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Large language models (LLMs) are currently being used to answer medical questions across a variety of clinical domains. Recent top-performing commercial LLMs, in particular, are also capable of citing sources to support their responses. In…

Computation and Language · Computer Science 2024-02-06 Kevin Wu , Eric Wu , Ally Cassasola , Angela Zhang , Kevin Wei , Teresa Nguyen , Sith Riantawan , Patricia Shi Riantawan , Daniel E. Ho , James Zou

Retrieval-Augmented Generation (RAG) offers a promising solution to address various limitations of Large Language Models (LLMs), such as hallucination and difficulties in keeping up with real-time updates. This approach is particularly…

Computation and Language · Computer Science 2024-06-18 Shuting Wang , Jiongnan Liu , Shiren Song , Jiehan Cheng , Yuqi Fu , Peidong Guo , Kun Fang , Yutao Zhu , Zhicheng Dou

Background: Over the past few decades, the process and methodology of automated question generation (AQG) have undergone significant transformations. Recent progress in generative natural language models has opened up new potential in the…

Artificial Intelligence · Computer Science 2024-12-06 Dominic Lohr , Marc Berges , Abhishek Chugh , Michael Kohlhase , Dennis Müller

The use of Large Language Models (LLMs) to support tasks in software development has steadily increased over recent years. From assisting developers in coding activities to providing conversational agents that answer newcomers' questions.…

Objective: To demonstrate the capabilities of Large Language Models (LLMs) as autonomous agents to reproduce findings of published research studies using the same or similar dataset. Materials and Methods: We used the "Quick Access" dataset…

Computation and Language · Computer Science 2025-06-02 Nic Dobbins , Christelle Xiong , Kristine Lan , Meliha Yetisgen

Large language models (LLMs) have been shown to be proficient in correctly answering questions in the context of online discourse. However, the study of using LLMs to model human-like answers to fact-driven social media questions is still…

Computation and Language · Computer Science 2024-04-02 Parker Seegmiller , Joseph Gatto , Omar Sharif , Madhusudan Basak , Sarah Masud Preum

Retrieval-augmented generation (RAG) has emerged as an approach to augment large language models (LLMs) by reducing their reliance on static knowledge and improving answer factuality. RAG retrieves relevant context snippets and generates an…

Computation and Language · Computer Science 2025-02-21 Juraj Vladika , Florian Matthes

Purpose: Large Language Models (LLMs) hold significant promise for medical applications. Retrieval Augmented Generation (RAG) emerges as a promising approach for customizing domain knowledge in LLMs. This case study presents the development…

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

The retrieval-augmented generation (RAG) approach is used to reduce the confabulation of large language models (LLMs) for question answering by retrieving and providing additional context coming from external knowledge sources (e.g., by…

Computation and Language · Computer Science 2024-10-30 Alexander Bondarenko , Adrian Viehweger

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Large Language Models (LLMs) are tools that have become indispensable in development and programming. However, they suffer from hallucinations, especially when dealing with unknown knowledge. This is particularly the case when LLMs are to…

Computation and Language · Computer Science 2026-05-05 Andreas Baumann , Peter Eberhard

Large Language Models (LLMs) have demonstrated promise in medical knowledge assessments, yet their practical utility in real-world clinical decision-making remains underexplored. In this study, we evaluated the performance of three…

Computation and Language · Computer Science 2025-12-30 Mengdi Chai , Ali R. Zomorrodi

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Although large language models (LLMs) often produce impressive outputs, it remains unclear how they perform in real-world scenarios requiring strong reasoning skills and expert domain knowledge. We set out to investigate whether close- and…

Computation and Language · Computer Science 2023-12-27 Valentin Liévin , Christoffer Egeberg Hother , Andreas Geert Motzfeldt , Ole Winther

In recent years, Large Language Models (LLMs) have gained immense attention due to their notable emergent capabilities, surpassing those seen in earlier language models. A particularly intriguing application of LLMs is their role as…

Computation and Language · Computer Science 2023-11-02 Xue-Yong Fu , Md Tahmid Rahman Laskar , Cheng Chen , Shashi Bhushan TN

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

Computation and Language · Computer Science 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

Automatic evaluation is an integral aspect of dialogue system research. The traditional reference-based NLG metrics are generally found to be unsuitable for dialogue assessment. Consequently, recent studies have suggested various unique,…

Computation and Language · Computer Science 2024-01-23 Chen Zhang , Luis Fernando D'Haro , Yiming Chen , Malu Zhang , Haizhou Li

Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the…

Human-Computer Interaction · Computer Science 2026-04-23 Gaoussou Youssouf Kebe , Jeffrey M. Girard , Einat Liebenthal , Justin Baker , Fernando De la Torre , Louis-Philippe Morency