy, which demand precise respiratory motion representation. Traditional methods for reconstructing 4DCT data suffer from artifacts and…

Medical Physics · Physics 2025-07-21 Antoine De Paepe , Alexandre Bousse , Clémentine Phung-Ngoc , Dimitris Visvikis

Modeling of respiratory motion is important for a more accurate understanding and accounting of its effect on dose to cancers in the thorax and abdomen by radiotherapy. We have developed a model of respiration-induced organ motion in the…

Purpose: Functional imaging is emerging as an important tool for lung cancer treatment planning and evaluation. Compared with traditional methods such as nuclear medicine ventilation-perfusion (VQ), positron emission tomography (PET),…

The rapidly increasing prevalence of debilitating breathing disorders, such as chronic obstructive pulmonary disease (COPD), calls for a meaningful integration of artificial intelligence (AI) into healthcare. While this promises improved…

Medical Physics · Physics 2022-10-07 Harry J. Davies , Ghena Hammour , Hongjian Xiao , Danilo P. Mandic

Non-contact laser ablation, a precise thermal technique, simultaneously cuts and coagulates tissue without the insertion errors associated with rigid needles. Human organ motions, such as those in the liver, exhibit rhythmic components…

Robotics · Computer Science 2025-01-22 Yongjun Yan , Qingpeng Ding , Mingwu Li , Junyan Yan , Shing Shin Cheng

In this work, we develop a neural network-based method to convert a noisy motion signal generated from segmenting rebinned list-mode cardiac SPECT images, to that of a high-quality surrogate signal, such as those seen from external motion…

Image and Video Processing · Electrical Eng. & Systems 2022-08-03 Akshay Iyer , Clifford Lindsay , Hendrik Pretorius , Michael King

A precise spatial delivery of the radiation dose is crucial for the treatment success in radiotherapy. In the lung and upper abdominal region, respiratory motion introduces significant treatment uncertainties, requiring special motion…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jan Boysen , Hristina Uzunova , Heinz Handels , Jan Ehrhardt

This paper develops a surrogate model refinement approach for the simulation of dynamical systems and the solution of optimization problems governed by dynamical systems in which surrogates replace expensive-to-compute state- and…

Optimization and Control · Mathematics 2025-09-08 Jonathan R. Cangelosi , Matthias Heinkenschloss

Mathematical models of the human heart are increasingly playing a vital role in understanding the working mechanisms of the heart, both under healthy functioning and during disease. The aim is to aid medical practitioners diagnose and treat…

Numerical Analysis · Mathematics 2023-11-13 Sridhar Chellappa , Barış Cansız , Lihong Feng , Peter Benner , Michael Kaliske

Parametric reduced-order modelling often serves as a surrogate method for hemodynamics simulations to improve the computational efficiency in many-query scenarios or to perform real-time simulations. However, the snapshots of the method…

Computational Engineering, Finance, and Science · Computer Science 2023-10-24 Dongwei Ye , Valeria Krzhizhanovskaya , Alfons G. Hoekstra

Reconstructing dynamic, time-varying scenes with computed tomography (4D-CT) is a challenging and ill-posed problem common to industrial and medical settings. Existing 4D-CT reconstructions are designed for sparse sampling schemes that…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Albert W. Reed , Hyojin Kim , Rushil Anirudh , K. Aditya Mohan , Kyle Champley , Jingu Kang , Suren Jayasuriya

High-fidelity numerical simulations of chaotic, high dimensional nonlinear dynamical systems are computationally expensive, necessitating the development of efficient surrogate models. Most surrogate models for such systems are…

Machine Learning · Computer Science 2026-03-16 Dibyajyoti Chakraborty , Hojin Kim , Romit Maulik

We present a hybrid sampling-surrogate approach for reducing the computational expense of uncertainty quantification in nonlinear dynamical systems. Our motivation is to enable rapid uncertainty quantification in complex mechanical systems…

Computation · Statistics 2022-01-27 Hang Yang , Yuji Fujii , K. W. Wang , Alex A. Gorodetsky

Data-driven respiratory signal extraction from rotational X-ray scans is a challenge as angular effects overlap with respiration-induced change in the scene. In this paper, we use the linearity of the X-ray transform to propose a bilinear…

Computer Vision and Pattern Recognition · Computer Science 2018-11-06 Tobias Geimer , Paul Keall , Katharina Breininger , Vincent Caillet , Michelle Dunbar , Christoph Bert , Andreas Maier

Predictive estimation, which comprises model calibration, model prediction, and validation, is a common objective when performing inverse uncertainty quantification (UQ) in diverse scientific applications. These techniques typically require…

Numerical Analysis · Mathematics 2024-07-17 Ningxin Yang , Truong Le , Lidija Zdravković , David M. Potts
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